glutathione peroxidase 1

詳細情報を見る

同義遺伝子名

glutathione peroxidase 1, GSHPx-1, GPx-1, GPX1, Cellular glutathione peroxidase, GSHPX1, MGC14399, Glutathione peroxidase 1, MGC88245

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:46.20 小脳:75.60 脳幹:- 脳梁:29.20 松果体:296.70 末梢神経:30.70 脊柱:224.60 網膜:- 目:199.80 動脈:359.70 静脈:799.80 リンパ節:131.40 末梢血:965.60 脾臓:132.30 胸腺:64.40 骨髄:78.70 脂肪:927.70 骨:64 皮膚:153.60
GeneChip 大脳:7.82 小脳:6.84 脳幹:8.39 脳梁:7.93 松果体:- 末梢神経:8.05 脊柱:8.39 網膜:- 目:- 動脈:8.45 静脈:8.20 リンパ節:8.98 末梢血:- 脾臓:8.31 胸腺:8.15 骨髄:9.05 脂肪:9.50 骨:- 皮膚:8.51
CAGE 大脳:2.40 小脳:- 脳幹:2.18 脳梁:1.97 松果体:2.67 末梢神経:- 脊柱:2.14 網膜:- 目:- 動脈:2.73 静脈:2.46 リンパ節:2.56 末梢血:- 脾臓:2.21 胸腺:2.65 骨髄:- 脂肪:2.45 骨:- 皮膚:-
RNA-seq 大脳:4.95 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:6.90 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:6.44 骨:- 皮膚:-
EST 子宮:136.70 胎盤:98.40 前立腺:112.60 卵巣:37.30 精巣:26 心臓:166 骨格筋:80.40 食道:- 胃:106.20 腸:64.80 結腸:93.30     肝臓:52.80        肺:117.30    膀胱:125.60 腎臓:83.20 下垂体:232 甲状腺:163.70 副腎:355.50 膵臓:124.50 乳腺:65.10 唾液腺:-
GeneChip 子宮:8.22 胎盤:7.83 前立腺:8.82 卵巣:8.39 精巣:7.75 心臓:7.96 骨格筋:8.01 食道:8.64 胃:7.89 腸:8.27 結腸:8.01 肝臓:8.89 肺:9.23 膀胱:- 腎臓:8.59 下垂体:8.14 甲状腺:8.56 副腎:9.12 膵臓:7.83 乳腺:8.52 唾液腺:7.92
CAGE 子宮:2.07 胎盤:2.36 前立腺:2.54 卵巣:2.26 精巣:2.49 心臓:2.69 骨格筋:1.85 食道:3.11 胃:- 腸:2.75 結腸:2.80     肝臓:2.84    肺:2.63 膀胱:2.61 腎臓:3.01 下垂体:2.21 甲状腺:2.72 副腎:- 膵臓:2.98 乳腺:2.59 唾液腺:2.43
RNA-seq 子宮:- 胎盤:- 前立腺:6.65 卵巣:6.16 精巣:5.90 心臓:5.01 骨格筋:5.07 食道:- 胃:- 腸:- 結腸:6.22     肝臓:7.06        肺:7.44    膀胱:- 腎臓:6.83 下垂体:- 甲状腺:6.45 副腎:6.93 膵臓:- 乳腺:8.26 唾液腺:-

IDs

Refseq ID NM_000581
Gene ID 2876
Unigene ID Hs.76686
Probe set ID 200736_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000233276
GTEx ID ENSG00000233276

