v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

詳細情報を見る

同義遺伝子名

c-erbB-3, c-erbB3, p85-sErbB3, p45-sErbB3, ERBB3, ErbB-3, MGC88033, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3 precursor, p180-ErbB3, HER3, MDA-BF-1, erbB3-S

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:150.50 小脳:37.80 脳幹:- 脳梁:145.80 松果体:- 末梢神経:460.10 脊柱:336.90 網膜:- 目:35.30 動脈:30 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:48
GeneChip nodata
CAGE 大脳:3.13 小脳:- 脳幹:3.87 脳梁:4.61 松果体:2.03 末梢神経:- 脊柱:3.37 網膜:- 目:- 動脈:2.34 静脈:1.76 リンパ節:1.54 末梢血:- 脾臓:0 胸腺:0.42 骨髄:- 脂肪:0.55 骨:- 皮膚:-
RNA-seq 大脳:0.57 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.51 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.12 骨:- 皮膚:-
EST 子宮:45.60 胎盤:72.90 前立腺:157.70 卵巣:37.30 精巣:4.30 心臓:102.20 骨格筋:20.10 食道:342.80 胃:42.50 腸:64.80 結腸:195     肝臓:10.60        肺:215.10    膀胱:- 腎臓:114.40 下垂体:- 甲状腺:- 副腎:50.80 膵臓:35.60 乳腺:176.60 唾液腺:-
GeneChip nodata
CAGE 子宮:2.31 胎盤:3.58 前立腺:3.27 卵巣:1.41 精巣:1.22 心臓:1.65 骨格筋:0.86 食道:3.64 胃:- 腸:4.59 結腸:4.50     肝臓:3.83    肺:3.37 膀胱:2.51 腎臓:3.23 下垂体:0.66 甲状腺:2.50 副腎:- 膵臓:3.84 乳腺:2.74 唾液腺:4.64
RNA-seq 子宮:- 胎盤:- 前立腺:0.62 卵巣:0.06 精巣:0.19 心臓:0.11 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.76     肝臓:1.16        肺:1.37    膀胱:- 腎臓:0.93 下垂体:- 甲状腺:0.24 副腎:0.00 膵臓:- 乳腺:0.17 唾液腺:-

IDs

Refseq ID NM_001005915
Gene ID 2065
Unigene ID Hs.118681
Probe set ID -
Ensembl ID ENSG00000065361
GTEx ID ENSG00000065361

オーソログ対応遺伝子

マウス[2]  NM_010153
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

2164210
2687875
7514177
7538656
7556068
7592681
7656248
7685162
7689552
7847801
8188716
8669836
8702572
8889548
9130710
9168114
9168115
9516479
9565587
9681822
9694850
9756944
10095121
10369675
10383151
10527633
10559227
10572067
10682683
10710290
10799311
11114724
11166154
11173924
11189010
11278868
11325528
11326315
11337467
11389077
11546794
11555649
11807823
11821958
11859873
11867753
11914075
12093292
12154198
12411582
12477932
12483526
12556529
12618754
12646923
12768307
12789268
12824184
12840049
12853564
12888923
12939402
14576349
14614020
14647450
14702039
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15141384
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15282549
15358134
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15489334
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15520002
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15704104
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17210635
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19609946
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23999432
24014028
24036211
24084886
24097984
24300455
24346286
24519943
24662824

遺伝子オントロジー  (GO ID)

Biological Process

GO:0021545  cranial nerve development
GO:0003197  endocardial cushion development
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007507  heart development
GO:0045087  innate immune response
GO:0007162  negative regulation of cell adhesion
GO:0043524  negative regulation of neuron apoptosis
GO:0051048  negative regulation of secretion
GO:0009968  negative regulation of signal transduction
GO:0048011  nerve growth factor receptor signaling pathway
GO:0051402  neuron apoptosis
GO:0007422  peripheral nervous system development
GO:0014065  phosphoinositide 3-kinase cascade
GO:0048015  phosphoinositide-mediated signaling
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0042127  regulation of cell proliferation
GO:0014037  Schwann cell differentiation
GO:0007165  signal transduction
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0042060  wound healing

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005615  extracellular space
GO:0005887  integral to plasma membrane
GO:0016328  lateral plasma membrane
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0019838  growth factor binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0030296  protein tyrosine kinase activator activity
GO:0004713  protein tyrosine kinase activity
GO:0004888  transmembrane receptor activity