coagulation factor II (thrombin) receptor

同義遺伝子名

coagulation factor II (thrombin) receptor, Thrombin receptor, protease-activated receptor 1 (PAR-1), Proteinase-activated receptor 1 precursor, Coagulation factor II receptor, HTR, CF2R, PAR-1, protease-activated receptor 1 (PAR1), F2R

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:2.77

小脳:2.74

脳幹:2.68

脳梁:2.93

松果体:-

末梢神経:3.03

脊柱:2.99

網膜:-

目:-

動脈:4.35

静脈:3.80

リンパ節:3.89

末梢血:-

脾臓:7.05

胸腺:3.05

骨髄:3.07

脂肪:3.24

骨:-

皮膚:4.72

CAGE

大脳:1.18

小脳:-

脳幹:0.83

脳梁:2.11

松果体:2.46

末梢神経:-

脊柱:2.05

網膜:-

目:-

動脈:4.25

静脈:2.95

リンパ節:3.20

末梢血:-

脾臓:4.91

胸腺:2.11

骨髄:-

脂肪:3.06

骨:-

皮膚:-

RNA-seq

大脳:0.76

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.76

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.35

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:4.99

胎盤:3.36

前立腺:3.35

卵巣:3.64

精巣:4.27

心臓:4.40

骨格筋:2.73

食道:3.63

胃:4.29

腸:4.16

結腸:3.38

肝臓:4.52

肺:5.69

膀胱:-

腎臓:4.07

下垂体:3.14

甲状腺:3.87

副腎:5.94

膵臓:2.84

乳腺:5.25

唾液腺:3.32

CAGE

子宮:3.51

胎盤:4.13

前立腺:3.08

卵巣:2.62

精巣:3.69

心臓:3.86

骨格筋:2.35

食道:3.00

胃:-

腸:3.47

結腸:3.21

肝臓:3.70

肺:3.90

膀胱:3.12

腎臓:3.69

下垂体:2.19

甲状腺:2.92

副腎:-

膵臓:1.74

乳腺:2.95

唾液腺:2.57

RNA-seq

子宮:-

胎盤:-

前立腺:2.42

卵巣:2.30

精巣:2.72

心臓:3.05

骨格筋:1.47

食道:-

胃:-

腸:-

結腸:2.92

肝臓:2.77

肺:4.16

膀胱:-

腎臓:3.61

下垂体:-

甲状腺:2.39

副腎:2.87

膵臓:-

乳腺:2.39

唾液腺:-

IDs

Refseq ID	NM_001992
Gene ID	2149
Unigene ID	-
Probe set ID	203989_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000181104
GTEx ID	ENSG00000181104

オーソログ対応遺伝子

マウス[2]	NM_010169
ラット [0]

染色体

5q13.3 [76,011,868 - 76,031,606]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR002286	P2 purinoceptor
IPR003912	Protease-activated receptor
IPR000935	Thrombin receptor

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0000186	activation of MAPKK activity
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0009653	anatomical structure morphogenesis
GO:0007596	blood coagulation
GO:0002248	connective tissue replacement during inflammatory response
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007529	establishment of synaptic specificity at neuromuscular junction
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0048873	homeostasis of number of cells within a tissue
GO:0006954	inflammatory response
GO:0008285	negative regulation of cell proliferation
GO:0003105	negative regulation of glomerular filtration
GO:0043524	negative regulation of neuron apoptosis
GO:0030168	platelet activation
GO:0060155	platelet dense granule organization
GO:0030194	positive regulation of blood coagulation
GO:0051928	positive regulation of calcium ion transport
GO:0043280	positive regulation of caspase activity
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0032967	positive regulation of collagen biosynthetic process
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046427	positive regulation of JAK-STAT cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
GO:0035025	positive regulation of Rho protein signal transduction
GO:0045987	positive regulation of smooth muscle contraction
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0045907	positive regulation of vasoconstriction
GO:0030193	regulation of blood coagulation
GO:0032651	regulation of interleukin-1 beta production
GO:0051930	regulation of sensory perception of pain
GO:0051209	release of sequestered calcium ion into cytosol
GO:0032496	response to lipopolysaccharide
GO:0009611	response to wounding
GO:0007262	STAT protein nuclear translocation
GO:0007260	tyrosine phosphorylation of STAT protein

Cellular Component

GO:0005901	caveola
GO:0005576	extracellular region
GO:0005794	Golgi apparatus
GO:0005887	integral to plasma membrane
GO:0031594	neuromuscular junction
GO:0005886	plasma membrane
GO:0031094	platelet dense tubular network
GO:0045211	postsynaptic membrane

Molecular Function

GO:0001965	G-protein alpha-subunit binding
GO:0031681	G-protein beta-subunit binding
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0005102	receptor binding
GO:0015057	thrombin receptor activity

coagulation factor II (thrombin) receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function