filamin A, alpha

詳細情報を見る

同義遺伝子名

Alpha-filamin, OPD2, Nonmuscle filamin, Actin-binding protein 280, FMD, FLN, filamin A, Endothelial actin-binding protein, NHBP, ABP-280, filamin A, alpha (actin binding protein 280), FLNA, Filamin-A, OPD1, FLN1, ABPX, OPD, DKFZp434P031, Filamin-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:32 小脳:- 脳幹:- 脳梁:87.50 松果体:- 末梢神経:674.80 脊柱:898.40 網膜:- 目:464.30 動脈:119.90 静脈:- リンパ節:556.10 末梢血:164 脾臓:434.80 胸腺:64.40 骨髄:688.80 脂肪:484 骨:371.10 皮膚:480
GeneChip 大脳:6.16 小脳:6.15 脳幹:6.22 脳梁:6.41 松果体:- 末梢神経:8.06 脊柱:6.72 網膜:- 目:- 動脈:11.17 静脈:10.73 リンパ節:8.29 末梢血:- 脾臓:8.22 胸腺:7.11 骨髄:7.94 脂肪:8.90 骨:- 皮膚:8.44
CAGE 大脳:3.83 小脳:- 脳幹:4.04 脳梁:4.59 松果体:3.60 末梢神経:- 脊柱:4.30 網膜:- 目:- 動脈:8.37 静脈:6.34 リンパ節:5.58 末梢血:- 脾臓:5.91 胸腺:5.03 骨髄:- 脂肪:6.47 骨:- 皮膚:-
RNA-seq 大脳:2.89 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.68 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.60 骨:- 皮膚:-
EST 子宮:811.10 胎盤:251.40 前立腺:1149 卵巣:484.40 精巣:125.50 心臓:191.60 骨格筋:60.30 食道:- 胃:85 腸:291.60 結腸:1034.50     肝臓:31.70        肺:479    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:62.20 乳腺:669.10 唾液腺:-
GeneChip 子宮:10.13 胎盤:7.60 前立腺:9.90 卵巣:9.10 精巣:7.09 心臓:7.98 骨格筋:6.26 食道:8.58 胃:9.60 腸:8.83 結腸:9.61 肝臓:6.30 肺:9 膀胱:- 腎臓:7.34 下垂体:6.43 甲状腺:7.52 副腎:7.63 膵臓:6.73 乳腺:9.38 唾液腺:7.33
CAGE 子宮:7.65 胎盤:5.62 前立腺:7.61 卵巣:7.04 精巣:5.90 心臓:5.99 骨格筋:5.10 食道:7.63 胃:- 腸:6.35 結腸:7.48     肝臓:4.28    肺:6.19 膀胱:8.32 腎臓:5.50 下垂体:3.73 甲状腺:5.10 副腎:- 膵臓:4.20 乳腺:6.19 唾液腺:5.22
RNA-seq 子宮:- 胎盤:- 前立腺:6.26 卵巣:6.67 精巣:5.16 心臓:2.42 骨格筋:2.62 食道:- 胃:- 腸:- 結腸:5.85     肝臓:1.54        肺:5.37    膀胱:- 腎臓:4.50 下垂体:- 甲状腺:4.63 副腎:5.06 膵臓:- 乳腺:5.19 唾液腺:-

IDs

Refseq ID NM_001110556
Gene ID 2316
Unigene ID Hs.195464
Probe set ID 213746_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196924
GTEx ID ENSG00000196924

