apolipoprotein A-I

 詳細情報を見る

同義遺伝子名

apolipoprotein A-I, ApoA-I, MGC117399, APOA1, Apolipoprotein A-I precursor, Apo-AI

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.47 小脳:4.31 脳幹:4.51 脳梁:4.15 松果体:- 末梢神経:4.21 脊柱:4.22 網膜:- 目:- 動脈:4.89 静脈:4.60 リンパ節:4.17 末梢血:- 脾臓:4.14 胸腺:4.07 骨髄:4.53 脂肪:4.43 骨:- 皮膚:4.51
CAGE 大脳:0.15 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0.09 網膜:- 目:- 動脈:0 静脈:0.18 リンパ節:0 末梢血:- 脾臓:0.09 胸腺:0.06 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.11 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.46 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:10.60        肺:4.90    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.30 胎盤:4.09 前立腺:4.12 卵巣:4.83 精巣:8.76 心臓:4.90 骨格筋:4.58 食道:4.34 胃:4.60 腸:5.97 結腸:4.47 肝臓:12.91 肺:3.95 膀胱:- 腎臓:4.34 下垂体:4.29 甲状腺:4.20 副腎:4.51 膵臓:4.60 乳腺:4.16 唾液腺:4.47
CAGE 子宮:0.06 胎盤:0.08 前立腺:0 卵巣:1.25 精巣:3.51 心臓:1.22 骨格筋:0 食道:0 胃:- 腸:5.78 結腸:2.48     肝臓:7.33    肺:0 膀胱:0 腎臓:0 下垂体:0 甲状腺:0.06 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.29 卵巣:3.90 精巣:7.39 心臓:4.41 骨格筋:0.10 食道:- 胃:- 腸:- 結腸:0.23     肝臓:11.51        肺:0.77    膀胱:- 腎臓:0.22 下垂体:- 甲状腺:0.34 副腎:0.57 膵臓:- 乳腺:0.24 唾液腺:-

詳細情報

IDs

Refseq ID NM_000039
Gene ID 335
Unigene ID Hs.633003
Probe set ID 217073_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118137
GTEx ID ENSG00000118137

オーソログ対応遺伝子

マウス[4]  NM_009692
ラット[4]  NM_009692

染色体

11q23.3  [116,706,467  -  116,708,666]

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0014012  axon regeneration in the peripheral nervous system
GO:0007596  blood coagulation
GO:0043534  blood vessel endothelial cell migration
GO:0044255  cellular lipid metabolic process
GO:0006695  cholesterol biosynthetic process
GO:0033344  cholesterol efflux
GO:0042632  cholesterol homeostasis
GO:0070508  cholesterol import
GO:0008203  cholesterol metabolic process
GO:0030301  cholesterol transport
GO:0001935  endothelial cell proliferation
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0008211  glucocorticoid metabolic process
GO:0034380  high-density lipoprotein particle assembly
GO:0034384  high-density lipoprotein particle clearance
GO:0034375  high-density lipoprotein particle remodeling
GO:0019915  lipid storage
GO:0042158  lipoprotein biosynthetic process
GO:0042157  lipoprotein metabolic process
GO:0060354  negative regulation of cell adhesion molecule production
GO:0002740  negative regulation of cytokine secretion during immune response
GO:0034115  negative regulation of heterotypic cell-cell adhesion
GO:0050728  negative regulation of inflammatory response
GO:0050713  negative regulation of interleukin-1 beta secretion
GO:0060192  negative regulation of lipase activity
GO:0060761  negative regulation of response to cytokine stimulus
GO:0010804  negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010903  negative regulation of very-low-density lipoprotein particle remodeling
GO:0031100  organ regeneration
GO:0018206  peptidyl-methionine modification
GO:0006656  phosphatidylcholine biosynthetic process
GO:0033700  phospholipid efflux
GO:0055091  phospholipid homeostasis
GO:0007603  phototransduction, visible light
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0010873  positive regulation of cholesterol esterification
GO:0051345  positive regulation of hydrolase activity
GO:0051347  positive regulation of transferase activity
GO:0018158  protein amino acid oxidation
GO:0050821  protein stabilization
GO:0032489  regulation of Cdc42 protein signal transduction
GO:0030300  regulation of intestinal cholesterol absorption
GO:0001932  regulation of protein amino acid phosphorylation
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0007584  response to nutrient
GO:0001523  retinoid metabolic process
GO:0043691  reverse cholesterol transport
GO:0055085  transmembrane transport
GO:0070328  triglyceride homeostasis

Cellular Component

GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0005769  early endosome
GO:0030139  endocytic vesicle
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0034364  high-density lipoprotein particle
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0034774  secretory granule lumen
GO:0034366  spherical high-density lipoprotein particle
GO:0034361  very-low-density lipoprotein particle

Molecular Function

GO:0034191  apolipoprotein A-I receptor binding
GO:0034190  apolipoprotein receptor binding
GO:0001540  beta-amyloid binding
GO:0015485  cholesterol binding
GO:0017127  cholesterol transporter activity
GO:0019899  enzyme binding
GO:0008035  high-density lipoprotein binding
GO:0070653  high-density lipoprotein receptor binding
GO:0042802  identical protein binding
GO:0055102  lipase inhibitor activity
GO:0060228  phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0005543  phospholipid binding
GO:0005548  phospholipid transporter activity
GO:0005515  protein binding