v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:746.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.88 cerebellum:6.77 brain stem:6.77 corpus callosum/glia:- pineal gland:- peripheral nerve:6.80 spine:- retina:- eye:7.42 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:6.97 thymus:6.94 bone marrow:6.81 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6.58 muscle:6.67 esophagus:- stomach:- intestine:6.73 colon:6.54 liver/hepato:- lung:- bladder:- kidney:6.60 pituitary:6.87 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001111098
Gene ID 81515
Unigene ID Rn.43383
Probe set ID L14951_at  [RG_U34A]
Ensembl ID ENSRNOG00000008180

Orthologous Gene

Human[5]  NM_001111097, NM_002350
Mouse[4]  NM_001111096, NM_010747

Chromosomal Region

5q12  [16,933,106  -  17,054,560]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

1709169
8106508
8125304
8190127
8627181
8757630
8761480
8870703
8910399
9116282
9295361
9325302
9692543
10330413
10545487
10944523
11137137
11591756
11714805
11744621
11971018
12007793
12089343
12089355
12372808
12670955
12681493
12709437
14529711
14531861
14604964
14769131
15060019
15287886
15504915
15710354
16177098
16529858
16713446
16785509
16791881
17039281
17265464
17579026
17845203
17918263
17977829
18234883
18250449
18326662
18579528
18682390
19356729
19832701
22871113

Gene Ontology  (GO ID)

Biological Process

GO:0030262  apoptotic nuclear changes
GO:0001782  B cell homeostasis
GO:0050853  B cell receptor signaling pathway
GO:0031668  cellular response to extracellular stimulus
GO:0034605  cellular response to heat
GO:0071300  cellular response to retinoic acid
GO:0050663  cytokine secretion
GO:0030218  erythrocyte differentiation
GO:0002774  Fc receptor mediated inhibitory signaling pathway
GO:0002431  Fc receptor mediated stimulatory signaling pathway
GO:0030097  hemopoiesis
GO:0002553  histamine secretion by mast cell
GO:0002768  immune response-regulating cell surface receptor signaling pathway
GO:0045087  innate immune response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0030889  negative regulation of B cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0070667  negative regulation of mast cell proliferation
GO:0002762  negative regulation of myeloid leukocyte differentiation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0010741  negative regulation of protein kinase cascade
GO:0034136  negative regulation of toll-like receptor 2 signaling pathway
GO:0034144  negative regulation of toll-like receptor 4 signaling pathway
GO:0031175  neuron projection development
GO:0014003  oligodendrocyte development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0002576  platelet degranulation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0051272  positive regulation of cellular component movement
GO:0060369  positive regulation of Fc receptor mediated stimulatory signaling pathway
GO:0060252  positive regulation of glial cell proliferation
GO:0070668  positive regulation of mast cell proliferation
GO:0010976  positive regulation of neuron projection development
GO:0070447  positive regulation of oligodendrocyte progenitor proliferation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0042327  positive regulation of phosphorylation
GO:0070304  positive regulation of stress-activated protein kinase signaling pathway
GO:0042531  positive regulation of tyrosine phosphorylation of STAT protein
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0002902  regulation of B cell apoptosis
GO:0050855  regulation of B cell receptor signaling pathway
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0001817  regulation of cytokine production
GO:0050707  regulation of cytokine secretion
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0045646  regulation of erythrocyte differentiation
GO:0050727  regulation of inflammatory response
GO:0033003  regulation of mast cell activation
GO:0043304  regulation of mast cell degranulation
GO:0090025  regulation of monocyte chemotaxis
GO:0051279  regulation of release of sequestered calcium ion into cytosol
GO:0043200  response to amino acid stimulus
GO:0048678  response to axon injury
GO:0009743  response to carbohydrate stimulus
GO:0006974  response to DNA damage stimulus
GO:0042493  response to drug
GO:0009725  response to hormone stimulus
GO:0032868  response to insulin stimulus
GO:0014070  response to organic cyclic substance
GO:0043434  response to peptide hormone stimulus
GO:0006991  response to sterol depletion
GO:0009636  response to toxin
GO:0002513  tolerance induction to self antigen
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0034666  alpha2-beta1 integrin complex
GO:0005623  cell
GO:0005913  cell-cell adherens junction
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0045121  membrane raft
GO:0030061  mitochondrial crista
GO:0005758  mitochondrial intermembrane space
GO:0031966  mitochondrial membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0014069  postsynaptic density

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0043015  gamma-tubulin binding
GO:0043208  glycosphingolipid binding
GO:0005178  integrin binding
GO:0016301  kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0051219  phosphoprotein binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0005102  receptor binding
GO:0017124  SH3 domain binding
GO:0031625  ubiquitin protein ligase binding