fibroblast growth factor 2 (basic)

詳細情報を見る

同義遺伝子名

HBGH-2, fibroblast growth factor 2 (basic), Heparin-binding growth factor 2 precursor, Prostatropin, BFGF, Basic fibroblast growth factor, HBGF-2, FGFB, FGF2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.10 小脳:- 脳幹:- 脳梁:87.50 松果体:- 末梢神経:92 脊柱:- 網膜:- 目:41.10 動脈:30 静脈:- リンパ節:30.30 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:40.30 骨:38.40 皮膚:144
GeneChip 大脳:4.37 小脳:4.15 脳幹:4.48 脳梁:4.40 松果体:- 末梢神経:4.54 脊柱:4.64 網膜:- 目:- 動脈:5.05 静脈:4.88 リンパ節:3.85 末梢血:- 脾臓:3.82 胸腺:3.83 骨髄:4.14 脂肪:4.99 骨:- 皮膚:4.35
CAGE 大脳:0.65 小脳:- 脳幹:0.85 脳梁:0.70 松果体:0.62 末梢神経:- 脊柱:1.09 網膜:- 目:- 動脈:0.87 静脈:0 リンパ節:0.23 末梢血:- 脾臓:0.17 胸腺:0.06 骨髄:- 脂肪:1.12 骨:- 皮膚:-
RNA-seq 大脳:3.76 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.28 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.31 骨:- 皮膚:-
EST 子宮:665.30 胎盤:3.60 前立腺:- 卵巣:149.10 精巣:13 心臓:25.50 骨格筋:- 食道:- 胃:637.30 腸:64.80 結腸:-     肝臓:-        肺:24.40    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:35.60 乳腺:55.80 唾液腺:-
GeneChip 子宮:4.73 胎盤:4.29 前立腺:4.25 卵巣:4.77 精巣:3.85 心臓:4.52 骨格筋:4.35 食道:4.07 胃:4.31 腸:4.09 結腸:4.14 肝臓:3.80 肺:4.19 膀胱:- 腎臓:4.24 下垂体:4.02 甲状腺:3.90 副腎:3.97 膵臓:4.18 乳腺:4.25 唾液腺:4.14
CAGE 子宮:1.35 胎盤:0.16 前立腺:1.11 卵巣:1.43 精巣:0.53 心臓:0.63 骨格筋:0.09 食道:0.63 胃:- 腸:0.21 結腸:0.51     肝臓:0    肺:0.48 膀胱:1.24 腎臓:0.27 下垂体:0.10 甲状腺:0.57 副腎:- 膵臓:0 乳腺:0.90 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:3.66 卵巣:3.44 精巣:2.19 心臓:1.47 骨格筋:1.12 食道:- 胃:- 腸:- 結腸:3.75     肝臓:0.56        肺:4.13    膀胱:- 腎臓:2.13 下垂体:- 甲状腺:1.59 副腎:2.35 膵臓:- 乳腺:4.32 唾液腺:-

IDs

Refseq ID NM_002006
Gene ID 2247
Unigene ID Hs.284244
Probe set ID 204421_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138685
GTEx ID ENSG00000138685

