interleukin-1 receptor-associated kinase 1

詳細情報を見る

同義遺伝子名

IRAK, interleukin-1 receptor-associated kinase 1, Interleukin-1 receptor-associated kinase 1, IRAK1, IRAK-1, pelle

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:11.90

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:30.70

脊柱:-

網膜:-

目:105.80

動脈:60

静脈:66.60

リンパ節:60.70

末梢血:54.70

脾臓:-

胸腺:12.90

骨髄:59

脂肪:121

骨:64

皮膚:28.80

GeneChip

大脳:6.62

小脳:6.21

脳幹:6.80

脳梁:6.64

松果体:-

末梢神経:6.99

脊柱:7.31

網膜:-

目:-

動脈:7.22

静脈:7.12

リンパ節:8.01

末梢血:-

脾臓:7.92

胸腺:7.20

骨髄:7.56

脂肪:7.41

骨:-

皮膚:7.73

CAGE

大脳:2.85

小脳:-

脳幹:2.93

脳梁:3.06

松果体:2.66

末梢神経:-

脊柱:3.23

網膜:-

目:-

動脈:3.10

静脈:3.42

リンパ節:4.05

末梢血:-

脾臓:4.09

胸腺:3.27

骨髄:-

脂肪:3.71

骨:-

皮膚:-

RNA-seq

大脳:1.01

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.89

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.58

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:27.30

胎盤:58.30

前立腺:135.20

卵巣:37.30

精巣:17.30

心臓:51.10

骨格筋:20.10

食道:-

胃:63.70

腸:-

結腸:84.80

肝臓:21.10

肺:29.30

膀胱:-

腎臓:52

下垂体:-

甲状腺:-

副腎:-

膵臓:17.80

乳腺:-

唾液腺:-

GeneChip

子宮:6.78

胎盤:6.69

前立腺:7.74

卵巣:7.09

精巣:6.93

心臓:6.63

骨格筋:6.50

食道:8.07

胃:7.52

腸:7.84

結腸:7.53

肝臓:7.15

肺:7.35

膀胱:-

腎臓:7.30

下垂体:6.88

甲状腺:6.92

副腎:7.84

膵臓:7.84

乳腺:7.62

唾液腺:7.99

CAGE

子宮:3.04

胎盤:3.18

前立腺:3.42

卵巣:3.35

精巣:3.28

心臓:3.33

骨格筋:3.33

食道:3.83

胃:-

腸:4.14

結腸:3.95

肝臓:4.27

肺:3.69

膀胱:3.46

腎臓:3.73

下垂体:2.46

甲状腺:3.05

副腎:-

膵臓:4.03

乳腺:4.33

唾液腺:3.64

RNA-seq

子宮:-

胎盤:-

前立腺:2.15

卵巣:2.27

精巣:1.17

心臓:0.65

骨格筋:1.49

食道:-

胃:-

腸:-

結腸:1.91

肝臓:2.46

肺:0.68

膀胱:-

腎臓:0.59

下垂体:-

甲状腺:1.63

副腎:1.83

膵臓:-

乳腺:1.70

唾液腺:-

IDs

Refseq ID	NM_001025243
Gene ID	3654
Unigene ID	Hs.522819
Probe set ID	201587_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000184216
GTEx ID	ENSG00000184216

オーソログ対応遺伝子

マウス[4]	NM_001177973, NM_001177974, NM_001177975, NM_001177976, NM_008363
ラット[1]	NM_001127555, NM_001177974, NM_001177975, NM_001177976, NM_008363

染色体

Xq28 [153,275,951 - 153,285,431]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0071456	cellular response to hypoxia
GO:0045087	innate immune response
GO:0070498	interleukin-1-mediated signaling pathway
GO:0007254	JNK cascade
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0048011	nerve growth factor receptor signaling pathway
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051259	protein oligomerization
GO:0016567	protein ubiquitination
GO:0001959	regulation of cytokine-mediated signaling pathway
GO:0070555	response to interleukin-1
GO:0032496	response to lipopolysaccharide
GO:0032494	response to peptidoglycan
GO:0007165	signal transduction
GO:0051403	stress-activated MAPK cascade
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0010008	endosome membrane
GO:0045323	interleukin-1 receptor complex
GO:0005811	lipid particle
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005149	interleukin-1 receptor binding
GO:0016301	kinase activity
GO:0004704	NF-kappaB-inducing kinase activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004842	ubiquitin-protein ligase activity

interleukin-1 receptor-associated kinase 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function