NCK-associated protein 1-like

 詳細情報を見る

同義遺伝子名

NCK-associated protein 1-like, hematopoietic protein 1, HEM1, Nck-associated protein 1-like, NCKAP1L, Membrane-associated protein HEM-1, Hematopoietic protein 1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:54.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:23.50 動脈:- 静脈:- リンパ節:50.60 末梢血:255.10 脾臓:283.60 胸腺:927.60 骨髄:177.10 脂肪:- 骨:435 皮膚:57.60
GeneChip 大脳:5.85 小脳:5.71 脳幹:5.96 脳梁:6.16 松果体:- 末梢神経:6.27 脊柱:6.01 網膜:- 目:- 動脈:6.23 静脈:6.43 リンパ節:7.45 末梢血:- 脾臓:7.85 胸腺:7.96 骨髄:7.87 脂肪:6.31 骨:- 皮膚:6.23
CAGE 大脳:2.86 小脳:- 脳幹:3.52 脳梁:3.72 松果体:2.65 末梢神経:- 脊柱:4.09 網膜:- 目:- 動脈:3.42 静脈:4.70 リンパ節:5.21 末梢血:- 脾臓:5.29 胸腺:5.19 骨髄:- 脂肪:4.47 骨:- 皮膚:-
RNA-seq 大脳:1.13 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.78 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.41 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:27.30 胎盤:43.70 前立腺:- 卵巣:- 精巣:13 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:-     肝臓:-        肺:53.80    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.84 胎盤:5.91 前立腺:5.83 卵巣:5.81 精巣:5.61 心臓:6.21 骨格筋:5.88 食道:6.04 胃:6.14 腸:6.33 結腸:6.27 肝臓:6.38 肺:6.89 膀胱:- 腎臓:5.78 下垂体:5.79 甲状腺:5.74 副腎:5.84 膵臓:6.19 乳腺:6.06 唾液腺:5.91
CAGE 子宮:2.61 胎盤:3.31 前立腺:2.85 卵巣:2.65 精巣:2.47 心臓:2.86 骨格筋:1.71 食道:2.92 胃:- 腸:3.21 結腸:3.20     肝臓:3.35    肺:4.43 膀胱:2.88 腎臓:2.86 下垂体:2.39 甲状腺:2.08 副腎:- 膵臓:1.98 乳腺:3.64 唾液腺:3.09
RNA-seq 子宮:- 胎盤:- 前立腺:2.71 卵巣:1.95 精巣:0.43 心臓:0.95 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:1.21     肝臓:1.15        肺:2.96    膀胱:- 腎臓:0.60 下垂体:- 甲状腺:0.99 副腎:3.66 膵臓:- 乳腺:2.16 唾液腺:-

詳細情報

IDs

Refseq ID NM_005337
Gene ID 3071
Unigene ID Hs.182014
Probe set ID 209734_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000123338
GTEx ID ENSG00000123338

オーソログ対応遺伝子

マウス[2]  NM_153505
ラット[1]  NM_001108119

染色体

12q13.13  [54,891,495  -  54,937,726]

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1932118
7643388
11337467
12477932
16055720
16344560
16417406
17696648
17875758
19946888
21890473
21906983
22505724
23000965
23022380
23251661
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0070358  actin polymerization-dependent cell motility
GO:0001782  B cell homeostasis
GO:0050853  B cell receptor signaling pathway
GO:0030866  cortical actin cytoskeleton organization
GO:0048821  erythrocyte development
GO:0030011  maintenance of cell polarity
GO:0002262  myeloid cell homeostasis
GO:0043066  negative regulation of apoptosis
GO:0032700  negative regulation of interleukin-17 production
GO:0032715  negative regulation of interleukin-6 production
GO:0030593  neutrophil chemotaxis
GO:0030838  positive regulation of actin filament polymerization
GO:0045579  positive regulation of B cell differentiation
GO:0030890  positive regulation of B cell proliferation
GO:0043372  positive regulation of CD4-positive, alpha beta T cell differentiation
GO:0043378  positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0045648  positive regulation of erythrocyte differentiation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0045621  positive regulation of lymphocyte differentiation
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0060100  positive regulation of phagocytosis, engulfment
GO:0042327  positive regulation of phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0042102  positive regulation of T cell proliferation
GO:0006461  protein complex assembly
GO:0042221  response to chemical stimulus
GO:0042493  response to drug
GO:0043029  T cell homeostasis

Cellular Component

GO:0005829  cytosol
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0031209  SCAR complex

Molecular Function

GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0030295  protein kinase activator activity
GO:0030675  Rac GTPase activator activity