オーソログ対応遺伝子

マウス[1]  NM_008006
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1417798
1697263
1702556
1707542
1769963
1785797
1849658
1885605
2265560
2320377
2435284
2435575
2538817
2726761
3472745
3579930
3732516
3780670
3964259
7532176
7691311
7735329
7935812
7999082
8344959
8530375
8622701
8663044
8885834
9139660
9266968
9342064
9553078
9558385
9576942
9712850
9826564
9858574
9925931
10358027
10397733
10438928
10490103
10574949
10579907
10652299
10830168
10848592
10903182
10950949
11030354
11053263
11066092
11075807
11141237
11276432
11294897
11390973
11418238
11509569
11598182
11708770
11716516
11742492
11796824
11815602
11847221
11864711
11891198
11891801
11928807
11940567
11960370
11964307
11976347
11985797
11986954
11999550
12000311
12006402
12008951
12020352
12032827
12054499
12057924
12080186
12087465
12145206
12168799
12172783
12209593
12235165
12369790
12393937
12403780
12428103
12477932
12478660
12496364
12509902
12517814
12538477
12545206
12571252
12574959
12590983
12607599
12623787
12631064
12631070
12651930
12659634
12660731
12676798
12682649
12717444
12727994
12746216
12755687
12799459
12815619
12823444
12857600
12857733
12871330
12871334
12872165
13680247
14523006
14630795
14669345
14672345
14680499
14699503
14706681
15033176
15096041
15117822
15120936
15146197
15166228
15199049
15208265
15243127
15247002
15247275
15249224
15293454
15297314
15302993
15316024
15342556
15464234
15481452
15496150
15525641
15573376
15603823
15610530
15631865
15680705
15689238
15695515
15703886
15713745
15725477
15726914
15731686
15737206
15756443
15769511
15769981
15780951
15809086
15817123
15825079
15875316
15875782
15879597
15906377
15924676
15942693
15947088
15985216
15996482
16020751
16077964
16077988
16080018
16095497
16103882
16135988
16160009
16210019
16222707
16227592
16257968
16278388
16304044
16320338
16436505
16463783
16490198
16495214
16521228
16597610
16597617
16631837
16638370
16685268
16709186
16723715
16739027
16769728
16807244
16816927
16820871
16822883
16840552
16867222
16876430
16905765
16949906
16982797
16996573
17133345
17157157
17166351
17167778
17169545
17204151
17217840
17234579
17285972
17298206
17381064
17466952
17478553
17487982
17497037
17500071
17503459
17505261
17522998
17532297
17537644
17537668
17543283
17556598
17562265
17578349
17605857
17637743
17651425
17653045
17676480
17699594
17706726
17724016
17726742
17762899
17825301
17929017
17942638
17949478
17968311
17968943
17981115
17996481
17997184
18006148
18025790
18031768
18036796
18042549
18051571
18052595
18055262
18059339
18088275
18093228
18094712
18164591
18164704
18171671
18179408
18187129
18253936
18258238
18279437
18281281
18298475
18329368
18332228
18347025
18364383
18419755
18420995
18438927
18452581
18476630
18481005
18511454
18519946
18549879
18555217
18570917
18592007
18635606
18639416
18680389
18698254
18705695
18773427
18783914
18802039
18803285
18819464
18829480
18930044
18974971
18979395
19056764
19059221
19061884
19086919
19096229
19096867
19100714
19107653
19147956
19160106
19196427
19197140
19217457
19235591
19245795
19279131
19287993
19301256
19308772
19318994
19319189
19351956
19386985
19423540
19453261
19456219
19477940
19478386
19489096
19495899
19533745
19541589
19556344
19577615
19586755
19587357
19608737
19614919
19617559
19631775
19631914
19651147
19670348
19696444
19710942
19713533
19781633
19802384
19822079
19828453
19885553
19890880
19892399
19913121
19919531
19930868
19933269
19950605
19952401
20001221
20016498
20053757
20056600
20116383
20122687
20127022
20128380
20150555
20197313
20202860
20206949
20224347
20230531
20335309
20339243
20362567
20363749
20371606
20406964
20438785
20452482
20504760
20504870
20514456
20526813
20571834
20628086
20628269
20628624
20634891
20641033
20644561
20645833
20646480
20672350
20673868
20681019
20713592
20817637
20819778
20850693
20857427
20886037
20926602
20945415
21029699
21037114
21041608
21041986
21048031
21139048
21161264
21209880
21224050
21266348
21350328
21381082
21382096
21460777
21471211
21501244
21506108
21506113
21515689
21528671
21539890
21572099
21678127
21695795
21699503
21720547
21733164
21761458
21766497
21771176
21830216
21832283
21835001
21855631
21894939
21919032
21923031
21942441
21996542
21997191
21998584
22009965
22016523
22102278
22125837
22158871
22174424
22193058
22228819
22233184
22237711
22260074
22267482
22335910
22393273
22493287
22506349
22508498
22542539
22546563
22577248
22599586
22680042
22730382
22732006
22804708
22836867
22895562
22927437
22932066
22962037
22967508
23053181
23071632
23086340
23122986
23154434
23236888
23239497
23243019
23264596
23265436
23290762
23301033
23322705
23331079
23335070
23352645
23385422
23435034
23448571
23457216
23463326
23485603
23536707
23604117
23620752
23630597
23677479
23800732
23861152
23869761
23872928
23891065
23951165
23970062
23990967
23991123
23998120
24014875
24021953
24063890
24066673
24089521
24122792
24188024
24216509
24329908
24398102
24481949

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0000186  activation of MAPKK activity
GO:0060128  adrenocorticotropin hormone secreting cell differentiation
GO:0006915  apoptosis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0006700  C21-steroid hormone biosynthetic process
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0006935  chemotaxis
GO:0060591  chondroblast differentiation
GO:0048598  embryonic morphogenesis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0030198  extracellular matrix organization
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0010001  glial cell differentiation
GO:0030214  hyaluronan catabolic process
GO:0001759  induction of an organ
GO:0045087  innate immune response
GO:0032958  inositol phosphate biosynthetic process
GO:0008286  insulin receptor signaling pathway
GO:0030324  lung development
GO:0060644  mammary gland epithelial cell differentiation
GO:0043537  negative regulation of blood vessel endothelial cell migration
GO:0060548  negative regulation of cell death
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010764  negative regulation of fibroblast migration
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007399  nervous system development
GO:0000189  nuclear translocation of MAPK
GO:0009887  organ morphogenesis
GO:0006661  phosphatidylinositol biosynthetic process
GO:0048015  phosphoinositide-mediated signaling
GO:0050918  positive chemotaxis
GO:0045766  positive regulation of angiogenesis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0051781  positive regulation of cell division
GO:0042660  positive regulation of cell fate specification
GO:0008284  positive regulation of cell proliferation
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0021940  positive regulation of granule cell precursor proliferation
GO:0045669  positive regulation of osteoblast differentiation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0010863  positive regulation of phospholipase C activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0007265  Ras protein signal transduction
GO:0045765  regulation of angiogenesis
GO:0051726  regulation of cell cycle
GO:0046668  regulation of retinal cell programmed cell death
GO:0051209  release of sequestered calcium ion into cytosol
GO:0048678  response to axon injury
GO:0007165  signal transduction
GO:0048864  stem cell development
GO:0021762  substantia nigra development
GO:0060129  thyroid stimulating hormone secreting cell differentiation
GO:0042060  wound healing

Cellular Component

GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005634  nucleus

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0017134  fibroblast growth factor binding
GO:0005104  fibroblast growth factor receptor binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0005515  protein binding