fibroblast growth factor receptor 1

同義遺伝子名

CEK, bFGF-R, N-SAM, KAL2, HBGFR, Fms-like tyrosine kinase 2, CD331, FLT2, FGFR1, BFGFR, FGFR-1, c-fgr, CD331 antigen, FGFBR, FLG

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:109

小脳:403

脳幹:-

脳梁:87.50

松果体:148.30

末梢神経:184

脊柱:336.90

網膜:-

目:182.20

動脈:30

静脈:266.60

リンパ節:101.10

末梢血:-

脾臓:18.90

胸腺:77.30

骨髄:137.80

脂肪:80.70

骨:268.70

皮膚:86.40

GeneChip

大脳:7.05

小脳:8.75

脳幹:7.41

脳梁:7.09

松果体:-

末梢神経:8.85

脊柱:8

網膜:-

目:-

動脈:8.82

静脈:8.82

リンパ節:7.32

末梢血:-

脾臓:6.54

胸腺:7.11

骨髄:6.65

脂肪:8.58

骨:-

皮膚:7.75

CAGE

大脳:3.75

小脳:-

脳幹:3.82

脳梁:3.55

松果体:2.85

末梢神経:-

脊柱:4.09

網膜:-

目:-

動脈:5.39

静脈:4.32

リンパ節:3.47

末梢血:-

脾臓:2.33

胸腺:3.45

骨髄:-

脂肪:4.67

骨:-

皮膚:-

RNA-seq

大脳:0.18

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.00

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:328.10

胎盤:145.70

前立腺:90.10

卵巣:372.60

精巣:134.10

心臓:63.90

骨格筋:20.10

食道:-

胃:-

腸:162

結腸:59.40

肝臓:-

肺:141.70

膀胱:-

腎臓:93.60

下垂体:116

甲状腺:-

副腎:-

膵臓:124.50

乳腺:204.40

唾液腺:-

GeneChip

子宮:8.41

胎盤:7.71

前立腺:7.59

卵巣:8.40

精巣:7.29

心臓:8.31

骨格筋:6.64

食道:7.66

胃:7.81

腸:7.63

結腸:7.96

肝臓:6.15

肺:7.89

膀胱:-

腎臓:7.13

下垂体:7.94

甲状腺:7.43

副腎:6.97

膵臓:8.31

乳腺:8.94

唾液腺:7.11

CAGE

子宮:4.65

胎盤:4.13

前立腺:4.59

卵巣:4.92

精巣:4.16

心臓:4.51

骨格筋:3.61

食道:4.31

胃:-

腸:3.18

結腸:4.17

肝臓:2.05

肺:4.01

膀胱:4.85

腎臓:3.53

下垂体:4.24

甲状腺:3.20

副腎:-

膵臓:4.67

乳腺:4.91

唾液腺:3.26

RNA-seq

子宮:-

胎盤:-

前立腺:0.00

卵巣:0.00

精巣:0.00

心臓:0.00

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.00

肝臓:0

肺:0.00

膀胱:-

腎臓:0.00

下垂体:-

甲状腺:0.00

副腎:0.00

膵臓:-

乳腺:0.00

唾液腺:-

IDs

Refseq ID	NM_023110
Gene ID	2260
Unigene ID	Hs.264887
Probe set ID	211535_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000077782
GTEx ID	ENSG00000077782

オーソログ対応遺伝子

マウス[6]	NM_001079908, NM_001079909, NM_010206
ラット [0]

染色体

8p11.22 [38,268,656 - 38,326,352]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0060117	auditory receptor cell development
GO:0007411	axon guidance
GO:0060445	branching involved in salivary gland morphogenesis
GO:0048469	cell maturation
GO:0016477	cell migration
GO:0002062	chondrocyte differentiation
GO:0043009	chordate embryonic development
GO:0030326	embryonic limb morphogenesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0001701	in utero embryonic development
GO:0001759	induction of an organ
GO:0045087	innate immune response
GO:0042472	inner ear morphogenesis
GO:0008286	insulin receptor signaling pathway
GO:0060484	lung-associated mesenchyme development
GO:0000165	MAPKKK cascade
GO:0048762	mesenchymal cell differentiation
GO:0030901	midbrain development
GO:0042474	middle ear morphogenesis
GO:0043066	negative regulation of apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0048011	nerve growth factor receptor signaling pathway
GO:0021847	neuroblast division in the ventricular zone
GO:0001764	neuron migration
GO:0042473	outer ear morphogenesis
GO:0048339	paraxial mesoderm development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0045787	positive regulation of cell cycle
GO:0008284	positive regulation of cell proliferation
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0045666	positive regulation of neuron differentiation
GO:0010976	positive regulation of neuron projection development
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0010518	positive regulation of phospholipase activity
GO:0010863	positive regulation of phospholipase C activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0045595	regulation of cell differentiation
GO:0048378	regulation of lateral mesodermal cell fate specification
GO:0007605	sensory perception of sound
GO:0001501	skeletal system development
GO:0048705	skeletal system morphogenesis
GO:0006351	transcription, DNA-dependent
GO:0001657	ureteric bud development

Cellular Component

GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004713	protein tyrosine kinase activity

fibroblast growth factor receptor 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function