angiotensin II receptor, type 2

詳細情報を見る

同義遺伝子名

MRX88, angiotensin II receptor, type 2, Type-2 angiotensin II receptor, AT2, AGTR2, angiotensin receptor 2, ATGR2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.52 小脳:3.60 脳幹:3.57 脳梁:3.57 松果体:- 末梢神経:3.61 脊柱:3.69 網膜:- 目:- 動脈:3.61 静脈:3.59 リンパ節:3.56 末梢血:- 脾臓:3.43 胸腺:3.47 骨髄:3.73 脂肪:3.64 骨:- 皮膚:3.52
CAGE 大脳:0.06 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:0 リンパ節:0.20 末梢血:- 脾臓:0 胸腺:0.18 骨髄:- 脂肪:0.14 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.11 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:9.10 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:51.10 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:14.70    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.78 胎盤:3.53 前立腺:3.43 卵巣:3.42 精巣:3.51 心臓:3.48 骨格筋:3.70 食道:3.48 胃:3.43 腸:3.42 結腸:3.64 肝臓:3.64 肺:3.39 膀胱:- 腎臓:3.53 下垂体:3.52 甲状腺:3.53 副腎:3.59 膵臓:3.59 乳腺:3.40 唾液腺:3.40
CAGE 子宮:1.79 胎盤:0 前立腺:0 卵巣:0.52 精巣:0.07 心臓:0.27 骨格筋:0 食道:0.09 胃:- 腸:0 結腸:0     肝臓:0    肺:2.77 膀胱:0 腎臓:0.15 下垂体:0 甲状腺:0 副腎:- 膵臓:0.58 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.15 卵巣:0.36 精巣:0.20 心臓:0.16 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.12     肝臓:0        肺:1.49    膀胱:- 腎臓:0.05 下垂体:- 甲状腺:0.03 副腎:0.06 膵臓:- 乳腺:0 唾液腺:-

IDs

Refseq ID NM_000686
Gene ID 186
Unigene ID Hs.405348
Probe set ID 207293_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000180772
GTEx ID ENSG00000180772

オーソログ対応遺伝子

マウス[1]  NM_007429
ラット[1]  NM_007429

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007610  behavior
GO:0001974  blood vessel remodeling
GO:0007420  brain development
GO:0002035  brain renin-angiotensin system
GO:0007166  cell surface receptor linked signal transduction
GO:0006883  cellular sodium ion homeostasis
GO:0021695  cerebellar cortex development
GO:0042416  dopamine biosynthetic process
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007199  G-protein signaling, coupled to cGMP nucleotide second messenger
GO:0006954  inflammatory response
GO:0043537  negative regulation of blood vessel endothelial cell migration
GO:0030308  negative regulation of cell growth
GO:0048147  negative regulation of fibroblast proliferation
GO:0010459  negative regulation of heart rate
GO:0051387  negative regulation of nerve growth factor receptor signaling pathway
GO:0010700  negative regulation of norepinephrine secretion
GO:0007263  nitric oxide mediated signal transduction
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0050715  positive regulation of cytokine secretion
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0051000  positive regulation of nitric-oxide synthase activity
GO:0032516  positive regulation of phosphoprotein phosphatase activity
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045909  positive regulation of vasodilation
GO:0007243  protein kinase cascade
GO:0008217  regulation of blood pressure
GO:0001991  regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0042990  regulation of transcription factor import into nucleus
GO:0002018  renin-angiotensin regulation of aldosterone production
GO:0010243  response to organic nitrogen
GO:0002033  vasodilation by angiotensin involved in regulation of systemic arterial blood pressure

Cellular Component

GO:0005576  extracellular region
GO:0005887  integral to plasma membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0004945  angiotensin type II receptor activity
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0048019  receptor antagonist activity
GO:0008134  transcription factor binding