catenin (cadherin-associated protein), beta 1, 88kDa

詳細情報を見る

同義遺伝子名

CTNNB, OK/SW-cl.35, Beta-catenin, CTNNB1, PRO2286, Catenin beta-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:212.10 小脳:1221.60 脳幹:- 脳梁:262.50 松果体:- 末梢神経:245.40 脊柱:112.30 網膜:237.30 目:111.70 動脈:329.70 静脈:333.20 リンパ節:40.40 末梢血:109.30 脾臓:132.30 胸腺:566.90 骨髄:39.40 脂肪:- 骨:217.50 皮膚:307.20
GeneChip 大脳:8.32 小脳:9.03 脳幹:8.17 脳梁:8.54 松果体:- 末梢神経:8.27 脊柱:8.83 網膜:- 目:- 動脈:8.11 静脈:8.62 リンパ節:8 末梢血:- 脾臓:8.26 胸腺:8.67 骨髄:7.63 脂肪:8.21 骨:- 皮膚:8.22
CAGE 大脳:5.29 小脳:- 脳幹:5.09 脳梁:5.51 松果体:5.13 末梢神経:- 脊柱:5.33 網膜:- 目:- 動脈:5.28 静脈:5.08 リンパ節:4.96 末梢血:- 脾臓:5.06 胸腺:4.96 骨髄:- 脂肪:5.44 骨:- 皮膚:-
RNA-seq 大脳:3.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.19 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.40 骨:- 皮膚:-
EST 子宮:455.70 胎盤:123.90 前立腺:191.50 卵巣:223.60 精巣:125.50 心臓:102.20 骨格筋:80.40 食道:- 胃:127.50 腸:- 結腸:797.10     肝臓:63.30        肺:459.40    膀胱:628.10 腎臓:72.80 下垂体:116 甲状腺:- 副腎:203.10 膵臓:35.60 乳腺:446.10 唾液腺:328.40
GeneChip 子宮:9.11 胎盤:8.71 前立腺:9.07 卵巣:9.07 精巣:7.87 心臓:8.32 骨格筋:7.24 食道:8.17 胃:7.95 腸:8.44 結腸:8.44 肝臓:7.79 肺:8.83 膀胱:- 腎臓:8.21 下垂体:8.20 甲状腺:8.79 副腎:8.57 膵臓:7.81 乳腺:8.62 唾液腺:8.14
CAGE 子宮:5.77 胎盤:5.77 前立腺:5.43 卵巣:5.88 精巣:5.03 心臓:5.37 骨格筋:4.79 食道:5.18 胃:- 腸:5.67 結腸:5.19     肝臓:5.15    肺:5.30 膀胱:5.31 腎臓:5.26 下垂体:5.16 甲状腺:5.50 副腎:- 膵臓:5.02 乳腺:5.07 唾液腺:5.32
RNA-seq 子宮:- 胎盤:- 前立腺:4.24 卵巣:4.52 精巣:3.78 心臓:3.66 骨格筋:2.91 食道:- 胃:- 腸:- 結腸:3.40     肝臓:3.07        肺:5.21    膀胱:- 腎臓:3.30 下垂体:- 甲状腺:3.91 副腎:3.79 膵臓:- 乳腺:3.34 唾液腺:-

IDs

Refseq ID NM_001098209
Gene ID 1499
Unigene ID Hs.476018
Probe set ID 201533_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000168036
GTEx ID ENSG00000168036

オーソログ対応遺伝子

マウス[6]  NM_001165902, NM_007614
ラット[1]  NM_053357, NM_007614

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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24798214

遺伝子オントロジー  (GO ID)