オーソログ対応遺伝子

マウス[1]  NM_008160
ラット[1]  NM_008160

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

1556108
2307470
2955287
2976939
3658677
3697069
8001233
8125298
8428933
9126277
9501919
9605859
10220143
10652368
10833429
10880344
11103801
11112379
11368344
11823528
12221075
12447480
12470500
12477932
12496980
12531513
12655278
12732844
12751788
12787913
12810669
12829378
12832449
12893824
12893830
14573732
14671197
14744747
14962293
14962975
15125229
15149466
15167446
15192016
15203190
15247771
15295091
15298967
15318035
15331559
15489334
15774926
15829318
15878749
15910762
15946795
15990458
16132718
16230136
16287877
16354666
16413612
16424062
16523188
16538174
16543247
16614101
16615267
16627788
16797832
16868544
16871233
16945136
16956821
16979635
17052796
17097614
17149600
17171548
17275003
17334644
17336361
17526193
17548672
17601350
17625244
17634480
17693525
17825092
17850515
18186040
18267129
18298806
18417962
18449862
18469277
18483336
18541150
18541588
18563616
18600213
18676680
18806750
18853169
18940188
18977241
19012493
19026164
19035188
19056482
19124506
19125369
19161995
19170196
19195504
19195803
19228881
19254950
19285650
19347979
19415410
19423521
19424819
19428376
19428448
19488773
19505917
19527700
19560448
19573080
19578796
19625176
19692168
19705749
19733578
19773279
19819955
19826042
19896490
19913121
19929244
19944066
19946932
19949914
19951064
20041472
20082261
20097730
20109103
20178852
20200426
20219985
20301895
20303587
20306294
20307617
20378690
20441054
20444272
20471990
20477822
20480816
20530237
20578157
20628086
20643115
20644561
20724907
20727719
20802378
20813000
20851292
20852007
20877264
20877624
20878976
21045266
21048031
21052528
21053180
21055077
21087145
21102463
21165435
21185702
21292323
21434422
21586620
21636625
21842217
21852236
21900206
21904836
21921984
21936966
21989715
21993316
22036626
22072582
22167619
22180033
22259188
22448134
22556393
22561328
22645453
22677746
22683538
22699881
22704671
22790458
22843889
22863883
22888637
22890915
22951908
22952184
22964634
23010849
23063346
23073788
23128233
23152058
23212700
23261989
23289525
23518201
23590304
23721877
23725507
23748877
23765060
23837478
23975365
24037914
24039907
24054539
24058403
24597264

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060055  angiogenesis involved in wound healing
GO:0019369  arachidonic acid metabolic process
GO:0043534  blood vessel endothelial cell migration
GO:0045454  cell redox homeostasis
GO:0001885  endothelial cell development
GO:0045444  fat cell differentiation
GO:0006749  glutathione metabolic process
GO:0060047  heart contraction
GO:0042744  hydrogen peroxide catabolic process
GO:0006917  induction of apoptosis
GO:0008631  induction of apoptosis by oxidative stress
GO:0051702  interaction with symbiont
GO:0019372  lipoxygenase pathway
GO:0051450  myoblast proliferation
GO:0014902  myotube differentiation
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0002862  negative regulation of inflammatory response to antigenic stimulus
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0018158  protein amino acid oxidation
GO:0006144  purine base metabolic process
GO:0006195  purine nucleotide catabolic process
GO:0040029  regulation of gene expression, epigenetic
GO:0033599  regulation of mammary gland epithelial cell proliferation
GO:0043523  regulation of neuron apoptosis
GO:0010332  response to gamma radiation
GO:0042542  response to hydrogen peroxide
GO:0033194  response to hydroperoxide
GO:0010269  response to selenium ion
GO:0009609  response to symbiotic bacterium
GO:0009636  response to toxin
GO:0009410  response to xenobiotic stimulus
GO:0007605  sensory perception of sound
GO:0048741  skeletal muscle fiber development
GO:0043403  skeletal muscle tissue regeneration
GO:0001659  temperature homeostasis
GO:0006641  triglyceride metabolic process
GO:0009650  UV protection
GO:0042311  vasodilation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion

Molecular Function

GO:0004866  endopeptidase inhibitor activity
GO:0004602  glutathione peroxidase activity
GO:0017124  SH3 domain binding