nuclear receptor co-repressor 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:248.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:312 thymus:245.80 bone marrow:- adipose:441.60 bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:75.90 ovary:- testis:- heart:135.70 muscle:- esophagus:- stomach:- intestine:732.70 colon:-     liver/hepato:13.30        lung:253.30    bladder:- kidney:- pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:170.70 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_577103
Gene ID 54299
Unigene ID Rn.24948
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

10q23  [48,481,481  -  48,628,543]

Gene Family (Interpro ID)

IPR009057  Homeodomain-like
IPR012287  Homeodomain-related
IPR014778  Myb, DNA-binding
IPR001005  SANT, DNA-binding

Link to Pubmed  (Pubmed ID)

9139820
9839950
10441327
10491148
10803578
11850121
12410313
12477932
15219413
15234273
15701601
15862975
15870285
15946693
16030140
16212947
16394250
16822624
17018285
17079677
17163421
18063853
19460436
19471584
19608741
19696011
20051490
20352046
20427468
20801081
20949361
21695276
21784126
22349439
23083128

Gene Ontology  (GO ID)

Biological Process

GO:0002361  CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0021549  cerebellum development
GO:0042632  cholesterol homeostasis
GO:0016568  chromatin modification
GO:0032922  circadian regulation of gene expression
GO:0060318  definitive erythrocyte differentiation
GO:0007595  lactation
GO:0010629  negative regulation of gene expression
GO:0046329  negative regulation of JNK cascade
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0008284  positive regulation of cell proliferation
GO:0031065  positive regulation of histone deacetylation
GO:0050790  regulation of catalytic activity
GO:0040014  regulation of multicellular organism growth
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0007519  skeletal muscle tissue development
GO:0051225  spindle assembly
GO:0021794  thalamus development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000118  histone deacetylase complex
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0016580  Sin3 complex
GO:0005876  spindle microtubule
GO:0005667  transcription factor complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0030331  estrogen receptor binding
GO:0042826  histone deacetylase binding
GO:0035033  histone deacetylase regulator activity
GO:0042975  peroxisome proliferator activated receptor binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0042974  retinoic acid receptor binding
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0046966  thyroid hormone receptor binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity