adenosine deaminase

詳細情報を見る

同義遺伝子名

ADA, adenosine deaminase, Adenosine aminohydrolase, Adenosine deaminase

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.67 小脳:5.18 脳幹:5.52 脳梁:5.91 松果体:- 末梢神経:5.17 脊柱:5.36 網膜:- 目:- 動脈:6.81 静脈:6.41 リンパ節:6.77 末梢血:- 脾臓:6.63 胸腺:10.26 骨髄:6.40 脂肪:6.62 骨:- 皮膚:6.17
CAGE 大脳:1.76 小脳:- 脳幹:1.84 脳梁:2.49 松果体:0.36 末梢神経:- 脊柱:1.33 網膜:- 目:- 動脈:2.00 静脈:3.62 リンパ節:2.35 末梢血:- 脾臓:2.53 胸腺:5.21 骨髄:- 脂肪:2.03 骨:- 皮膚:-
RNA-seq 大脳:0.91 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.84 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.36 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.69 胎盤:5.36 前立腺:5.39 卵巣:5.32 精巣:5.33 心臓:6.05 骨格筋:5.92 食道:5.92 胃:6.78 腸:6.88 結腸:5.91 肝臓:5.55 肺:6.25 膀胱:- 腎臓:5.20 下垂体:5.27 甲状腺:5.70 副腎:5.84 膵臓:5.25 乳腺:5.81 唾液腺:5.64
CAGE 子宮:1.30 胎盤:1.14 前立腺:1.36 卵巣:1.33 精巣:1.49 心臓:2.39 骨格筋:1.42 食道:1.52 胃:- 腸:2.20 結腸:2.38     肝臓:1.16    肺:1.74 膀胱:1.42 腎臓:0.74 下垂体:0.66 甲状腺:1.27 副腎:- 膵臓:1.59 乳腺:1.80 唾液腺:0.83
RNA-seq 子宮:- 胎盤:- 前立腺:2.01 卵巣:1.66 精巣:2.27 心臓:1.26 骨格筋:0.95 食道:- 胃:- 腸:- 結腸:1.99     肝臓:1.48        肺:2.34    膀胱:- 腎臓:1.52 下垂体:- 甲状腺:1.31 副腎:3.05 膵臓:- 乳腺:1.73 唾液腺:-

IDs

Refseq ID NM_000022
Gene ID 100
Unigene ID -
Probe set ID 204639_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196839
GTEx ID ENSG00000196839

オーソログ対応遺伝子

マウス[1]  NM_007398
ラット[1]  NM_130399

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006154  adenosine catabolic process
GO:0007568  aging
GO:0007155  cell adhesion
GO:0046061  dATP catabolic process
GO:0006157  deoxyadenosine catabolic process
GO:0048566  embryonic gut development
GO:0002314  germinal center B cell differentiation
GO:0001821  histamine secretion
GO:0043103  hypoxanthine salvage
GO:0046103  inosine biosynthetic process
GO:0001889  liver development
GO:0048286  lung alveolus development
GO:0060169  negative regulation of adenosine receptor signaling pathway
GO:0042323  negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0050728  negative regulation of inflammatory response
GO:0002686  negative regulation of leukocyte migration
GO:0002906  negative regulation of mature B cell apoptosis
GO:0070256  negative regulation of mucus secretion
GO:0060407  negative regulation of penile erection
GO:0070244  negative regulation of thymocyte apoptosis
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0048541  Peyer's patch development
GO:0001890  placenta development
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0030890  positive regulation of B cell proliferation
GO:0050850  positive regulation of calcium-mediated signaling
GO:0002636  positive regulation of germinal center formation
GO:0010460  positive regulation of heart rate
GO:0045987  positive regulation of smooth muscle contraction
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0050862  positive regulation of T cell receptor signaling pathway
GO:0006144  purine base metabolic process
GO:0032261  purine nucleotide salvage
GO:0009168  purine ribonucleoside monophosphate biosynthetic process
GO:0043101  purine salvage
GO:0033632  regulation of cell-cell adhesion mediated by integrin
GO:0042542  response to hydrogen peroxide
GO:0001666  response to hypoxia
GO:0043278  response to morphine
GO:0042110  T cell activation
GO:0001829  trophectodermal cell differentiation
GO:0046111  xanthine biosynthetic process

Cellular Component

GO:0030054  cell junction
GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0060205  cytoplasmic membrane-bounded vesicle lumen
GO:0005829  cytosol
GO:0032839  dendrite cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0005764  lysosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004000  adenosine deaminase activity
GO:0005515  protein binding
GO:0001883  purine nucleoside binding
GO:0008270  zinc ion binding