ras-related C3 botulinum toxin substrate 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:227.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:258.10 spine:- retina:- eye:142.20 artery/aorta:714.30 vein:- lymphnode:- peripheral blood:- spleen:390 thymus:- bone marrow:- adipose:294.40 bone:156.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1139 placenta:477.90 prostate:379.60 ovary:228.20 testis:- heart:329.60 muscle:- esophagus:- stomach:- intestine:314 colon:-     liver/hepato:252.60        lung:506.60    bladder:- kidney:319 pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:227.60 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_134366
Gene ID 363875
Unigene ID Rn.29157
Probe set ID -
Ensembl ID ENSRNOG00000001068

Orthologous Gene

Human[3]  NM_006908, NM_018890
Mouse[2]  NM_009007, NM_018890

Chromosomal Region

12p11  [11,380,314  -  11,400,531]

Gene Family (Interpro ID)

IPR013684  MIRO-like
IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR003577  Ras small GTPase, Ras type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

8631991
8910292
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Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0007015  actin filament organization
GO:0048532  anatomical structure arrangement
GO:0002093  auditory receptor cell morphogenesis
GO:0007411  axon guidance
GO:0045453  bone resorption
GO:0007155  cell adhesion
GO:0016477  cell migration
GO:0048870  cell motility
GO:0008283  cell proliferation
GO:0045216  cell-cell junction organization
GO:0006928  cellular component movement
GO:0021799  cerebral cortex radially oriented cell migration
GO:0006935  chemotaxis
GO:0090103  cochlea morphogenesis
GO:0007010  cytoskeleton organization
GO:0016358  dendrite development
GO:0048813  dendrite morphogenesis
GO:0021831  embryonic olfactory bulb interneuron precursor migration
GO:0006897  endocytosis
GO:0043652  engulfment of apoptotic cell
GO:0003382  epithelial cell morphogenesis
GO:0006184  GTP catabolic process
GO:0006972  hyperosmotic response
GO:0030032  lamellipodium assembly
GO:0051668  localization within membrane
GO:0002551  mast cell chemotaxis
GO:0032707  negative regulation of interleukin-23 production
GO:0006911  phagocytosis, engulfment
GO:0030838  positive regulation of actin filament polymerization
GO:0045740  positive regulation of DNA replication
GO:0010592  positive regulation of lamellipodium assembly
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0016601  Rac protein signal transduction
GO:0030334  regulation of cell migration
GO:0060263  regulation of respiratory burst
GO:0031529  ruffle organization
GO:0007264  small GTPase mediated signal transduction
GO:0034446  substrate adhesion-dependent cell spreading
GO:0060071  Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0031410  cytoplasmic vesicle
GO:0019897  extrinsic to plasma membrane
GO:0000139  Golgi membrane
GO:0030027  lamellipodium
GO:0042470  melanosome
GO:0016020  membrane
GO:0001891  phagocytic cup
GO:0032587  ruffle membrane
GO:0005802  trans-Golgi network

Molecular Function

GO:0019899  enzyme binding
GO:0005525  GTP binding
GO:0030742  GTP-dependent protein binding
GO:0003924  GTPase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0017137  Rab GTPase binding
GO:0031996  thioesterase binding