forkhead box O1

詳細情報を見る

同義遺伝子名

forkhead box O1A (rhabdomyosarcoma), FKHR, FKH1, Forkhead box protein O1A, FOXO1A, Forkhead in rhabdomyosarcoma, FOXO1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:13 小脳:37.80 脳幹:- 脳梁:- 松果体:- 末梢神経:184 脊柱:112.30 網膜:- 目:70.50 動脈:209.80 静脈:- リンパ節:161.80 末梢血:72.90 脾臓:- 胸腺:38.70 骨髄:118.10 脂肪:121 骨:64 皮膚:100.80
GeneChip 大脳:6.68 小脳:5.63 脳幹:6.48 脳梁:7.20 松果体:- 末梢神経:8.19 脊柱:7.21 網膜:- 目:- 動脈:7.98 静脈:7.75 リンパ節:8 末梢血:- 脾臓:8.02 胸腺:7.11 骨髄:6.50 脂肪:8.46 骨:- 皮膚:7.83
CAGE 大脳:3.64 小脳:- 脳幹:3.63 脳梁:4.03 松果体:2.40 末梢神経:- 脊柱:4.18 網膜:- 目:- 動脈:4.56 静脈:4.87 リンパ節:4.65 末梢血:- 脾臓:4.22 胸腺:3.94 骨髄:- 脂肪:5.57 骨:- 皮膚:-
RNA-seq 大脳:3.19 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.69 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.76 骨:- 皮膚:-
EST 子宮:236.90 胎盤:21.90 前立腺:90.10 卵巣:149.10 精巣:43.30 心臓:38.30 骨格筋:40.20 食道:- 胃:106.20 腸:32.40 結腸:144.20     肝臓:21.10        肺:48.90    膀胱:- 腎臓:114.40 下垂体:- 甲状腺:163.70 副腎:- 膵臓:71.10 乳腺:37.20 唾液腺:-
GeneChip 子宮:8.71 胎盤:6.52 前立腺:7.25 卵巣:9.01 精巣:7.31 心臓:7.25 骨格筋:8.11 食道:7.05 胃:6.92 腸:7.14 結腸:7.13 肝臓:7.27 肺:8.04 膀胱:- 腎臓:7.18 下垂体:6.70 甲状腺:8.30 副腎:7.51 膵臓:6.34 乳腺:8.12 唾液腺:6.48
CAGE 子宮:5.05 胎盤:4.05 前立腺:4.05 卵巣:5.43 精巣:4.30 心臓:4.18 骨格筋:6.06 食道:4.15 胃:- 腸:3.91 結腸:4.45     肝臓:4.17    肺:4.78 膀胱:4.51 腎臓:3.78 下垂体:4.09 甲状腺:4.29 副腎:- 膵臓:4.34 乳腺:5.43 唾液腺:3.21
RNA-seq 子宮:- 胎盤:- 前立腺:3.71 卵巣:5.07 精巣:3.48 心臓:2.92 骨格筋:6.37 食道:- 胃:- 腸:- 結腸:3.66     肝臓:3.28        肺:3.84    膀胱:- 腎臓:3.32 下垂体:- 甲状腺:4.75 副腎:3.69 膵臓:- 乳腺:4.55 唾液腺:-

IDs

Refseq ID NM_002015
Gene ID 2308
Unigene ID Hs.370666
Probe set ID 202724_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000150907
GTEx ID ENSG00000150907

オーソログ対応遺伝子

マウス[3]  NM_019739
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7630639
7862145
8275086
8634710
8790412
9479491
10358014
10358075
10783894
10871843
10973497
11030146
11237865
11311120
11353774
11435445
11672436
11735247
11893744
11980723
12039929
12150827
12163409
12228231
12242297
12477932
12482965
12493691
12519792
12560069
12606503
12921955
12960271
12966085
13679577
14664696
14726521
15047604
15057823
15084259
15109499
15140004
15184910
15220471
15342912
15489334
15582274
15613482
15632117
15668399
15688035
15688409
15692560
15778376
15890677
15905404
15987820
16076959
16100571
16123151
16133873
16154098
16282329
16485043
16492665
16497530
16571842
16670089
16690806
16709600
16849544
16885156
16916907
16943287
16950602
16952014
16952980
16964289
16973122
16979636
17030088
17038621
17050673
17077083
17202144
17210752
17218607
17258205
17285543
17404186
17442120
17478621
17490646
17491598
17525748
17555999
17556536
17597184
17599040
17609436
17613043
17638879
17873969
17986608
17993506
18006475
18022385
18029348
18096667
18280254
18301748
18303411
18316359
18356527
18408765
18420577
18483260
18497882
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18612045
18660489
18692812
18713968
18718910
18786403
18787186
18788887
18805788
18815134
18844239
18951090
18988640
19049975
19058789
19075016
19086408
19103600
19141580
19150739
19221179
19233123
19244250
19254690
19281796
19293131
19308286
19321440
19442434
19463968
19483080
19503105
19513505
19535741
19549905
19563779
19574223
19584310
19633686
19675556
19686743
19696738
19727442
19740748
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19772960
19787258
19793722
19887561
19893043
19948975
19953635
19956688
20018872
20033803
20061393
20095040
20125105
20151947
20351326
20353756
20357092
20406953
20412774
20485516
20543840
20682687
20719862
20819778
20868688
20874444
20884733
20933505
21069157
21075101
21116854
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21179458
21185807
21238503
21298325
21320536
21321994
21373837
21388494
21396404
21423212
21440011
21440577
21442235
21505104
21510935
21539865
21541992
21613825
21655267
21666686
21670150
21696576
21697492
21708191
21747041
21775495
21804543
21993163
22013015
22072736
22089931
22159921
22180177
22197543
22213032
22266855
22315317
22343918
22374423
22389493
22400069
22411791
22417654
22454413
22489460
22515357
22538365
22552808
22569260
22622204
22653055
22675169
22761423
22761592
22821817
22865884
22931788
22992773
23002242
23025577
23029264
23035900
23041154
23059127
23077062
23105097
23142810
23160481
23255113
23263330
23277279
23291589
23381604
23389878
23401241
23435416
23460611
23469153
23494737
23532851
23574718
23603247
23614736
23615915
23640897
23677673
23686362
23721824
23733015
23733882
23748164
23778262
23799156
23803610
23814486
23855308
23865345
23874926
23951320
23995837
24140020
24145170
24268349
24334454
24374340
24423924
24448243
24478438
24746199
24762137

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001568  blood vessel development
GO:0001678  cellular glucose homeostasis
GO:0070417  cellular response to cold
GO:0034599  cellular response to oxidative stress
GO:0009267  cellular response to starvation
GO:0009790  embryonic development
GO:0031018  endocrine pancreas development
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0045444  fat cell differentiation
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0045599  negative regulation of fat cell differentiation
GO:0032873  negative regulation of stress-activated MAPK cascade
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0048513  organ development
GO:0007389  pattern specification process
GO:0048015  phosphoinositide-mediated signaling
GO:0045722  positive regulation of gluconeogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006473  protein amino acid acetylation
GO:0042127  regulation of cell proliferation
GO:0051090  regulation of transcription factor activity
GO:0006974  response to DNA damage stimulus
GO:0001659  temperature homeostasis
GO:0009888  tissue development

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0051721  protein phosphatase 2A binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0008134  transcription factor binding