connective tissue growth factor

詳細情報を見る

同義遺伝子名

MGC102839, connective tissue growth factor, IGFBP8, Hypertrophic chondrocyte-specific protein 24, HCS24, CTGF, CCN2, Connective tissue growth factor precursor, NOV2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.53 小脳:4.47 脳幹:5.45 脳梁:5.56 松果体:- 末梢神経:8.30 脊柱:5.86 網膜:- 目:- 動脈:8.76 静脈:9.66 リンパ節:6.53 末梢血:- 脾臓:9.54 胸腺:5.90 骨髄:6.04 脂肪:8.19 骨:- 皮膚:7.58
CAGE 大脳:3.60 小脳:- 脳幹:3.45 脳梁:3.89 松果体:3.82 末梢神経:- 脊柱:3.79 網膜:- 目:- 動脈:7.57 静脈:5.37 リンパ節:4.99 末梢血:- 脾臓:6.97 胸腺:3.48 骨髄:- 脂肪:5.51 骨:- 皮膚:-
RNA-seq 大脳:4.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:5.14 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:6.01 骨:- 皮膚:-
EST nodata
GeneChip 子宮:9.12 胎盤:8.49 前立腺:8.54 卵巣:8.76 精巣:6.43 心臓:8.04 骨格筋:6.32 食道:6.90 胃:7.87 腸:8.28 結腸:7.61 肝臓:5.74 肺:9.21 膀胱:- 腎臓:8.08 下垂体:5.80 甲状腺:8.80 副腎:7.85 膵臓:7.34 乳腺:8.96 唾液腺:7.77
CAGE 子宮:6.42 胎盤:5.56 前立腺:5.73 卵巣:5.30 精巣:5.15 心臓:5.69 骨格筋:5.08 食道:5.13 胃:- 腸:5.21 結腸:4.59     肝臓:4.63    肺:5.75 膀胱:5.76 腎臓:6.24 下垂体:3.70 甲状腺:5.38 副腎:- 膵臓:3.82 乳腺:5.29 唾液腺:5.02
RNA-seq 子宮:- 胎盤:- 前立腺:6.43 卵巣:5.34 精巣:6.60 心臓:5.47 骨格筋:3.51 食道:- 胃:- 腸:- 結腸:6.42     肝臓:2.39        肺:6.47    膀胱:- 腎臓:8.13 下垂体:- 甲状腺:7.06 副腎:6.24 膵臓:- 乳腺:6.79 唾液腺:-

IDs

Refseq ID NM_001901
Gene ID 1490
Unigene ID -
Probe set ID 209101_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118523
GTEx ID ENSG00000118523

オーソログ対応遺伝子

マウス[1]  NM_010217
ラット[1]  NM_022266

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1293144
1334251
1654338
1925598
9054739
9242708
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10204117
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0001502  cartilage condensation
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0007160  cell-matrix adhesion
GO:0044255  cellular lipid metabolic process
GO:0060401  cytosolic calcium ion transport
GO:0006260  DNA replication
GO:0008544  epidermis development
GO:0070278  extracellular matrix constituent secretion
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0010467  gene expression
GO:0007229  integrin-mediated signaling pathway
GO:0030324  lung development
GO:0010629  negative regulation of gene expression
GO:0010260  organ senescence
GO:0001503  ossification
GO:0060452  positive regulation of cardiac muscle contraction
GO:0043280  positive regulation of caspase activity
GO:0050867  positive regulation of cell activation
GO:0010942  positive regulation of cell death
GO:0045597  positive regulation of cell differentiation
GO:0008284  positive regulation of cell proliferation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0070318  positive regulation of G0 to G1 transition
GO:0010628  positive regulation of gene expression
GO:0046330  positive regulation of JNK cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051496  positive regulation of stress fiber formation
GO:0001558  regulation of cell growth
GO:0032330  regulation of chondrocyte differentiation
GO:0043200  response to amino acid stimulus
GO:0034059  response to anoxia
GO:0032355  response to estradiol stimulus
GO:0070542  response to fatty acid
GO:0009749  response to glucose stimulus
GO:0051385  response to mineralocorticoid stimulus
GO:0043434  response to peptide hormone stimulus
GO:0009611  response to wounding
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005938  cell cortex
GO:0005801  cis-Golgi network
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0001968  fibronectin binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0005520  insulin-like growth factor binding
GO:0005178  integrin binding