c-src tyrosine kinase

詳細情報を見る

同義遺伝子名

Protein-tyrosine kinase CYL, C-SRC kinase, c-src tyrosine kinase, CSK, MGC117393, Tyrosine-protein kinase CSK

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:22.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:58.80 動脈:60 静脈:- リンパ節:252.80 末梢血:255.10 脾臓:378.10 胸腺:103.10 骨髄:98.40 脂肪:- 骨:38.40 皮膚:28.80
GeneChip 大脳:6.76 小脳:6.99 脳幹:7.05 脳梁:7.14 松果体:- 末梢神経:6.80 脊柱:7.13 網膜:- 目:- 動脈:6.81 静脈:6.67 リンパ節:9.01 末梢血:- 脾臓:9.05 胸腺:8.15 骨髄:7.74 脂肪:7 骨:- 皮膚:7.11
CAGE 大脳:4.02 小脳:- 脳幹:4.18 脳梁:4.18 松果体:4.18 末梢神経:- 脊柱:4.20 網膜:- 目:- 動脈:3.80 静脈:5.13 リンパ節:5.52 末梢血:- 脾臓:5.53 胸腺:5.61 骨髄:- 脂肪:3.98 骨:- 皮膚:-
RNA-seq 大脳:2.64 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:5.28 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.58 骨:- 皮膚:-
EST 子宮:- 胎盤:21.90 前立腺:33.80 卵巣:37.30 精巣:34.60 心臓:12.80 骨格筋:- 食道:- 胃:21.20 腸:97.20 結腸:84.80     肝臓:21.10        肺:48.90    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:8.90 乳腺:46.50 唾液腺:328.40
GeneChip 子宮:6.83 胎盤:6.53 前立腺:6.63 卵巣:6.86 精巣:6.92 心臓:6.97 骨格筋:6.41 食道:8.46 胃:7.50 腸:7.17 結腸:7.74 肝臓:7.35 肺:7.57 膀胱:- 腎臓:6.95 下垂体:6.84 甲状腺:7.02 副腎:6.98 膵臓:6.39 乳腺:7.41 唾液腺:7.33
CAGE 子宮:4.02 胎盤:3.82 前立腺:4.04 卵巣:3.97 精巣:4.04 心臓:4.00 骨格筋:2.97 食道:4.73 胃:- 腸:4.64 結腸:4.41     肝臓:4.60    肺:4.38 膀胱:3.62 腎臓:3.80 下垂体:3.67 甲状腺:3.76 副腎:- 膵臓:3.59 乳腺:4.28 唾液腺:4.18
RNA-seq 子宮:- 胎盤:- 前立腺:3.04 卵巣:4.00 精巣:3.91 心臓:2.44 骨格筋:1.96 食道:- 胃:- 腸:- 結腸:2.91     肝臓:3.63        肺:3.52    膀胱:- 腎臓:3.14 下垂体:- 甲状腺:2.72 副腎:5.69 膵臓:- 乳腺:3.32 唾液腺:-

IDs

Refseq ID NM_001127190
Gene ID 1445
Unigene ID Hs.77793
Probe set ID 202329_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103653
GTEx ID ENSG00000103653

オーソログ対応遺伝子

マウス[1]  NM_007783
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1371489
1377109
1720539
1945408
1985196
7511113
7512694
7513429
7515063
7529872
7544435
7678701
7683131
8125298
8262983
8612628
8619474
8621646
8631894
8890164
9110174
9148770
9172452
9208935
9221755
9553134
9582365
9621077
9624175
9794236
9858471
10026153
10037694
10210201
10733577
10753943
10790433
10801129
10918051
11035005
11084024
11149930
11158295
11181701
11278940
11433379
11602604
11685249
11695992
11724538
11724572
11805080
11834728
11872746
11875070
11971983
11976726
12048194
12052863
12387813
12400005
12402152
12468645
12473651
12477932
12485116
12547828
12588871
12645577
12665526
12686554
12697812
12707358
12782282
12794155
12871315
14561750
14610046
14657361
14702039
14707140
14993273
15144186
15175272
15474475
15489334
15574420
15623523
15743820
15749833
15861137
15890649
15961079
16002086
16005629
16135530
16380958
16439366
16532030
16636672
16729043
16740711
16858407
16859511
16964398
17012367
17018524
17056000
17060931
17125257
17132222
17137590
17143285
17192257
17223712
17325034
17329398
17491594
17525734
17691821
17692281
17936276
17936985
17951261
18029348
18039857
18255255
18258597
18268019
18332219
18445593
18482983
18614016
19018258
19056867
19147678
19167335
19198071
19262695
19288857
19322201
19380743
19430479
19430483
19464057
19520085
19561643
19565264
19757166
19818398
19887846
19888460
19913121
19960030
20010872
20056178
20360068
20414254
20434462
20453000
20479155
20542020
20628086
21045733
21139048
21156787
21245141
21367918
21490707
21513978
21538482
21562048
21706016
21782877
21890473
21909110
21909115
22038627
22407130
22505724
22521508
22959498
23042117
23108098
23359562
23383002
23383273
23455922
23671128
23740937
23804206
23824743
23923048
23946333
24015220
24103328
24180592
24250222
24300854
24778252
24797263
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0034332  adherens junction organization
GO:0007596  blood coagulation
GO:0007420  brain development
GO:0071375  cellular response to peptide hormone stimulus
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0045779  negative regulation of bone resorption
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0042997  negative regulation of Golgi to plasma membrane protein transport
GO:0032715  negative regulation of interleukin-6 production
GO:0033673  negative regulation of kinase activity
GO:0010989  negative regulation of low-density lipoprotein particle clearance
GO:0050765  negative regulation of phagocytosis
GO:0048709  oligodendrocyte differentiation
GO:0030168  platelet activation
GO:0043406  positive regulation of MAP kinase activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0060368  regulation of Fc receptor mediated stimulatory signaling pathway
GO:0031295  T cell costimulation
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0005911  cell-cell junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0070064  proline-rich region binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0019903  protein phosphatase binding
GO:0004713  protein tyrosine kinase activity