dystrophin

詳細情報を見る

同義遺伝子名

Dystrophin, DXS272, DXS269, DXS230, includes DXS142, DXS268, DXS270, DXS239, DXS142, CMD3B, DMD, DXS206, DXS164, BMD

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:109 小脳:88.20 脳幹:- 脳梁:29.20 松果体:- 末梢神経:429.40 脊柱:673.80 網膜:711.80 目:199.80 動脈:- 静脈:- リンパ節:30.30 末梢血:- 脾臓:94.50 胸腺:25.80 骨髄:- 脂肪:161.30 骨:25.60 皮膚:91.20
GeneChip 大脳:6.51 小脳:6 脳幹:6.16 脳梁:6.50 松果体:- 末梢神経:9.26 脊柱:6.71 網膜:- 目:- 動脈:7.51 静脈:8.08 リンパ節:4.94 末梢血:- 脾臓:3.71 胸腺:4.22 骨髄:4.18 脂肪:6.98 骨:- 皮膚:6.55
CAGE 大脳:3.98 小脳:- 脳幹:4.01 脳梁:3.83 松果体:4.90 末梢神経:- 脊柱:3.91 網膜:- 目:- 動脈:4.64 静脈:3.55 リンパ節:2.58 末梢血:- 脾臓:2.20 胸腺:1.62 骨髄:- 脂肪:4.85 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.16 骨:- 皮膚:-
EST 子宮:100.20 胎盤:65.60 前立腺:146.40 卵巣:149.10 精巣:77.90 心臓:153.30 骨格筋:522.40 食道:- 胃:127.50 腸:97.20 結腸:76.30     肝臓:126.70        肺:83.10    膀胱:- 腎臓:31.20 下垂体:116 甲状腺:- 副腎:101.60 膵臓:106.70 乳腺:27.90 唾液腺:-
GeneChip 子宮:7 胎盤:6.23 前立腺:7.26 卵巣:7.76 精巣:5.14 心臓:8.07 骨格筋:9.19 食道:6.22 胃:7.28 腸:7.66 結腸:6.22 肝臓:7.76 肺:5.36 膀胱:- 腎臓:4.97 下垂体:5.41 甲状腺:6.07 副腎:7.14 膵臓:7.35 乳腺:7.03 唾液腺:7.88
CAGE 子宮:4.96 胎盤:3.14 前立腺:4.60 卵巣:4.30 精巣:3.29 心臓:4.77 骨格筋:5.53 食道:4.43 胃:- 腸:3.59 結腸:4.20     肝臓:3.90    肺:3.42 膀胱:5.30 腎臓:2.87 下垂体:3.20 甲状腺:3.45 副腎:- 膵臓:4.53 乳腺:3.97 唾液腺:4.68
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.01 精巣:0.22 心臓:0.00 骨格筋:1.59 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.00        肺:0.00    膀胱:- 腎臓:0 下垂体:- 甲状腺:0.18 副腎:0.07 膵臓:- 乳腺:0.13 唾液腺:-

IDs

Refseq ID NM_004013
Gene ID 1756
Unigene ID Hs.495912
Probe set ID 203881_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198947
GTEx ID ENSG00000198947

