hematopoietically expressed homeobox

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:156 thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:39.90        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_024385
Gene ID 79237
Unigene ID Rn.12188
Probe set ID -
Ensembl ID ENSRNOG00000016595

Orthologous Gene

Human[2]  NM_002729
Mouse[1]  NM_008245

Chromosomal Region

1q53  [241,736,542  -  241,742,129]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

10085234
10871399
11139473
11291863
12477932
15016828

Gene Ontology  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0030183  B cell differentiation
GO:0007049  cell cycle
GO:0030154  cell differentiation
GO:0008283  cell proliferation
GO:0071103  DNA conformation change
GO:0035050  embryonic heart tube development
GO:0048568  embryonic organ development
GO:0007492  endoderm development
GO:0030900  forebrain development
GO:0048853  forebrain morphogenesis
GO:0030097  hemopoiesis
GO:0070365  hepatocyte differentiation
GO:0001701  in utero embryonic development
GO:0022027  interkinetic nuclear migration
GO:0001889  liver development
GO:0002009  morphogenesis of an epithelium
GO:0006406  mRNA export from nucleus
GO:0035264  multicellular organism growth
GO:0002573  myeloid leukocyte differentiation
GO:0016525  negative regulation of angiogenesis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030948  negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0009887  organ morphogenesis
GO:0031016  pancreas development
GO:0016973  poly(A)+ mRNA export from nucleus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0060431  primary lung bud formation
GO:0090009  primitive streak formation
GO:0034504  protein localization in nucleus
GO:0042127  regulation of cell proliferation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0043434  response to peptide hormone stimulus
GO:0009611  response to wounding
GO:0007165  signal transduction
GO:0030878  thyroid gland development
GO:0048729  tissue morphogenesis
GO:0001570  vasculogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0032993  protein-DNA complex

Molecular Function

GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0044212  DNA regulatory region binding
GO:0008190  eukaryotic initiation factor 4E binding
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding