nuclear receptor coactivator 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:38.80 muscle:- esophagus:- stomach:- intestine:104.70 colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031822
Gene ID 83724
Unigene ID Rn.49136
Probe set ID -
Ensembl ID ENSRNOG00000007975

Orthologous Gene

Human[3]  NM_006540
Mouse[2]  NM_001077695, NM_008678

Chromosomal Region

5q11  [5,197,891  -  5,275,776]

Gene Family (Interpro ID)

IPR009110  Nuclear receptor coactivator, interlocking
IPR014920  Nuclear receptor coactivator, Ncoa-type, interlocking
IPR000014  PAS
IPR013767  PAS fold
IPR014935  Steroid receptor coactivator

Link to Pubmed  (Pubmed ID)

9742117
10803578
11007883
11306337
11734998
12089347
15234273
15539428
15912503
16189181
16394250
17084383
17163421
17481888
19471584
19818358
20166126
20660062
20678994
21784126
23132854
23759327

Gene Ontology  (GO ID)

Biological Process

GO:0021549  cerebellum development
GO:0008584  male gonad development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045925  positive regulation of female receptivity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0005794  Golgi apparatus
GO:0005874  microtubule
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0048786  presynaptic active zone
GO:0005791  rough endoplasmic reticulum

Molecular Function

GO:0003682  chromatin binding
GO:0070182  DNA polymerase binding
GO:0030331  estrogen receptor binding
GO:0035259  glucocorticoid receptor binding
GO:0004402  histone acetyltransferase activity
GO:0016922  ligand-dependent nuclear receptor binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257  nuclear hormone receptor binding
GO:0030165  PDZ domain binding
GO:0033142  progesterone receptor binding
GO:0032403  protein complex binding
GO:0046983  protein dimerization activity
GO:0005102  receptor binding
GO:0042974  retinoic acid receptor binding
GO:0046965  retinoid X receptor binding
GO:0004871  signal transducer activity
GO:0046966  thyroid hormone receptor binding
GO:0030375  thyroid hormone receptor coactivator activity
GO:0003713  transcription coactivator activity