Eph receptor A2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:177.70 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:82.30 heart:58.20 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108977
Gene ID 366492
Unigene ID Rn.23415
Probe set ID -
Ensembl ID ENSRNOG00000009222

Orthologous Gene

Human[1]  NM_004431
Mouse[1]  NM_010139

Chromosomal Region

5q36  [160,185,253  -  160,214,727]

Gene Family (Interpro ID)

IPR001090  Ephrin receptor, ligand binding
IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR021129  Sterile alpha motif, type 1
IPR011510  Sterile alpha motif, type 2
IPR013761  Sterile alpha motif-type
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016257  Tyrosine-protein kinase, ephrin receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

11711206
14871820
15561974
15671251
16359662
16735461
18387945
19684201

Gene Ontology  (GO ID)

Biological Process

GO:0032863  activation of Rac GTPase activity
GO:0048320  axial mesoderm formation
GO:0001568  blood vessel development
GO:0046849  bone remodeling
GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0060326  cell chemotaxis
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0048013  ephrin receptor signaling pathway
GO:0030216  keratinocyte differentiation
GO:0070309  lens fiber cell morphogenesis
GO:0033598  mammary gland epithelial cell proliferation
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0021915  neural tube development
GO:0030182  neuron differentiation
GO:0060035  notochord cell development
GO:0014028  notochord formation
GO:0048570  notochord morphogenesis
GO:0001649  osteoblast differentiation
GO:0030316  osteoclast differentiation
GO:0090004  positive regulation of establishment of protein localization in plasma membrane
GO:0043491  protein kinase B signaling cascade
GO:0045765  regulation of angiogenesis
GO:0043535  regulation of blood vessel endothelial cell migration
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0010591  regulation of lamellipodium assembly
GO:0070848  response to growth factor stimulus
GO:0001501  skeletal system development
GO:0001570  vasculogenesis

Cellular Component

GO:0005925  focal adhesion
GO:0005887  integral to plasma membrane
GO:0031256  leading edge membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005003  ephrin receptor activity
GO:0004714  transmembrane receptor protein tyrosine kinase activity