cytochrome P450, family 1, subfamily A, polypeptide 2

詳細情報を見る

同義遺伝子名

CYP1A2, P450 4, P3-450, CP12, P450(PA), P450-P3, Cytochrome P450 1A2, CYPIA2, subfamily I (aromatic compound-inducible), P(3)450

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:69.90 小脳:25.20 脳幹:- 脳梁:58.30 松果体:148.30 末梢神経:92 脊柱:- 網膜:118.60 目:64.60 動脈:- 静脈:- リンパ節:111.20 末梢血:18.20 脾臓:113.40 胸腺:25.80 骨髄:78.70 脂肪:40.30 骨:38.40 皮膚:172.80
GeneChip 大脳:4.89 小脳:4.78 脳幹:4.91 脳梁:4.63 松果体:- 末梢神経:4.79 脊柱:4.73 網膜:- 目:- 動脈:4.97 静脈:4.99 リンパ節:4.78 末梢血:- 脾臓:4.40 胸腺:4.61 骨髄:4.86 脂肪:4.96 骨:- 皮膚:5.16
CAGE 大脳:0.13 小脳:- 脳幹:0 脳梁:0.13 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:0.18 リンパ節:0 末梢血:- 脾臓:0 胸腺:0.06 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.05 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.03 骨:- 皮膚:-
EST 子宮:36.50 胎盤:196.70 前立腺:67.60 卵巣:521.70 精巣:17.30 心臓:114.90 骨格筋:100.50 食道:- 胃:85 腸:- 結腸:42.40     肝臓:126.70        肺:48.90    膀胱:251.20 腎臓:83.20 下垂体:116 甲状腺:- 副腎:- 膵臓:80 乳腺:204.40 唾液腺:-
GeneChip 子宮:4.72 胎盤:4.59 前立腺:4.68 卵巣:4.78 精巣:4.70 心臓:4.76 骨格筋:5.11 食道:4.84 胃:4.64 腸:4.93 結腸:4.87 肝臓:9.63 肺:4.92 膀胱:- 腎臓:4.59 下垂体:5 甲状腺:4.83 副腎:4.70 膵臓:5.42 乳腺:4.71 唾液腺:4.82
CAGE 子宮:0 胎盤:0 前立腺:0 卵巣:0 精巣:0 心臓:0.13 骨格筋:0.05 食道:0 胃:- 腸:0.07 結腸:0.35     肝臓:5.91    肺:0 膀胱:0 腎臓:0.08 下垂体:0 甲状腺:0.17 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.04 卵巣:0.00 精巣:0.04 心臓:0.00 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:3.10        肺:0.44    膀胱:- 腎臓:0.04 下垂体:- 甲状腺:1.61 副腎:0.00 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_000761
Gene ID 1544
Unigene ID Hs.136102
Probe set ID 207609_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000140505
GTEx ID ENSG00000140505

