inositol polyphosphate phosphatase-like 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:151.80 ovary:228.20 testis:82.30 heart:96.90 muscle:797.20 esophagus:- stomach:- intestine:314 colon:-     liver/hepato:13.30        lung:50.70    bladder:- kidney:127.60 pituitary:177.70 thyroid/parathyroid:- adrenal gland:6535.90 pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_022944
Gene ID 65038
Unigene ID Rn.42902
Probe set ID -
Ensembl ID ENSRNOG00000019730

Orthologous Gene

Human[1]  NM_001567
Mouse[2]  NM_001122739, NM_010567

Chromosomal Region

1q32  [159,278,130  -  159,291,910]

Gene Family (Interpro ID)

IPR005135  Endonuclease/exonuclease/phosphatase
IPR000300  Inositol polyphosphate related phosphatase
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR021129  Sterile alpha motif, type 1
IPR011510  Sterile alpha motif, type 2
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

8889548
10381377
10648902
11343120
11692174
12086927
12453826
12933696
15220217
15983195
16155101
17327370
17371235
17535963
17893321
22247557

Gene Ontology  (GO ID)

Biological Process

GO:0007015  actin filament organization
GO:0007420  brain development
GO:0007155  cell adhesion
GO:0044255  cellular lipid metabolic process
GO:0001958  endochondral ossification
GO:0006897  endocytosis
GO:0006006  glucose metabolic process
GO:0032957  inositol trisphosphate metabolic process
GO:0008285  negative regulation of cell proliferation
GO:0008156  negative regulation of DNA replication
GO:0010629  negative regulation of gene expression
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0043569  negative regulation of insulin-like growth factor receptor signaling pathway
GO:0043407  negative regulation of MAP kinase activity
GO:0010977  negative regulation of neuron projection development
GO:0010642  negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0006661  phosphatidylinositol biosynthetic process
GO:0046856  phosphoinositide dephosphorylation
GO:0009791  post-embryonic development
GO:0042493  response to drug
GO:0032868  response to insulin stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0030175  filopodium
GO:0005794  Golgi apparatus
GO:0030027  lamellipodium
GO:0005886  plasma membrane

Molecular Function

GO:0003779  actin binding
GO:0004445  inositol-polyphosphate 5-phosphatase activity
GO:0005547  phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005515  protein binding
GO:0042169  SH2 domain binding
GO:0017124  SH3 domain binding