transforming growth factor, beta receptor II

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Synonym

-

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.06 cerebellum:6.88 brain stem:7.36 corpus callosum/glia:- pineal gland:- peripheral nerve:7.12 spine:- retina:- eye:7.32 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.10 thymus:6.91 bone marrow:7.27 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.29 muscle:7.38 esophagus:- stomach:- intestine:7.02 colon:6.78 liver/hepato:- lung:- bladder:- kidney:7.14 pituitary:6.77 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

IDs

Refseq ID NM_031132
Gene ID 81810
Unigene ID -
Probe set ID L09653_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000013265

Orthologous Gene

Human[8]  NM_001024847, NM_003242
Mouse[4]  NM_009371, NM_029575

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0007568  aging
GO:0006915  apoptosis
GO:0007420  brain development
GO:0060433  bronchus development
GO:0060434  bronchus morphogenesis
GO:0051216  cartilage development
GO:0007182  common-partner SMAD protein phosphorylation
GO:0007566  embryo implantation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0009790  embryonic development
GO:0035162  embryonic hemopoiesis
GO:0007369  gastrulation
GO:0048565  gut development
GO:0007507  heart development
GO:0001701  in utero embryonic development
GO:0006917  induction of apoptosis
GO:0002088  lens development in camera-type eye
GO:0030324  lung development
GO:0060463  lung lobe morphogenesis
GO:0060425  lung morphogenesis
GO:0060443  mammary gland morphogenesis
GO:0043011  myeloid dendritic cell differentiation
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0009887  organ morphogenesis
GO:0031100  organ regeneration
GO:0060021  palate development
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0001569  patterning of blood vessels
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0002663  positive regulation of B cell tolerance induction
GO:0010634  positive regulation of epithelial cell migration
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0051138  positive regulation of NK T cell differentiation
GO:0043415  positive regulation of skeletal muscle tissue regeneration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0002666  positive regulation of T cell tolerance induction
GO:0002651  positive regulation of tolerance induction to self antigen
GO:0006468  protein amino acid phosphorylation
GO:0006898  receptor-mediated endocytosis
GO:0042127  regulation of cell proliferation
GO:0070723  response to cholesterol
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0009749  response to glucose stimulus
GO:0001666  response to hypoxia
GO:0009612  response to mechanical stimulus
GO:0007584  response to nutrient
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0048545  response to steroid hormone stimulus
GO:0007224  smoothened signaling pathway
GO:0060440  trachea formation
GO:0060439  trachea morphogenesis
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001570  vasculogenesis
GO:0042060  wound healing

Cellular Component

GO:0005901  caveola
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0045121  membrane raft
GO:0043235  receptor complex
GO:0070022  transforming growth factor beta receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0005539  glycosaminoglycan binding
GO:0046872  metal ion binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0050431  transforming growth factor beta binding
GO:0005024  transforming growth factor beta receptor activity
GO:0005026  transforming growth factor beta receptor activity, type II
GO:0004675  transmembrane receptor protein serine/threonine kinase activity
GO:0034713  type I transforming growth factor beta receptor binding
GO:0034714  type III transforming growth factor beta receptor binding