glycogen synthase kinase 3 beta

詳細情報を見る

同義遺伝子名

Glycogen synthase kinase-3 beta, glycogen synthase kinase 3 beta, GSK-3 beta, GSK3B

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:21.30 小脳:12.60 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:237.30 目:58.80 動脈:- 静脈:- リンパ節:70.80 末梢血:- 脾臓:- 胸腺:51.50 骨髄:118.10 脂肪:- 骨:12.80 皮膚:67.20
GeneChip 大脳:7.10 小脳:6.71 脳幹:7.19 脳梁:6.32 松果体:- 末梢神経:7.43 脊柱:6.72 網膜:- 目:- 動脈:6.68 静脈:6.89 リンパ節:6.82 末梢血:- 脾臓:7.07 胸腺:7.22 骨髄:6.49 脂肪:6.59 骨:- 皮膚:6.81
CAGE 大脳:4.05 小脳:- 脳幹:3.85 脳梁:3.87 松果体:4.16 末梢神経:- 脊柱:3.76 網膜:- 目:- 動脈:3.44 静脈:3.69 リンパ節:3.52 末梢血:- 脾臓:4.30 胸腺:4.71 骨髄:- 脂肪:3.95 骨:- 皮膚:-
RNA-seq 大脳:1.34 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.12 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.09 骨:- 皮膚:-
EST 子宮:9.10 胎盤:51 前立腺:33.80 卵巣:37.30 精巣:47.60 心臓:25.50 骨格筋:- 食道:- 胃:446.10 腸:32.40 結腸:33.90     肝臓:63.30        肺:19.60    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:83.60 唾液腺:-
GeneChip 子宮:6.48 胎盤:7.15 前立腺:6.91 卵巣:6.62 精巣:7.95 心臓:6.97 骨格筋:6.93 食道:7.07 胃:6.58 腸:6.28 結腸:6.78 肝臓:6.69 肺:7.22 膀胱:- 腎臓:6.68 下垂体:6.49 甲状腺:6.78 副腎:7.31 膵臓:5.80 乳腺:7.15 唾液腺:6.96
CAGE 子宮:3.90 胎盤:4.18 前立腺:3.80 卵巣:3.72 精巣:3.74 心臓:3.62 骨格筋:3.49 食道:3.89 胃:- 腸:3.97 結腸:3.72     肝臓:3.68    肺:4.05 膀胱:3.77 腎臓:3.79 下垂体:3.97 甲状腺:3.62 副腎:- 膵臓:3.02 乳腺:3.58 唾液腺:3.97
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:1.28 精巣:0.85 心臓:0.09 骨格筋:0.63 食道:- 胃:- 腸:- 結腸:1.37     肝臓:0.21        肺:0.12    膀胱:- 腎臓:0.43 下垂体:- 甲状腺:0.33 副腎:0.45 膵臓:- 乳腺:0.01 唾液腺:-

IDs

Refseq ID NM_002093
Gene ID 2932
Unigene ID Hs.445733
Probe set ID 209945_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000082701
GTEx ID ENSG00000082701

オーソログ対応遺伝子

マウス[1]  NM_019827
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0016477  cell migration
GO:0007623  circadian rhythm
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0001837  epithelial to mesenchymal transition
GO:0006983  ER overload response
GO:0030010  establishment of cell polarity
GO:0045444  fat cell differentiation
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0006349  genetic imprinting
GO:0005977  glycogen metabolic process
GO:0021766  hippocampus development
GO:0044027  hypermethylation of CpG island
GO:0045087  innate immune response
GO:0007520  myoblast fusion
GO:0043066  negative regulation of apoptosis
GO:0050774  negative regulation of dendrite morphogenesis
GO:0045719  negative regulation of glycogen biosynthetic process
GO:0043407  negative regulation of MAP kinase activity
GO:0051534  negative regulation of NFAT protein import into nucleus
GO:0032091  negative regulation of protein binding
GO:0031333  negative regulation of protein complex assembly
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048011  nerve growth factor receptor signaling pathway
GO:0009887  organ morphogenesis
GO:0018105  peptidyl-serine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0001954  positive regulation of cell-matrix adhesion
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0032092  positive regulation of protein binding
GO:0045732  positive regulation of protein catabolic process
GO:0031334  positive regulation of protein complex assembly
GO:0046827  positive regulation of protein export from nucleus
GO:0032855  positive regulation of Rac GTPase activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0006611  protein export from nucleus
GO:0000320  re-entry into mitotic cell cycle
GO:0032886  regulation of microtubule-based process
GO:0048168  regulation of neuronal synaptic plasticity
GO:0042493  response to drug
GO:0010226  response to lithium ion
GO:0071109  superior temporal gyrus development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0043025  cell soma
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0043197  dendritic spine
GO:0030426  growth cone
GO:0045121  membrane raft
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0030529  ribonucleoprotein complex

Molecular Function

GO:0005524  ATP binding
GO:0008013  beta-catenin binding
GO:0005178  integrin binding
GO:0035255  ionotropic glutamate receptor binding
GO:0016301  kinase activity
GO:0051059  NF-kappaB binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0034236  protein kinase A catalytic subunit binding
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0048156  tau protein binding
GO:0050321  tau-protein kinase activity
GO:0031625  ubiquitin protein ligase binding