オーソログ対応遺伝子

マウス[1]  NM_010227
ラット[1]  NM_001134599

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

208386
1733165
1833070
2177445
2248958
2391361
3138234
3658675
4044584
6457647
7689010
8088819
8290091
8406501
8609175
8674032
8733135
8871564
9006895
9412467
9437013
9490735
9722563
9883725
10051605
10617615
10637311
10692483
11038172
11102480
11146652
11153914
11163396
11252955
11278410
11290523
11320256
11336782
11390379
11390380
11532987
11602572
11700320
11739414
11781567
11807098
11909861
11911837
11914408
11943148
12006559
12055638
12106908
12119179
12169691
12181426
12198493
12324467
12393796
12410386
12477932
12531889
12589795
12612583
12679033
12682292
12704190
12734206
12750292
12753905
12761501
12791664
12923176
14573758
14630798
14660646
14702039
14718723
14988809
15024089
15128042
15194946
15225631
15231747
15231748
15249610
15302935
15324660
15342556
15459826
15592455
15654694
15657061
15668422
15684392
15687500
15837785
15862967
15940695
15994863
16009940
16030015
16076904
16106752
16248985
16263121
16291724
16299064
16335966
16355270
16442073
16482509
16565220
16596676
16611986
16729043
16835913
16849481
16862148
16902413
16944923
16949617
16964243
17060905
17081983
17190868
17215244
17235394
17357080
17389601
17408621
17420725
17431908
17474147
17536008
17572668
17620599
17690686
17897634
17984062
18029348
18056414
18201775
18303054
18322202
18404377
18427995
18487259
18548008
18556573
18598695
18644866
18781797
18799729
18829455
19002047
19018795
19056867
19137608
19144823
19167051
19177143
19213840
19292868
19293932
19366992
19458194
19471022
19514078
19594548
19596686
19615732
19690385
19699211
19738201
19759182
19759913
19773341
19776392
19805454
19808958
19913121
19917821
19923718
19946888
20006946
20156194
20171211
20186808
20301392
20301567
20305393
20309963
20351098
20351101
20468064
20473907
20498229
20562859
20585650
20598277
20628086
20650901
20730588
20736409
20797700
20808917
20844545
20847418
20936779
20937704
21036706
21080425
21081666
21095189
21139048
21145461
21150319
21156842
21169733
21182205
21252943
21319273
21325883
21359179
21412975
21524097
21565611
21566085
21660952
21693764
21697133
21705339
21706016
21737450
21750192
21773876
21807941
21815255
21821884
21890473
21906983
21914078
21926999
21960593
21963094
21987572
22004035
22053931
22076441
22174152
22194892
22238415
22307607
22334688
22366253
22412018
22505724
22586326
22623428
22676060
22740120
22771033
22802962
22863883
22870205
22939629
22990118
23000965
23007402
23032111
23037936
23041423
23077236
23117662
23125841
23161538
23166591
23184937
23340249
23398456
23402259
23434281
23463506
23500468
23636454
23798571
23862649
23873601
24052262
24089360
24200678
24218340
24241900
24332808
24390612
24403084
24469451
24583282
24654937
24657165
24706888
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0051764  actin crosslink formation
GO:0031532  actin cytoskeleton reorganization
GO:0007596  blood coagulation
GO:0034329  cell junction assembly
GO:0042384  cilium assembly
GO:0051220  cytoplasmic sequestering of protein
GO:0045022  early endosome to late endosome transport
GO:0001837  epithelial to mesenchymal transition
GO:0045184  establishment of protein localization
GO:0007195  inhibition of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0042177  negative regulation of protein catabolic process
GO:0043433  negative regulation of transcription factor activity
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0042993  positive regulation of transcription factor import into nucleus
GO:0034394  protein localization at cell surface
GO:0050821  protein stabilization
GO:0043113  receptor clustering

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0070062  extracellular vesicular exosome
GO:0031523  Myb complex
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0005802  trans-Golgi network

Molecular Function

GO:0051015  actin filament binding
GO:0034988  Fc-gamma receptor I complex binding
GO:0001948  glycoprotein binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0005080  protein kinase C binding
GO:0048365  Rac GTPase binding
GO:0017160  Ral GTPase binding
GO:0017048  Rho GTPase binding
GO:0004871  signal transducer activity
GO:0031267  small GTPase binding
GO:0008134  transcription factor binding