adenomatous polyposis coli

詳細情報を見る

同義遺伝子名

GS, DP3, Protein APC, DP2.5, DP2, adenomatosis polyposis coli, APC, Adenomatous polyposis coli protein, FPC

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:222.80 小脳:88.20 脳幹:- 脳梁:29.20 松果体:148.30 末梢神経:153.40 脊柱:224.60 網膜:355.90 目:41.10 動脈:60 静脈:66.60 リンパ節:70.80 末梢血:18.20 脾臓:18.90 胸腺:38.70 骨髄:39.40 脂肪:80.70 骨:25.60 皮膚:43.20
GeneChip 大脳:7.04 小脳:6.30 脳幹:7.64 脳梁:6.73 松果体:- 末梢神経:6.93 脊柱:6.99 網膜:- 目:- 動脈:4.90 静脈:4.74 リンパ節:4.54 末梢血:- 脾臓:4.68 胸腺:5.45 骨髄:4.45 脂肪:4.62 骨:- 皮膚:5.10
CAGE 大脳:4.89 小脳:- 脳幹:5.06 脳梁:4.22 松果体:4.15 末梢神経:- 脊柱:4.91 網膜:- 目:- 動脈:2.86 静脈:3.06 リンパ節:2.91 末梢血:- 脾臓:3.16 胸腺:3.16 骨髄:- 脂肪:3.30 骨:- 皮膚:-
RNA-seq 大脳:0.31 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.68 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.32 骨:- 皮膚:-
EST 子宮:82 胎盤:10.90 前立腺:- 卵巣:37.30 精巣:99.50 心臓:63.90 骨格筋:20.10 食道:- 胃:- 腸:32.40 結腸:25.40     肝臓:52.80        肺:48.90    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:65.10 唾液腺:328.40
GeneChip 子宮:5.31 胎盤:4.04 前立腺:5.54 卵巣:4.75 精巣:4.63 心臓:4.62 骨格筋:5.59 食道:4.98 胃:4.40 腸:4.79 結腸:4.14 肝臓:4.21 肺:4.71 膀胱:- 腎臓:4.08 下垂体:4.80 甲状腺:4.45 副腎:4.52 膵臓:4.13 乳腺:4.79 唾液腺:3.80
CAGE 子宮:3.26 胎盤:2.70 前立腺:3.08 卵巣:2.88 精巣:2.85 心臓:3.19 骨格筋:3.24 食道:3.09 胃:- 腸:3.53 結腸:3.00     肝臓:2.46    肺:3.05 膀胱:3.17 腎臓:2.91 下垂体:3.76 甲状腺:2.58 副腎:- 膵臓:1.42 乳腺:3.30 唾液腺:2.72
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.82 精巣:0.41 心臓:0.74 骨格筋:0.96 食道:- 胃:- 腸:- 結腸:0.12     肝臓:0.23        肺:0.26    膀胱:- 腎臓:0.04 下垂体:- 甲状腺:0.56 副腎:0.39 膵臓:- 乳腺:0.40 唾液腺:-

IDs

Refseq ID NM_001127511
Gene ID 324
Unigene ID Hs.158932
Probe set ID 203525_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134982
GTEx ID ENSG00000134982

オーソログ対応遺伝子

マウス[3]  NM_007462
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0006915  apoptosis
GO:0009798  axis specification
GO:0007409  axonogenesis
GO:0007155  cell adhesion
GO:0007050  cell cycle arrest
GO:0016477  cell migration
GO:0006921  cell structure disassembly during apoptosis
GO:0051276  chromosome organization
GO:0000281  cytokinesis after mitosis
GO:0031122  cytoplasmic microtubule organization
GO:0009953  dorsal/ventral pattern formation
GO:0001942  hair follicle development
GO:0001822  kidney development
GO:0007094  mitotic cell cycle spindle assembly checkpoint
GO:0007091  mitotic metaphase/anaphase transition
GO:0046716  muscle homeostasis
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0060770  negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0043409  negative regulation of MAPKKK cascade
GO:0007026  negative regulation of microtubule depolymerization
GO:0042483  negative regulation of odontogenesis
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0043065  positive regulation of apoptosis
GO:0045785  positive regulation of cell adhesion
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0030858  positive regulation of epithelial cell differentiation
GO:0031116  positive regulation of microtubule polymerization
GO:0045732  positive regulation of protein catabolic process
GO:0031274  positive regulation of pseudopodium assembly
GO:0006461  protein complex assembly
GO:0009954  proximal/distal pattern formation
GO:0051988  regulation of attachment of spindle microtubules to kinetochore
GO:0032886  regulation of microtubule-based process
GO:0051171  regulation of nitrogen compound metabolic process
GO:0045667  regulation of osteoblast differentiation
GO:0045670  regulation of osteoclast differentiation
GO:0006974  response to DNA damage stimulus
GO:0060041  retina development in camera-type eye
GO:0035019  somatic stem cell maintenance
GO:0033077  T cell differentiation in the thymus
GO:0048538  thymus development
GO:0070830  tight junction assembly
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005913  cell-cell adherens junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005881  cytoplasmic microtubule
GO:0005829  cytosol
GO:0000776  kinetochore
GO:0030027  lamellipodium
GO:0016328  lateral plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0032587  ruffle membrane
GO:0005923  tight junction

Molecular Function

GO:0008013  beta-catenin binding
GO:0045296  cadherin binding
GO:0045295  gamma-catenin binding
GO:0008017  microtubule binding
GO:0051010  microtubule plus-end binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0019887  protein kinase regulator activity