interleukin 6 receptor

詳細情報を見る

同義遺伝子名

MGC104991, IL-6R-alpha, IL6RA, IL6R, CD126 antigen, CD126, IL-6R 1, gp80, IL-6R-1, Interleukin-6 receptor alpha chain precursor, interleukin 6 receptor, Membrane glycoprotein 80

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.77 小脳:3.81 脳幹:4.89 脳梁:5.30 松果体:- 末梢神経:5.76 脊柱:5.68 網膜:- 目:- 動脈:5.87 静脈:6.08 リンパ節:7.73 末梢血:- 脾臓:7.49 胸腺:5.52 骨髄:7.56 脂肪:6.02 骨:- 皮膚:6.15
CAGE 大脳:2.04 小脳:- 脳幹:2.59 脳梁:2.43 松果体:1.73 末梢神経:- 脊柱:2.49 網膜:- 目:- 動脈:2.41 静脈:3.11 リンパ節:3.33 末梢血:- 脾臓:2.86 胸腺:2.14 骨髄:- 脂肪:2.93 骨:- 皮膚:-
RNA-seq 大脳:1.27 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.44 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.13 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.69 胎盤:4.58 前立腺:5.74 卵巣:5.99 精巣:4.71 心臓:5.60 骨格筋:5.71 食道:5.92 胃:6.40 腸:5.37 結腸:6.22 肝臓:9.58 肺:7.16 膀胱:- 腎臓:6.34 下垂体:5.76 甲状腺:4.86 副腎:6.10 膵臓:4.39 乳腺:6.28 唾液腺:4.49
CAGE 子宮:2.65 胎盤:1.84 前立腺:2.36 卵巣:2.42 精巣:2.21 心臓:2.16 骨格筋:4.59 食道:2.48 胃:- 腸:3.25 結腸:3.45     肝臓:4.19    肺:3.69 膀胱:2.58 腎臓:2.57 下垂体:2.41 甲状腺:1.65 副腎:- 膵臓:2.26 乳腺:2.69 唾液腺:1.00
RNA-seq 子宮:- 胎盤:- 前立腺:2.33 卵巣:1.53 精巣:1.25 心臓:1.07 骨格筋:5.15 食道:- 胃:- 腸:- 結腸:2.42     肝臓:3.07        肺:2.81    膀胱:- 腎臓:2.44 下垂体:- 甲状腺:2.11 副腎:2.23 膵臓:- 乳腺:1.71 唾液腺:-

IDs

Refseq ID NM_000565
Gene ID 3570
Unigene ID -
Probe set ID 205945_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000160712
GTEx ID ENSG00000160712

オーソログ対応遺伝子

マウス[2]  NM_010559
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1281789
1381187
1872801
1889804
2112585
2157217
2261637
2529343
2788034
3136546
8056053
8125298
8265649
8428753
8450224
8467812
8889549
9169421
9927325
10066782
10462375
10510402
10777583
10785334
10982829
11017875
11238858
11884403
12002769
12008038
12079407
12372336
12412787
12414855
12419823
12445803
12461182
12472176
12477932
12553038
12553555
12574959
12633863
12643274
12748171
12748876
12789531
12829785
12832423
12857602
12917504
14557255
14592826
14718574
15041717
15063602
15100312
15166129
15213442
15284182
15297310
15306846
15456942
15489334
15561970
15562008
15579373
15625895
15641051
15816827
15857508
15895091
16034137
16127269
16270750
16372246
16557588
16710414
16731080
16794539
16817825
16899024
16912152
16973585
17151125
17160948
17310346
17313958
17346257
17357077
17519976
17570254
17619842
17652155
17671508
17703412
17898129
17903307
17908769
17984249
18065760
18276608
18320358
18439548
18464913
18490707
18508242
18538149
18543249
18676680
18719127
18781131
18784373
18818748
18852330
18853133
18971377
18980999
19019335
19026125
19088723
19124510
19170196
19258923
19277666
19280716
19336475
19396608
19406470
19420002
19422646
19453261
19495883
19503017
19505916
19527514
19567438
19573080
19625176
19633828
19665805
19671870
19692168
19713205
19733878
19773279
19773451
19790045
19877065
19913121
19914334
19926672
19966016
20017315
20026129
20031577
20083667
20140262
20145925
20157327
20159251
20186139
20197062
20237496
20379614
20423763
20438838
20452482
20453000
20463041
20484876
20503287
20551110
20568250
20599261
20600579
20628086
20661738
20673868
20698883
20727736
20800603
20811626
20823887
20839491
20856253
20951753
20974296
21159831
21173340
21196890
21220034
21229891
21255427
21282511
21295508
21300955
21401300
21490132
21496483
21515913
21700295
21748280
21813064
21835044
21846873
21851175
21879314
21907864
21968316
21981268
21989726
22072558
22079540
22128229
22133618
22209080
22295972
22319020
22421339
22449275
22552503
22554704
22642608
22742541
22761857
22911828
22984080
23073775
23078005
23094986
23242610
23375120
23428306
23479153
23564454
23582566
23582716
23593036
23594084
23648090
23658720
23677452
23771909
23782174
23902164
23935104
23945879
23969696
24032723
24114630
24152848
24165468
24285489
24346288
24429361
24561123
24642471

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006953  acute-phase response
GO:0070120  ciliary neurotrophic factor-mediated signaling pathway
GO:0019221  cytokine-mediated signaling pathway
GO:0050829  defense response to Gram-negative bacterium
GO:0050830  defense response to Gram-positive bacterium
GO:0031018  endocrine pancreas development
GO:0002384  hepatic immune response
GO:0070102  interleukin-6-mediated signaling pathway
GO:0002548  monocyte chemotaxis
GO:0032966  negative regulation of collagen biosynthetic process
GO:0032717  negative regulation of interleukin-8 production
GO:0002446  neutrophil mediated immunity
GO:0010536  positive regulation of activation of Janus kinase activity
GO:0008284  positive regulation of cell proliferation
GO:0032722  positive regulation of chemokine production
GO:0032755  positive regulation of interleukin-6 production
GO:0002690  positive regulation of leukocyte chemotaxis
GO:0043410  positive regulation of MAPKKK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045669  positive regulation of osteoblast differentiation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0034097  response to cytokine stimulus

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005896  interleukin-6 receptor complex
GO:0005886  plasma membrane

Molecular Function

GO:0070119  ciliary neurotrophic factor binding
GO:0004897  ciliary neurotrophic factor receptor activity
GO:0019899  enzyme binding
GO:0019981  interleukin-6 binding
GO:0004915  interleukin-6 receptor activity
GO:0005138  interleukin-6 receptor binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity