BCL2-like 11 (apoptosis facilitator)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.12 cerebellum:5.15 brain stem:5.60 corpus callosum/glia:- pineal gland:- peripheral nerve:5.43 spine:- retina:- eye:5.19 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:4.65 thymus:5.05 bone marrow:5.20 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:4.74 muscle:4.86 esophagus:- stomach:- intestine:4.79 colon:4.55 liver/hepato:- lung:- bladder:- kidney:4.84 pituitary:4.77 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_171989
Gene ID 64547
Unigene ID -
Probe set ID AF065432_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000016551

Orthologous Gene

Human[5]  NM_001204106, NM_001204107, NM_001204108, NM_001204109, NM_001204110, NM_001204111, NM_001204112, NM_001204113, NM_006538, NM_138621, NM_138622, NM_138623, NM_138624, NM_138625, NM_138626, NM_138627, NM_207002, NM_207003
Mouse[30]  NM_009754, NM_207680, NM_207681, NM_001204109, NM_001204110, NM_001204111, NM_001204112, NM_001204113, NM_006538, NM_138621, NM_138622, NM_138623, NM_138624, NM_138625, NM_138626, NM_138627, NM_207002, NM_207003

Chromosomal Region

3q36  [115,689,686  -  115,722,701]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9731710
10576740
10579309
11495903
11968853
12388545
12818176
14667574
15356200
15384421
16092929
16092944
16162916
16282323
16431916
16818494
17251057
17287517
17658509
17702754
18058945
18195012
18351462
18465250
19438724
19641503
20857401
21164521
21378313
21439021
21451041
21478148
21762482
23661003
23815625
23828564
23896225
24567336

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006915  apoptosis
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0007420  brain development
GO:0007160  cell-matrix adhesion
GO:0060154  cellular process regulating host cell cycle in response to virus
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0043583  ear development
GO:0001701  in utero embryonic development
GO:0006917  induction of apoptosis
GO:0001822  kidney development
GO:0001776  leukocyte homeostasis
GO:0002260  lymphocyte homeostasis
GO:0008584  male gonad development
GO:0030879  mammary gland development
GO:0002262  myeloid cell homeostasis
GO:0042475  odontogenesis of dentine-containing tooth
GO:0048066  pigmentation during development
GO:0043065  positive regulation of apoptosis
GO:0060139  positive regulation of apoptosis by virus
GO:0043280  positive regulation of caspase activity
GO:0045787  positive regulation of cell cycle
GO:0043525  positive regulation of neuron apoptosis
GO:0032464  positive regulation of protein homooligomerization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0009791  post-embryonic development
GO:0048563  post-embryonic organ morphogenesis
GO:0042981  regulation of apoptosis
GO:0046620  regulation of organ growth
GO:0048070  regulation of pigmentation during development
GO:0034976  response to endoplasmic reticulum stress
GO:0007283  spermatogenesis
GO:0048536  spleen development
GO:0043029  T cell homeostasis
GO:0070242  thymocyte apoptosis
GO:0048538  thymus development
GO:0035148  tube lumen formation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0019898  extrinsic to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005874  microtubule
GO:0005739  mitochondrion

Molecular Function

GO:0008017  microtubule binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity