conserved helix-loop-helix ubiquitous kinase

同義遺伝子名

NFKBIKA, conserved helix-loop-helix ubiquitous kinase, IKKA, IKK-A, I kappa-B kinase alpha, CHUK, IKBKA, I-kappa-B kinase 1, IKK-alpha, IKK1, Nuclear factor NF-kappa-B inhibitor kinase alpha, IkBKA, Conserved helix-loop-helix ubiquitous kinase, TCF16, IkappaB kinase

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:20.10

小脳:25.20

脳幹:-

脳梁:29.20

松果体:-

末梢神経:30.70

脊柱:224.60

網膜:-

目:11.80

動脈:-

静脈:-

リンパ節:60.70

末梢血:-

脾臓:18.90

胸腺:25.80

骨髄:-

脂肪:-

骨:-

皮膚:28.80

GeneChip

大脳:4.93

小脳:4.84

脳幹:5.02

脳梁:5.38

松果体:-

末梢神経:5.22

脊柱:5.47

網膜:-

目:-

動脈:5.10

静脈:4.81

リンパ節:5.39

末梢血:-

脾臓:5.55

胸腺:6.23

骨髄:5.69

脂肪:5.38

骨:-

皮膚:5.36

CAGE

大脳:3.00

小脳:-

脳幹:3.19

脳梁:3.03

松果体:3.16

末梢神経:-

脊柱:3.38

網膜:-

目:-

動脈:2.85

静脈:3.03

リンパ節:3.13

末梢血:-

脾臓:3.29

胸腺:3.32

骨髄:-

脂肪:3.17

骨:-

皮膚:-

RNA-seq

大脳:2.76

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.89

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.94

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:36.40

前立腺:11.30

卵巣:-

精巣:17.30

心臓:12.80

骨格筋:-

食道:-

胃:-

腸:64.80

結腸:17

肝臓:-

肺:14.70

膀胱:-

腎臓:41.60

下垂体:-

甲状腺:-

副腎:-

膵臓:44.50

乳腺:37.20

唾液腺:-

GeneChip

子宮:5.29

胎盤:5.47

前立腺:5.62

卵巣:5.10

精巣:4.90

心臓:5.06

骨格筋:5.72

食道:5.32

胃:5.43

腸:5.22

結腸:4.59

肝臓:5.53

肺:5.48

膀胱:-

腎臓:5.85

下垂体:5.33

甲状腺:5.35

副腎:5.18

膵臓:4.71

乳腺:5.33

唾液腺:5.23

CAGE

子宮:3.00

胎盤:3.02

前立腺:2.85

卵巣:2.89

精巣:2.99

心臓:3.07

骨格筋:3.13

食道:2.80

胃:-

腸:3.40

結腸:2.82

肝臓:3.79

肺:3.25

膀胱:3.00

腎臓:3.59

下垂体:3.25

甲状腺:2.92

副腎:-

膵臓:2.98

乳腺:3.16

唾液腺:3.05

RNA-seq

子宮:-

胎盤:-

前立腺:2.86

卵巣:3.33

精巣:2.96

心臓:2.52

骨格筋:2.85

食道:-

胃:-

腸:-

結腸:2.98

肝臓:3.17

肺:2.72

膀胱:-

腎臓:3.74

下垂体:-

甲状腺:3.50

副腎:2.86

膵臓:-

乳腺:3.06

唾液腺:-

IDs

Refseq ID	NM_001278
Gene ID	1147
Unigene ID	Hs.198998
Probe set ID	209666_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000213341
GTEx ID	ENSG00000213341

オーソログ対応遺伝子

マウス[4]	NM_001162410, NM_007700
ラット[1]	NM_001107588, NM_007700

染色体

10q24.31 [101,948,055 - 101,989,376]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0007252	I-kappaB phosphorylation
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0007595	lactation
GO:0060749	mammary gland alveolus development
GO:0033598	mammary gland epithelial cell proliferation
GO:0002011	morphogenesis of an epithelial sheet
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0048011	nerve growth factor receptor signaling pathway
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0042475	odontogenesis of dentine-containing tooth
GO:0030316	osteoclast differentiation
GO:0048015	phosphoinositide-mediated signaling
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0032481	positive regulation of type I interferon production
GO:0006468	protein amino acid phosphorylation
GO:0043200	response to amino acid stimulus
GO:0042493	response to drug
GO:0033194	response to hydroperoxide
GO:0032496	response to lipopolysaccharide
GO:0009636	response to toxin
GO:0009615	response to virus
GO:0007266	Rho protein signal transduction
GO:0003009	skeletal muscle contraction
GO:0051146	striated muscle cell differentiation
GO:0050852	T cell receptor signaling pathway
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0008385	IkappaB kinase complex
GO:0009898	internal side of plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0005730	nucleolus
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0042802	identical protein binding
GO:0008384	IkappaB kinase activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0004672	protein kinase activity

conserved helix-loop-helix ubiquitous kinase

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function