Biological Process

GO:0034333  adherens junction assembly
GO:0030521  androgen receptor signaling pathway
GO:0009948  anterior/posterior axis specification
GO:0006915  apoptosis
GO:0045453  bone resorption
GO:0060441  branching involved in lung morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0003136  canonical Wnt receptor signaling pathway involved in heart induction
GO:0007155  cell adhesion
GO:0001708  cell fate specification
GO:0048469  cell maturation
GO:0006921  cell structure disassembly during apoptosis
GO:0016337  cell-cell adhesion
GO:0007160  cell-matrix adhesion
GO:0071363  cellular response to growth factor stimulus
GO:0022009  central nervous system vasculogenesis
GO:0007016  cytoskeletal anchoring at plasma membrane
GO:0048262  determination of dorsal/ventral asymmetry
GO:0009950  dorsal/ventral axis specification
GO:0007398  ectoderm development
GO:0000578  embryonic axis specification
GO:0042733  embryonic digit morphogenesis
GO:0048617  embryonic foregut morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035050  embryonic heart tube development
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0001711  endodermal cell fate commitment
GO:0060742  epithelial cell differentiation involved in prostate gland development
GO:0001837  epithelial to mesenchymal transition
GO:0060066  fallopian tube development
GO:0030900  forebrain development
GO:0001702  gastrulation with mouth forming second
GO:0035112  genitalia morphogenesis
GO:0007403  glial cell fate determination
GO:0035315  hair cell differentiation
GO:0031069  hair follicle morphogenesis
GO:0060789  hair follicle placode formation
GO:0030902  hindbrain development
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0002089  lens morphogenesis in camera-type eye
GO:0001889  liver development
GO:0060479  lung cell differentiation
GO:0060492  lung induction
GO:0060484  lung-associated mesenchyme development
GO:0030539  male genitalia development
GO:0060916  mesenchymal cell proliferation involved in lung development
GO:0003337  mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0007494  midgut development
GO:0042692  muscle cell differentiation
GO:0045445  myoblast differentiation
GO:0008285  negative regulation of cell proliferation
GO:0032331  negative regulation of chondrocyte differentiation
GO:0048715  negative regulation of oligodendrocyte differentiation
GO:0045671  negative regulation of osteoclast differentiation
GO:0033234  negative regulation of protein sumoylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001840  neural plate development
GO:0001764  neuron migration
GO:0042475  odontogenesis of dentine-containing tooth
GO:0048599  oocyte development
GO:0030316  osteoclast differentiation
GO:0031016  pancreas development
GO:0001569  patterning of blood vessels
GO:0043065  positive regulation of apoptosis
GO:0045603  positive regulation of endothelial cell differentiation
GO:0060769  positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0045743  positive regulation of fibroblast growth factor receptor signaling pathway
GO:0010909  positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0051149  positive regulation of muscle cell differentiation
GO:0002052  positive regulation of neuroblast proliferation
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032481  positive regulation of type I interferon production
GO:0051291  protein heterooligomerization
GO:0034394  protein localization at cell surface
GO:0009954  proximal/distal pattern formation
GO:0045765  regulation of angiogenesis
GO:0030997  regulation of centriole-centriole cohesion
GO:0070602  regulation of centromeric sister chromatid cohesion
GO:0048145  regulation of fibroblast proliferation
GO:0031641  regulation of myelination
GO:0003266  regulation of second heart field cardioblast proliferation
GO:0048660  regulation of smooth muscle cell proliferation
GO:0042129  regulation of T cell proliferation
GO:0046686  response to cadmium ion
GO:0034097  response to cytokine stimulus
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0014010  Schwann cell proliferation
GO:0051145  smooth muscle cell differentiation
GO:0050808  synapse organization
GO:0048489  synaptic vesicle transport
GO:0033077  T cell differentiation in the thymus
GO:0048538  thymus development
GO:0043587  tongue morphogenesis
GO:0060440  trachea formation
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005912  adherens junction
GO:0045177  apical part of cell
GO:0016323  basolateral plasma membrane
GO:0030877  beta-catenin destruction complex
GO:0070369  beta-catenin-TCF7L2 complex
GO:0016342  catenin complex
GO:0005938  cell cortex
GO:0030054  cell junction
GO:0005913  cell-cell adherens junction
GO:0005911  cell-cell junction
GO:0005924  cell-substrate adherens junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0030057  desmosome
GO:0005916  fascia adherens
GO:0009898  internal side of plasma membrane
GO:0030027  lamellipodium
GO:0016328  lateral plasma membrane
GO:0016020  membrane
GO:0031528  microvillus membrane
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0032993  protein-DNA complex
GO:0034750  Scrib-APC-beta-catenin complex
GO:0000922  spindle pole
GO:0045202  synapse
GO:0005667  transcription factor complex
GO:0030018  Z disc
GO:0005915  zonula adherens

Molecular Function

GO:0045294  alpha-catenin binding
GO:0050681  androgen receptor binding
GO:0045296  cadherin binding
GO:0003682  chromatin binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0019899  enzyme binding
GO:0030331  estrogen receptor binding
GO:0070411  I-SMAD binding
GO:0035255  ionotropic glutamate receptor binding
GO:0019900  kinase binding
GO:0035257  nuclear hormone receptor binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0032403  protein complex binding
GO:0019901  protein kinase binding
GO:0019903  protein phosphatase binding
GO:0070412  R-SMAD binding
GO:0004871  signal transducer activity
GO:0046332  SMAD binding
GO:0005198  structural molecule activity
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding