colony stimulating factor 1 (macrophage)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:78.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_023981
Gene ID 78965
Unigene ID Rn.83632
Probe set ID -
Ensembl ID ENSRNOG00000018659

Orthologous Gene

Human[11]  NM_000757, NM_172210, NM_172211, NM_172212
Mouse[11]  NM_001113529, NM_001113530, NM_007778, NM_172212

Chromosomal Region

2q34  [203,292,765  -  203,307,965]

Gene Family (Interpro ID)

IPR009079  Four-helical cytokine-like, core

Link to Pubmed  (Pubmed ID)

8357831
8573750
9158105
9637704
11340249
11477167
11981428
12029068
12038073
12074592
12110011
12379742
12477932
14696961
15203935
15205327
15383612
15728459
16166801
16304045
16618760
16883060
16951369
17068143
17659436
18172291
18510570
18981160
19196448
19219684
19242505
19893052
20628067
20831658
21176538
21885670
22052465
22441309
22700848
22846308
23143303
23443487
23628901
23711477

Gene Ontology  (GO ID)

Biological Process

GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0008283  cell proliferation
GO:0048873  homeostasis of number of cells within a tissue
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030225  macrophage differentiation
GO:0060763  mammary duct terminal end bud growth
GO:0060611  mammary gland fat development
GO:0007275  multicellular organismal development
GO:0042476  odontogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010628  positive regulation of gene expression
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0045651  positive regulation of macrophage differentiation
GO:0045657  positive regulation of monocyte differentiation
GO:0032946  positive regulation of mononuclear cell proliferation
GO:0040018  positive regulation of multicellular organism growth
GO:0042488  positive regulation of odontogenesis of dentine-containing tooth
GO:0045672  positive regulation of osteoclast differentiation
GO:0045860  positive regulation of protein kinase activity
GO:0046579  positive regulation of Ras protein signal transduction
GO:0030278  regulation of ossification
GO:0003006  reproductive developmental process

Cellular Component

GO:0005615  extracellular space
GO:0005887  integral to plasma membrane
GO:0048471  perinuclear region of cytoplasm
GO:0043235  receptor complex

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0005157  macrophage colony stimulating factor receptor binding
GO:0042803  protein homodimerization activity