gap junction protein, alpha 5

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.19 cerebellum:8.32 brain stem:8.62 corpus callosum/glia:- pineal gland:- peripheral nerve:8.25 spine:- retina:- eye:8.37 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.99 thymus:7.92 bone marrow:8.39 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:193.90 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:202.60    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:8.18 muscle:8.28 esophagus:- stomach:- intestine:7.90 colon:7.75 liver/hepato:- lung:- bladder:- kidney:8.05 pituitary:8 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_019280
Gene ID 50563
Unigene ID Rn.88300
Probe set ID M76535cds_at  [RG_U34A]
Ensembl ID ENSRNOG00000017484

Orthologous Gene

Human[2]  NM_005266, NM_181703
Mouse[2]  NM_008121, NM_181703

Chromosomal Region

2q34  [191,824,096  -  191,843,865]

Gene Family (Interpro ID)

IPR000500  Connexins
IPR002264  Gap junction alpha-5 protein (Cx40)

Link to Pubmed  (Pubmed ID)

1310450
1328644
1370487
7554128
8944820
9403066
9709407
9851942
10990491
11306811
11422751
11527649
11557558
11821709
11889564
12477932
12644912
14693688
15016632
15381756
15489334
15678088
15942348
16037574
16284078
16352648
16790700
16815985
17546509
17584645
17632690
17855776
17928514
18046320
18324386
19077877
19129462
19465552
19588758
19686729
20609064
20805582
21414209
21543330
21895483
22199024
22336507
22403875
22945766

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0048844  artery morphogenesis
GO:0003283  atrial septum development
GO:0060413  atrial septum morphogenesis
GO:0003294  atrial ventricular junction remodeling
GO:0001568  blood vessel development
GO:0003161  cardiac conduction system development
GO:0010643  cell communication by chemical coupling
GO:0010644  cell communication by electrical coupling
GO:0035050  embryonic heart tube development
GO:0030326  embryonic limb morphogenesis
GO:0003158  endothelium development
GO:0016264  gap junction assembly
GO:0007507  heart development
GO:0003174  mitral valve development
GO:0045776  negative regulation of blood pressure
GO:0003105  negative regulation of glomerular filtration
GO:0003151  outflow tract morphogenesis
GO:0010652  positive regulation of cell communication by chemical coupling
GO:0045907  positive regulation of vasoconstriction
GO:0045909  positive regulation of vasodilation
GO:0006813  potassium ion transport
GO:0051259  protein oligomerization
GO:0003193  pulmonary valve formation
GO:0060371  regulation of atrial cardiomyocyte membrane depolarization
GO:0055117  regulation of cardiac muscle contraction
GO:0003073  regulation of systemic arterial blood pressure
GO:0042312  regulation of vasodilation
GO:0060373  regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307  regulation of ventricular cardiomyocyte membrane repolarization
GO:0003071  renal system process involved in regulation of systemic arterial blood pressure
GO:0003284  septum primum development
GO:0001501  skeletal system development
GO:0003281  ventricular septum development
GO:0060412  ventricular septum morphogenesis

Cellular Component

GO:0042995  cell projection
GO:0005922  connexon complex
GO:0005921  gap junction
GO:0005887  integral to plasma membrane
GO:0014704  intercalated disc

Molecular Function

GO:0071253  connexin binding
GO:0005243  gap junction channel activity
GO:0055077  gap junction hemi-channel activity