オーソログ対応遺伝子

マウス[4]  NM_007868
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1307251
1307253
1319059
1377655
1380160
1383546
1483053
1505985
1513469
1544421
1549596
1601417
1632439
1757094
1824797
1889805
1918370
1996328
2071150
2176467
2261642
2403634
2406613
2407739
2569720
2648158
2668885
2677830
2825128
2909892
3055295
3205741
3282674
3287171
3346018
3428261
3607877
3659917
3773991
3955860
7545544
7581396
7592992
7633443
7635962
7649554
7795584
7825571
7844150
7849724
7881286
7890602
7890770
7951253
7981590
7981690
8045556
8078878
8083345
8123157
8160755
8199594
8277968
8279470
8282811
8301652
8314593
8322822
8358174
8361506
8387534
8401537
8401582
8499922
8513330
8518789
8541829
8566960
8576247
8789442
8817332
8950674
9119397
9170407
9339369
9356463
9395493
9410897
9412493
9419360
9461390
9683584
9701558
9813236
9851445
10227401
10355629
10545507
10573008
10747910
10767429
10801490
10867799
10932245
11039581
11076863
11259305
11352924
11381192
11430802
11571312
11717465
11726549
11741599
11795488
11796130
11861579
11882782
11917091
11922612
11997265
12031623
12062429
12107815
12140183
12189167
12206800
12354438
12359139
12370193
12376554
12376747
12389738
12398834
12467728
12477932
12480947
12522557
12596052
12606026
12632325
12655282
12659812
12754415
12754707
12757471
12833401
12920092
14513410
14514278
14556187
14559354
14600269
14636778
14652441
14659407
15024025
15149856
15174051
15528988
15637982
15643612
15655674
15723292
15772651
16000376
16094384
16133659
16246949
16276108
16286242
16286249
16295426
16331671
16344560
16380627
16439510
16461336
16496225
16524176
16569668
16710609
16716778
16777071
16803572
16807118
16824516
16883524
16883579
16891620
16917894
16935300
16936400
17043677
17145200
17150596
17166095
17267499
17285139
17314512
17385798
17428346
17487735
17487865
17503325
17579806
17620599
17680544
17767400
17826093
17981813
17993586
17997718
18029348
18031759
18039686
18054699
18059005
18083704
18160999
18253029
18261477
18353051
18445268
18468998
18570328
18583217
18589007
18639760
18646563
18652600
18653336
18752307
18799475
18853462
18935728
18957474
18957722
18971620
18974567
19001018
19009915
19012301
19027585
19040728
19074751
19084397
19109891
19158079
19158820
19173203
19194174
19198614
19206170
19230662
19379759
19392646
19409785
19449031
19602481
19609279
19687056
19783145
19793655
19907931
19913121
19927354
19937601
19945424
19959795
20019182
20031633
20098710
20301298
20301486
20373002
20381484
20399196
20434517
20485447
20516809
20625423
20628086
20630757
20646909
20696926
20811636
20847377
20889312
20936779
21109441
21139048
21151598
21164104
21212803
21305657
21396098
21399986
21402533
21507246
21515508
21523654
21624465
21712383
21832049
21851881
21854195
21890473
21906983
21963094
21972111
21988832
22006698
22041458
22090376
22092019
22105192
22234188
22234189
22275054
22379338
22425969
22453924
22455600
22505724
22538063
22616200
22750404
22876130
22894145
22937058
22939629
22985905
22987438
23000965
23028937
23199925
23299919
23395799
23438214
23588064
23650001
23829870
23890933
23900271
24014171
24063785
24213305
24225992

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060048  cardiac muscle contraction
GO:0043623  cellular protein complex assembly
GO:0034613  cellular protein localization
GO:0008065  establishment of blood-nerve barrier
GO:0060857  establishment of glial blood-brain barrier
GO:0030198  extracellular matrix organization
GO:0048747  muscle fiber development
GO:0030049  muscle filament sliding
GO:0046716  muscle homeostasis
GO:0007517  muscle organ development
GO:0014904  myotube cell development
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0045213  neurotransmitter receptor metabolic process
GO:0051647  nucleus localization
GO:0021629  olfactory nerve structural organization
GO:0043043  peptide biosynthetic process
GO:0001954  positive regulation of cell-matrix adhesion
GO:0045666  positive regulation of neuron differentiation
GO:0010976  positive regulation of neuron projection development
GO:0010881  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027  regulation of heart rate
GO:0010880  regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060314  regulation of ryanodine-sensitive calcium-release channel activity
GO:0014819  regulation of skeletal muscle contraction
GO:0014809  regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0006355  regulation of transcription, DNA-dependent

Cellular Component

GO:0015629  actin cytoskeleton
GO:0009986  cell surface
GO:0030055  cell-substrate junction
GO:0043034  costamere
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0016010  dystrophin-associated glycoprotein complex
GO:0030175  filopodium
GO:0016328  lateral plasma membrane
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0043234  protein complex
GO:0042383  sarcolemma
GO:0016013  syntrophin complex
GO:0030018  Z disc

Molecular Function

GO:0003779  actin binding
GO:0005509  calcium ion binding
GO:0017022  myosin binding
GO:0050998  nitric-oxide synthase binding
GO:0005515  protein binding
GO:0005200  structural constituent of cytoskeleton
GO:0008307  structural constituent of muscle
GO:0017166  vinculin binding
GO:0008270  zinc ion binding