FK506 binding protein 1B, 12.6 kDa

詳細情報を見る

同義遺伝子名

FKBP12.6, Rotamase 1B, Immunophilin FKBP12.6, 12.6 kDa FKBP, FKBP1B, FK506-binding protein 1B (12.6 kD), PPIase 1B, FK506-binding protein 1B, FK506 binding protein 1B, 12.6 kDa, FKBP-12.6, Peptidyl-prolyl cis-trans isomerase 1B, PKBP1L, OTK4, h-FKBP-12, FKBP1L

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:7.49 小脳:7.35 脳幹:7.26 脳梁:5.22 松果体:- 末梢神経:9.70 脊柱:6.14 網膜:- 目:- 動脈:5.85 静脈:4.96 リンパ節:4.66 末梢血:- 脾臓:4.29 胸腺:4.19 骨髄:5.57 脂肪:4.94 骨:- 皮膚:5.33
CAGE 大脳:3.47 小脳:- 脳幹:2.24 脳梁:1.70 松果体:2.11 末梢神経:- 脊柱:2.34 網膜:- 目:- 動脈:2.12 静脈:1.34 リンパ節:1.29 末梢血:- 脾臓:1.39 胸腺:1.12 骨髄:- 脂肪:1.60 骨:- 皮膚:-
RNA-seq 大脳:3.88 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.13 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.51 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.26 胎盤:5.05 前立腺:6.28 卵巣:5.08 精巣:4.54 心臓:5.12 骨格筋:4.41 食道:5.46 胃:6.36 腸:5.72 結腸:5.52 肝臓:4.51 肺:6.55 膀胱:- 腎臓:5.43 下垂体:5.17 甲状腺:6.06 副腎:4.91 膵臓:5.65 乳腺:5.25 唾液腺:5.09
CAGE 子宮:1.68 胎盤:1.55 前立腺:1.97 卵巣:1.82 精巣:1.48 心臓:1.80 骨格筋:1.15 食道:2.18 胃:- 腸:2.67 結腸:2.73     肝臓:1.95    肺:2.51 膀胱:1.89 腎臓:2.23 下垂体:1.67 甲状腺:2.48 副腎:- 膵臓:1.59 乳腺:2.74 唾液腺:1.75
RNA-seq 子宮:- 胎盤:- 前立腺:2.34 卵巣:1.87 精巣:1.72 心臓:0.06 骨格筋:0.51 食道:- 胃:- 腸:- 結腸:0.97     肝臓:1.38        肺:2.55    膀胱:- 腎臓:2.29 下垂体:- 甲状腺:2.10 副腎:1.75 膵臓:- 乳腺:1.00 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006458  'de novo' protein folding
GO:0051480  cytosolic calcium ion homeostasis
GO:0030073  insulin secretion
GO:0006936  muscle contraction
GO:0010459  negative regulation of heart rate
GO:0032513  negative regulation of protein phosphatase type 2B activity
GO:0051280  negative regulation of release of sequestered calcium ion into cytosol
GO:0060315  negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0019227  neuronal action potential propagation
GO:0018208  peptidyl-proline modification
GO:0051284  positive regulation of sequestering of calcium ion
GO:0022417  protein maturation by protein folding
GO:0000413  protein peptidyl-prolyl isomerization
GO:0042026  protein refolding
GO:0010881  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010880  regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060314  regulation of ryanodine-sensitive calcium-release channel activity
GO:0014808  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0009749  response to glucose stimulus
GO:0042542  response to hydrogen peroxide
GO:0051775  response to redox state
GO:0033197  response to vitamin E
GO:0006939  smooth muscle contraction
GO:0042098  T cell proliferation

Cellular Component

GO:0034704  calcium channel complex
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0033017  sarcoplasmic reticulum membrane
GO:0030018  Z disc

Molecular Function

GO:0019855  calcium channel inhibitor activity
GO:0030551  cyclic nucleotide binding
GO:0005528  FK506 binding
GO:0003755  peptidyl-prolyl cis-trans isomerase activity
GO:0005515  protein binding
GO:0005102  receptor binding
GO:0005219  ryanodine-sensitive calcium-release channel activity