leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

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同義遺伝子名

LILRB1, CD85j antigen, ILT-2, ILT2, LIR1, MIR-7, MIR7, Immunoglobulin-like transcript 2, Leukocyte immunoglobulin-like receptor 1, Monocyte/macrophage immunoglobulin-like receptor 7, CD85j, LIR-1, CD85, CD85J

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.69 小脳:5.72 脳幹:5.78 脳梁:6 松果体:- 末梢神経:5.43 脊柱:5.85 網膜:- 目:- 動脈:5.79 静脈:5.85 リンパ節:6.21 末梢血:- 脾臓:6.56 胸腺:5.64 骨髄:6.66 脂肪:5.78 骨:- 皮膚:5.93
CAGE 大脳:1.24 小脳:- 脳幹:2.03 脳梁:2.15 松果体:0.82 末梢神経:- 脊柱:2.34 網膜:- 目:- 動脈:1.72 静脈:2.25 リンパ節:2.89 末梢血:- 脾臓:4.36 胸腺:1.01 骨髄:- 脂肪:1.60 骨:- 皮膚:-
RNA-seq 大脳:0.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.63 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.40 胎盤:5.58 前立腺:5.35 卵巣:5.63 精巣:5.24 心臓:5.79 骨格筋:5.80 食道:5.34 胃:5.59 腸:5.89 結腸:5.83 肝臓:5.88 肺:6.27 膀胱:- 腎臓:5.50 下垂体:5.55 甲状腺:5.29 副腎:5.62 膵臓:5.96 乳腺:5.38 唾液腺:5.66
CAGE 子宮:0.89 胎盤:1.90 前立腺:1.58 卵巣:1.16 精巣:0.57 心臓:1.17 骨格筋:0.42 食道:1.08 胃:- 腸:1.24 結腸:1.53     肝臓:1.81    肺:2.21 膀胱:1.15 腎臓:1.06 下垂体:0.86 甲状腺:0.49 副腎:- 膵臓:0.94 乳腺:1.36 唾液腺:1.00
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.75 精巣:0.00 心臓:0.22 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.36        肺:1.28    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.22 副腎:0.30 膵臓:- 乳腺:0.33 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0071222  cellular response to lipopolysaccharide
GO:0051607  defense response to virus
GO:0002774  Fc receptor mediated inhibitory signaling pathway
GO:0002767  immune response-inhibiting cell surface receptor signaling pathway
GO:0032609  interferon-gamma production
GO:0046636  negative regulation of alpha-beta T cell activation
GO:0051926  negative regulation of calcium ion transport
GO:0045786  negative regulation of cell cycle
GO:0002740  negative regulation of cytokine secretion during immune response
GO:0045806  negative regulation of endocytosis
GO:0045077  negative regulation of interferon-gamma biosynthetic process
GO:0032689  negative regulation of interferon-gamma production
GO:0032945  negative regulation of mononuclear cell proliferation
GO:0045953  negative regulation of natural killer cell mediated cytotoxicity
GO:0014063  negative regulation of serotonin secretion
GO:0001915  negative regulation of T cell mediated cytotoxicity
GO:0042130  negative regulation of T cell proliferation
GO:0042536  negative regulation of tumor necrosis factor biosynthetic process
GO:0043065  positive regulation of apoptosis
GO:0045919  positive regulation of cytolysis
GO:0002230  positive regulation of defense response to virus by host
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0031623  receptor internalization
GO:0050776  regulation of immune response
GO:0009615  response to virus
GO:0007165  signal transduction
GO:0002309  T cell proliferation during immune response

Cellular Component

GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0030107  HLA-A specific inhibitory MHC class I receptor activity
GO:0030109  HLA-B specific inhibitory MHC class I receptor activity
GO:0042288  MHC class I protein binding
GO:0032393  MHC class I receptor activity
GO:0042803  protein homodimerization activity
GO:0008157  protein phosphatase 1 binding
GO:0042169  SH2 domain binding