high-mobility group box 1

詳細情報を見る

同義遺伝子名

High mobility group protein B1, HMG1, HMG-1, HMG3, high-mobility group box 1, High mobility group protein 1, DKFZp686A04236, HMGB1, SBP-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:11.47 小脳:11.82 脳幹:11.31 脳梁:11.78 松果体:- 末梢神経:11.53 脊柱:11.70 網膜:- 目:- 動脈:11.26 静脈:11.41 リンパ節:11.46 末梢血:- 脾臓:11.50 胸腺:12.22 骨髄:11.74 脂肪:11.48 骨:- 皮膚:11.16
CAGE 大脳:4.83 小脳:- 脳幹:4.88 脳梁:4.78 松果体:5.12 末梢神経:- 脊柱:5.16 網膜:- 目:- 動脈:4.67 静脈:4.45 リンパ節:4.46 末梢血:- 脾臓:4.59 胸腺:4.76 骨髄:- 脂肪:4.43 骨:- 皮膚:-
RNA-seq 大脳:6.18 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:6.07 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.95 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:12.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:11.78 胎盤:10.50 前立腺:11.64 卵巣:11.49 精巣:11.12 心臓:11.30 骨格筋:10.76 食道:11.25 胃:11.42 腸:11.18 結腸:11.23 肝臓:11.17 肺:11.37 膀胱:- 腎臓:11.29 下垂体:11 甲状腺:11.63 副腎:11.40 膵臓:10.84 乳腺:11.49 唾液腺:10.86
CAGE 子宮:4.62 胎盤:3.88 前立腺:4.51 卵巣:4.42 精巣:4.04 心臓:4.47 骨格筋:4.50 食道:4.63 胃:- 腸:4.29 結腸:4.42     肝臓:4.08    肺:4.64 膀胱:4.60 腎臓:4.18 下垂体:4.35 甲状腺:4.37 副腎:- 膵臓:4.06 乳腺:4.78 唾液腺:3.85
RNA-seq 子宮:- 胎盤:- 前立腺:6.29 卵巣:6.15 精巣:5.96 心臓:4.86 骨格筋:4.97 食道:- 胃:- 腸:- 結腸:6.41     肝臓:4.94        肺:6.26    膀胱:- 腎臓:5.76 下垂体:- 甲状腺:6.30 副腎:5.90 膵臓:- 乳腺:6.00 唾液腺:-

IDs

Refseq ID NM_002128
Gene ID 3146
Unigene ID Hs.596078
Probe set ID 214938_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000189403
GTEx ID ENSG00000189403

オーソログ対応遺伝子

マウス[10]  NM_010439
ラット[10]  NM_010439

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1909331
2013279
2922262
3697355
8006019
8339930
8366113
8661151
8890171
9036861
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19223331
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20193282
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24302816
24337577
24420129
24464016
24567328
24579204
24654937
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0006288  base-excision repair, DNA ligation
GO:0006921  cell structure disassembly during apoptosis
GO:0002407  dendritic cell chemotaxis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0051103  DNA ligation during DNA repair
GO:0006310  DNA recombination
GO:0006265  DNA topological change
GO:0002437  inflammatory response to antigenic stimulus
GO:0045087  innate immune response
GO:0001773  myeloid dendritic cell activation
GO:0017055  negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0031175  neuron projection development
GO:0050918  positive chemotaxis
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0043388  positive regulation of DNA binding
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0033151  V(D)J recombination

Cellular Component

GO:0009986  cell surface
GO:0000793  condensed chromosome
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0003684  damaged DNA binding
GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0005515  protein binding
GO:0050786  RAGE receptor binding
GO:0003697  single-stranded DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding