cyclin-dependent kinase 2

 詳細情報を見る

同義遺伝子名

p33 protein kinase, Cell division protein kinase 2, p33(CDK2), cyclin-dependent kinase 2, CDK2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:11.90 小脳:- 脳幹:- 脳梁:175 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:17.60 動脈:30 静脈:66.60 リンパ節:40.40 末梢血:164 脾臓:94.50 胸腺:463.80 骨髄:- 脂肪:40.30 骨:51.20 皮膚:86.40
GeneChip 大脳:5.15 小脳:5.14 脳幹:5.14 脳梁:5.07 松果体:- 末梢神経:5.10 脊柱:4.92 網膜:- 目:- 動脈:5.37 静脈:5.43 リンパ節:5.26 末梢血:- 脾臓:5.05 胸腺:6.21 骨髄:5.67 脂肪:5.49 骨:- 皮膚:5.38
CAGE 大脳:1.62 小脳:- 脳幹:1.72 脳梁:1.62 松果体:1.15 末梢神経:- 脊柱:2.13 網膜:- 目:- 動脈:2.69 静脈:2.73 リンパ節:2.42 末梢血:- 脾臓:2.74 胸腺:3.73 骨髄:- 脂肪:2.65 骨:- 皮膚:-
RNA-seq 大脳:0.77 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.08 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.00 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:82 胎盤:131.10 前立腺:22.50 卵巣:149.10 精巣:4.30 心臓:51.10 骨格筋:- 食道:- 胃:- 腸:64.80 結腸:33.90     肝臓:31.70        肺:34.20    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.37 胎盤:5.52 前立腺:5.19 卵巣:5.36 精巣:5.22 心臓:5.39 骨格筋:5.21 食道:5.32 胃:5.22 腸:5.30 結腸:5.70 肝臓:5.24 肺:5.50 膀胱:- 腎臓:5.29 下垂体:5.11 甲状腺:4.95 副腎:5.16 膵臓:5.28 乳腺:5.10 唾液腺:5.39
CAGE 子宮:2.66 胎盤:4.04 前立腺:2.69 卵巣:2.74 精巣:2.35 心臓:2.53 骨格筋:2.28 食道:2.86 胃:- 腸:2.27 結腸:2.65     肝臓:2.91    肺:2.83 膀胱:3.07 腎臓:2.32 下垂体:1.71 甲状腺:2.45 副腎:- 膵臓:1.98 乳腺:2.19 唾液腺:1.95
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:1.47 精巣:0.94 心臓:0.50 骨格筋:0.30 食道:- 胃:- 腸:- 結腸:0.52     肝臓:0.27        肺:1.33    膀胱:- 腎臓:1.24 下垂体:- 甲状腺:0.51 副腎:0.17 膵臓:- 乳腺:0.89 唾液腺:-

詳細情報

IDs

Refseq ID NM_052827
Gene ID 1017
Unigene ID Hs.19192
Probe set ID 211804_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000123374
GTEx ID ENSG00000123374

オーソログ対応遺伝子

マウス[2]  NM_016756, NM_183417
ラット [0]  

染色体

12q13.2  [56,360,553  -  56,366,568]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0007596  blood coagulation
GO:0051301  cell division
GO:0051298  centrosome duplication
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0006281  DNA repair
GO:0006260  DNA replication
GO:0031571  G1/S DNA damage checkpoint
GO:0000082  G1/S transition of mitotic cell cycle
GO:0000085  G2 phase of mitotic cell cycle
GO:0000086  G2/M transition of mitotic cell cycle
GO:0016572  histone phosphorylation
GO:0007126  meiosis
GO:0007067  mitosis
GO:0000278  mitotic cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0032298  positive regulation of DNA replication initiation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006813  potassium ion transport
GO:0007265  Ras protein signal transduction
GO:0060968  regulation of gene silencing
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle

Cellular Component

GO:0015030  Cajal body
GO:0005813  centrosome
GO:0000781  chromosome, telomeric region
GO:0000793  condensed chromosome
GO:0000307  cyclin-dependent protein kinase holoenzyme complex
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005768  endosome
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex
GO:0000805  X chromosome
GO:0000806  Y chromosome

Molecular Function

GO:0005524  ATP binding
GO:0030332  cyclin binding
GO:0004693  cyclin-dependent protein kinase activity
GO:0035173  histone kinase activity
GO:0046872  metal ion binding
GO:0005515  protein binding