insulin-like growth factor 2 (somatomedin A)

詳細情報を見る

同義遺伝子名

pp9974, FLJ44734, chromosome 11 open reading frame 43, IGF2, C11orf43, Somatomedin A, IGF-II, INSIGF, insulin-like growth factor 2 (somatomedin A), FLJ22066, Insulin-like growth factor II precursor, PP1446

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.18 小脳:5.12 脳幹:6.18 脳梁:6.57 松果体:- 末梢神経:9.45 脊柱:8.14 網膜:- 目:- 動脈:8.77 静脈:8.44 リンパ節:7 末梢血:- 脾臓:7.07 胸腺:5.33 骨髄:6.98 脂肪:9.40 骨:- 皮膚:7.16
CAGE 大脳:3.92 小脳:- 脳幹:4.75 脳梁:4.87 松果体:4.89 末梢神経:- 脊柱:6.08 網膜:- 目:- 動脈:5.94 静脈:5.87 リンパ節:4.34 末梢血:- 脾臓:4.17 胸腺:3.97 骨髄:- 脂肪:6.33 骨:- 皮膚:-
RNA-seq 大脳:0.86 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:5.36 骨:- 皮膚:-
EST 子宮:- 胎盤:18.20 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:9.12 胎盤:12.50 前立腺:6.58 卵巣:7.77 精巣:8.34 心臓:8.73 骨格筋:7.48 食道:7.85 胃:7.18 腸:6.96 結腸:7.21 肝臓:10.03 肺:6.44 膀胱:- 腎臓:7.17 下垂体:7.30 甲状腺:7.14 副腎:9.97 膵臓:6.15 乳腺:8.70 唾液腺:5.71
CAGE 子宮:6.38 胎盤:9.04 前立腺:5.95 卵巣:6.46 精巣:6.24 心臓:6.40 骨格筋:6.34 食道:5.22 胃:- 腸:3.97 結腸:4.91     肝臓:6.17    肺:4.34 膀胱:6.16 腎臓:5.00 下垂体:5.71 甲状腺:4.13 副腎:- 膵臓:5.36 乳腺:6.35 唾液腺:3.22
RNA-seq 子宮:- 胎盤:- 前立腺:3.15 卵巣:5.29 精巣:5.13 心臓:2.96 骨格筋:2.80 食道:- 胃:- 腸:- 結腸:3.67     肝臓:0.48        肺:1.43    膀胱:- 腎臓:1.62 下垂体:- 甲状腺:2.68 副腎:2.51 膵臓:- 乳腺:4.47 唾液腺:-

IDs

Refseq ID NM_000612
Gene ID 3481
Unigene ID Hs.272259
Probe set ID 202409_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000167244
GTEx ID ENSG00000167244

オーソログ対応遺伝子

マウス[6]  NM_001122736, NM_001122737, NM_010514
ラット[4]  NM_001190162, NM_001190163, NM_031511

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

658418
1282023
1486331
1569071
1656956
1684848
1714916
1730789
1733942
1845984
2450353
2465304
2722836
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3652904
3653397
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8385745
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24112161
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24380854
24407433

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0044267  cellular protein metabolic process
GO:0006349  genetic imprinting
GO:0006006  glucose metabolic process
GO:0008286  insulin receptor signaling pathway
GO:0007275  multicellular organismal development
GO:0001503  ossification
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0042104  positive regulation of activated T cell proliferation
GO:0043085  positive regulation of catalytic activity
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0046628  positive regulation of insulin receptor signaling pathway
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0006355  regulation of transcription, DNA-dependent
GO:0001501  skeletal system development

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005886  plasma membrane
GO:0031093  platelet alpha granule lumen

Molecular Function

GO:0008083  growth factor activity
GO:0005179  hormone activity
GO:0005158  insulin receptor binding
GO:0005159  insulin-like growth factor receptor binding
GO:0005515  protein binding
GO:0043539  protein serine/threonine kinase activator activity
GO:0030546  receptor activator activity