オーソログ対応遺伝子

マウス[1]  NM_009993
ラット[1]  NM_009993

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

2575218
2813353
3000715
3462722
3517618
3681487
3755823
8095225
8287062
8553685
8573198
8694864
9398194
9598815
9797707
9884316
9890157
10463577
10493258
10791558
11153915
11186132
11207026
11275366
11393588
11470995
11496364
11501059
11507974
11511187
11749050
11763009
11782366
11791895
11817502
11943609
12067576
12147246
12181774
12419832
12445029
12445035
12477932
12484238
12534642
12566081
12569554
12618594
12630986
12663508
12692107
12732846
12790158
12851801
12900870
12920202
12925300
12943470
14563787
14640293
14648207
14695651
14714565
14723376
14976127
15039299
15110095
15128046
15241822
15299091
15319333
15327587
15349722
15363478
15382051
15387446
15466009
15469410
15489334
15505641
15519301
15564895
15643613
15680923
15734958
15763632
15770072
15774926
15849225
15890241
15901993
15941966
15949157
15987714
15996939
16006997
16048566
16103451
16130011
16153396
16157215
16172230
16188490
16204462
16307269
16324277
16385402
16401082
16402077
16402549
16406813
16426572
16471212
16495781
16505155
16522833
16538170
16538176
16609368
16636061
16740387
16772608
16775389
16782969
16800822
16864595
16882880
16933202
16969362
16985026
16985250
17065585
17164366
17178267
17191090
17259654
17295924
17311915
17345072
17363580
17370067
17372239
17418993
17429315
17477782
17498780
17503978
17507615
17507624
17509724
17564586
17603224
17603900
17611010
17615053
17616786
17627011
17635176
17688403
17695473
17823232
17823234
17852022
17900275
18052847
18075470
18077912
18159984
18180754
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18200441
18223460
18231117
18268115
18318428
18356043
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18455494
18466106
18490497
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18499698
18510611
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18551037
18569587
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18632753
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18751408
18759349
18784359
18798002
18801337
18813311
18825963
18840375
18850169
18936436
18941913
18990750
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18996102
19000940
19026171
19029318
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19276377
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19290787
19307236
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19338043
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19343046
19356113
19414633
19415745
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19430483
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19450128
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19452301
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19479063
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19534587
19569730
19571439
19574343
19575027
19576320
19583676
19593158
19593168
19605743
19636338
19643819
19651758
19666078
19682433
19692168
19751749
19776291
19789190
19806921
19822571
19823875
19843669
19860743
19913121
19926050
19956635
19961320
20029944
20043572
20047124
20054636
20080081
20118554
20125119
20131310
20136364
20147896
20163457
20173083
20175915
20213484
20214802
20218903
20304699
20375710
20381444
20389299
20390257
20403997
20437850
20453000
20505544
20529763
20559687
20583967
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20602615
20628086
20634197
20634891
20641098
20652353
20656072
20663043
20691427
20701904
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20797314
20806393
20829355
20853468
20881513
20930417
20933493
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21072184
21081473
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21148426
21210738
21262253
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21329464
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21480221
21490707
21505853
21598960
21825116
21876539
21929532
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22086975
22141270
22228482
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22258279
22336631
22426036
22448362
22466345
22492992
22628494
22648710
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22785257
22823064
22854411
22855999
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22949628
23081704
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23133610
23138776
23157985
23167834
23278694
23292087
23353840
23462460
23492908
23492909
23601795
23603339
23628800
23859573
23876819
23949201
23951174
24099317
24293373
24318358
24443269
24514875

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009820  alkaloid metabolic process
GO:0019369  arachidonic acid metabolic process
GO:0045333  cellular respiration
GO:0071276  cellular response to cadmium ion
GO:0018894  dibenzo-p-dioxin metabolic process
GO:0042737  drug catabolic process
GO:0017144  drug metabolic process
GO:0019373  epoxygenase P450 pathway
GO:0042738  exogenous drug catabolic process
GO:0046483  heterocycle metabolic process
GO:0050665  hydrogen peroxide biosynthetic process
GO:0030324  lung development
GO:0032259  methylation
GO:0032787  monocarboxylic acid metabolic process
GO:0016098  monoterpenoid metabolic process
GO:0055114  oxidation reduction
GO:0070989  oxidative demethylation
GO:0006778  porphyrin metabolic process
GO:0009791  post-embryonic development
GO:0010468  regulation of gene expression
GO:0032355  response to estradiol stimulus
GO:0032496  response to lipopolysaccharide
GO:0006950  response to stress
GO:0006706  steroid catabolic process
GO:0009403  toxin biosynthetic process
GO:0006805  xenobiotic metabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0043231  intracellular membrane-bounded organelle

Molecular Function

GO:0070330  aromatase activity
GO:0034875  caffeine oxidase activity
GO:0032451  demethylase activity
GO:0009055  electron carrier activity
GO:0019899  enzyme binding
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016712  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen