fibroblast growth factor receptor 3

詳細情報を見る

同義遺伝子名

HSFGFR3EX, JTK4, CEK2, FGFR3, CD333, CD333 antigen, FGFR-3, Fibroblast growth factor receptor 3 precursor, ACH

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.80 皮膚:-
GeneChip 大脳:8.99 小脳:7.70 脳幹:8.83 脳梁:8.58 松果体:- 末梢神経:5.32 脊柱:9.27 網膜:- 目:- 動脈:5.55 静脈:4.90 リンパ節:6.65 末梢血:- 脾臓:5.74 胸腺:5.80 骨髄:5.02 脂肪:5.47 骨:- 皮膚:9.41
CAGE 大脳:3.42 小脳:- 脳幹:2.94 脳梁:3.47 松果体:0.92 末梢神経:- 脊柱:3.15 網膜:- 目:- 動脈:1.61 静脈:0.47 リンパ節:1.35 末梢血:- 脾臓:0.66 胸腺:0.68 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.13 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.03 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:4.90    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.72 胎盤:6.33 前立腺:7.24 卵巣:5.35 精巣:7.94 心臓:4.97 骨格筋:5.40 食道:9.52 胃:6.40 腸:7.25 結腸:6.56 肝臓:8.30 肺:6.68 膀胱:- 腎臓:8.74 下垂体:7.27 甲状腺:4.95 副腎:4.94 膵臓:7.81 乳腺:7.07 唾液腺:4.85
CAGE 子宮:1.19 胎盤:1.14 前立腺:1.67 卵巣:0.32 精巣:1.45 心臓:0.58 骨格筋:0 食道:3.30 胃:- 腸:2.08 結腸:2.09     肝臓:2.20    肺:1.52 膀胱:1.30 腎臓:1.50 下垂体:0.43 甲状腺:0.37 副腎:- 膵臓:2.81 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:2.11 卵巣:0.22 精巣:0.16 心臓:0.00 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.24     肝臓:2.03        肺:0.82    膀胱:- 腎臓:0.67 下垂体:- 甲状腺:0.05 副腎:0.00 膵臓:- 乳腺:0.15 唾液腺:-

IDs

Refseq ID NM_001163213
Gene ID 2261
Unigene ID Hs.142003
Probe set ID 204379_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000068078
GTEx ID ENSG00000068078

オーソログ対応遺伝子

マウス[8]  NM_001163215, NM_001163216, NM_001163217, NM_001205270, NM_008010
ラット[1]  NM_053429, NM_001163216, NM_001163217, NM_001205270, NM_008010

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1664411
1847508
2247464
7493034
7495869
7543024
7647778
7649548
7657660
7670477
7690989
7758520
7773297
7847369
7913883
7923141
8012397
8012398
8078586
8081365
8428519
8530501
8576175
8589686
8589699
8599370
8599935
8601314
8626374
8663044
8841188
8845844
8858131
9042914
9045692
9107244
9126476
9142922
9207791
9212826
9279753
9452043
9525367
9580776
9585583
9672519
9677066
9790257
9842995
9843049
9950339
10053006
10073901
10094188
10215410
10360392
10360393
10360402
10361991
10395236
10425034
10471491
10574949
10579907
10648414
10652257
10671061
10751172
10777366
10918587
11030304
11055896
11134040
11294897
11314002
11325814
11329138
11350938
11424131
11426459
11529856
11556601
11703096
11731410
11746040
11754059
11759058
11827956
11839738
11906172
11940572
12009017
12032146
12048679
12244095
12297284
12368157
12368206
12373339
12424440
12433679
12461689
12477932
12576423
12624096
12626508
12637327
12664252
12707965
12764678
12815063
12817007
12833394
12921294
12929929
14520460
14551213
14562121
14606518
14667819
14678961
14715624
14732692
14751560
15026322
15105428
15221641
15241680
15292251
15322115
15517832
15558020
15701828
15748888
15772091
15788896
15869706
15880580
15915095
15940250
16061860
16091423
16149130
16169070
16210019
16274647
16278391
16278395
16288035
16365308
16384584
16410555
16412606
16434832
16467200
16501574
16532037
16570285
16597617
16634636
16685373
16778799
16841094
16849642
16877735
16885334
17033969
17070479
17114345
17240035
17255960
17256796
17320202
17343269
17375526
17384684
17392824
17414280
17507011
17509076
17554105
17561467
17585316
17602067
17621485
17624273
17668422
17683901
17785202
17803960
17867592
17867603
17875876
17950653
18000903
18000976
18036184
18072261
18166262
18199430
18216705
18231572
18231634
18336810
18485666
18503601
18528286
18567530
18583390
18584939
18642369
18677770
18718050
18818193
18923003
18945538
19070887
19073250
19076977
19088846
19156776
19215249
19255125
19286672
19287463
19327639
19351817
19377444
19381019
19404844
19407216
19449410
19449430
19453261
19551630
19594619
19621447
19694823
19722178
19728793
19729838
19752524
19761767
19812598
19821490
19837276
19838370
19843069
19843843
19845664
19855393
19863427
19888223
19898608
19901323
19909015
20197130
20234367
20301331
20301540
20301588
20301628
20301650
20348956
20393505
20404005
20420824
20538960
20539070
20542753
20634891
20643727
20646825
20665023
20673820
20711586
20713021
20717167
20824703
20890030
20972438
21048031
21072204
21116113
21116115
21119106
21152424
21225389
21264819
21273290
21273588
21324899
21356388
21383697
21388956
21403567
21451043
21459758
21487019
21521775
21536014
21547910
21577207
21683397
21779335
21792889
21815251
21894939
22038757
22045636
22099989
22145492
22161110
22188534
22203473
22285006
22329352
22375084
22401680
22401682
22417847
22422578
22448597
22529939
22730329
22777346
22837387
22869148
22903874
22939624
23019225
23044018
23113306
23142690
23165795
23175443
23232572
23272046
23287481
23298836
23325524
23352301
23393200
23397188
23409016
23437153
23448340
23468956
23649205
23650517
23661334
23664540
23696738
23726269
23727984
23744832
23778527
23786770
23823235
23842048
23902722
23972473
23991606
24038754
24075385
24120763
24163127
24295726
24329908
24722188

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060385  axonogenesis involved in innervation
GO:0070977  bone maturation
GO:0060349  bone morphogenesis
GO:0002062  chondrocyte differentiation
GO:0090102  cochlea development
GO:0048546  digestive tract morphogenesis
GO:0003416  endochondral bone growth
GO:0001958  endochondral ossification
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0045087  innate immune response
GO:0060113  inner ear receptor cell differentiation
GO:0008286  insulin receptor signaling pathway
GO:0007259  JAK-STAT cascade
GO:0070307  lens fiber cell development
GO:0002089  lens morphogenesis in camera-type eye
GO:0000165  MAPKKK cascade
GO:0002009  morphogenesis of an epithelium
GO:0022010  myelination in the central nervous system
GO:0043066  negative regulation of apoptosis
GO:0048712  negative regulation of astrocyte differentiation
GO:0048640  negative regulation of developmental growth
GO:0050680  negative regulation of epithelial cell proliferation
GO:0045839  negative regulation of mitosis
GO:0045879  negative regulation of smoothened signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048011  nerve growth factor receptor signaling pathway
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0043065  positive regulation of apoptosis
GO:0045597  positive regulation of cell differentiation
GO:0008284  positive regulation of cell proliferation
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0090080  positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0010518  positive regulation of phospholipase activity
GO:0031398  positive regulation of protein ubiquitination
GO:0042511  positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0046777  protein amino acid autophosphorylation
GO:0048678  response to axon injury
GO:0001501  skeletal system development
GO:0035019  somatic stem cell maintenance
GO:0021762  substantia nigra development

Cellular Component

GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005783  endoplasmic reticulum
GO:0005925  focal adhesion
GO:0005887  integral to plasma membrane
GO:0009898  internal side of plasma membrane
GO:0005764  lysosome
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0017134  fibroblast growth factor binding
GO:0005007  fibroblast growth factor receptor activity
GO:0005515  protein binding
GO:0004713  protein tyrosine kinase activity