interferon regulatory factor 1

詳細情報を見る

同義遺伝子名

interferon regulatory factor 1, MAR, IRF1, IRF-1, Interferon regulatory factor 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:4.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:47 動脈:- 静脈:- リンパ節:222.40 末梢血:182.20 脾臓:170.20 胸腺:- 骨髄:59 脂肪:40.30 骨:12.80 皮膚:48
GeneChip 大脳:5.54 小脳:5.75 脳幹:5.46 脳梁:5.80 松果体:- 末梢神経:6.48 脊柱:6.58 網膜:- 目:- 動脈:7.03 静脈:7.85 リンパ節:7.47 末梢血:- 脾臓:8.39 胸腺:7.67 骨髄:7.34 脂肪:7.31 骨:- 皮膚:6.70
CAGE 大脳:2.70 小脳:- 脳幹:2.79 脳梁:2.63 松果体:2.40 末梢神経:- 脊柱:3.24 網膜:- 目:- 動脈:4.22 静脈:4.57 リンパ節:4.70 末梢血:- 脾臓:4.88 胸腺:4.52 骨髄:- 脂肪:3.90 骨:- 皮膚:-
RNA-seq 大脳:1.54 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.16 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.81 骨:- 皮膚:-
EST 子宮:72.90 胎盤:25.50 前立腺:78.90 卵巣:37.30 精巣:43.30 心臓:76.60 骨格筋:- 食道:- 胃:63.70 腸:32.40 結腸:17     肝臓:-        肺:97.80    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:71.10 乳腺:37.20 唾液腺:328.40
GeneChip 子宮:6.70 胎盤:7.89 前立腺:7.02 卵巣:6.94 精巣:6.10 心臓:6.60 骨格筋:5.87 食道:6.61 胃:7.48 腸:6.85 結腸:7.70 肝臓:6.95 肺:8.71 膀胱:- 腎臓:6.24 下垂体:6.01 甲状腺:6.88 副腎:6.37 膵臓:6.39 乳腺:6.92 唾液腺:6.11
CAGE 子宮:3.67 胎盤:4.21 前立腺:4.11 卵巣:3.56 精巣:2.70 心臓:3.78 骨格筋:3.39 食道:3.63 胃:- 腸:5.01 結腸:4.47     肝臓:3.50    肺:5.14 膀胱:3.45 腎臓:3.72 下垂体:2.76 甲状腺:4.30 副腎:- 膵臓:3.69 乳腺:4.10 唾液腺:3.49
RNA-seq 子宮:- 胎盤:- 前立腺:3.66 卵巣:2.78 精巣:2.46 心臓:1.57 骨格筋:2.34 食道:- 胃:- 腸:- 結腸:2.45     肝臓:2.15        肺:6.46    膀胱:- 腎臓:3.01 下垂体:- 甲状腺:1.64 副腎:3.80 膵臓:- 乳腺:2.51 唾液腺:-

IDs

Refseq ID NM_002198
Gene ID 3659
Unigene ID Hs.436061
Probe set ID 202531_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125347
GTEx ID ENSG00000125347

オーソログ対応遺伝子

マウス[3]  NM_001159393, NM_001159396, NM_008390
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1382447
1680796
2475256
2726461
3409321
7507207
7768900
8438156
8746784
9593745
9649509
9659924
9679752
9742224
9865486
9865487
10022868
10094406
10357819
10438822
10702232
10764778
11069564
11240951
11304541
11315919
11483597
11559933
11675348
11716756
11721695
11804954
11846971
11846972
11846974
11909852
11948194
11970993
12021315
12067985
12105194
12115600
12162881
12191570
12420205
12420214
12433281
12477932
12479817
12482935
12545159
12677441
12711307
12732645
12759449
12788988
12799427
14599866
14662860
14675396
14764039
14993214
15078941
15173018
15226432
15241475
15265939
15331704
15489234
15489334
15509808
15511228
15548708
15560761
15576464
15710386
15778351
15863386
15878912
15893730
15907481
16085646
16195385
16195814
16223733
16483648
16512786
16636311
16679314
16703666
16857162
16894313
16914093
16944293
16961714
17016442
17121613
17177148
17213842
17255955
17328074
17498560
17516545
17617740
17703412
17852336
17869652
17918184
17924060
17942705
17947510
17970693
17985330
18035482
18079498
18084608
18200030
18216101
18316378
18338947
18381204
18401423
18454680
18641303
18655181
18676680
18678606
18688264
18694960
18986693
19012493
19028144
19056926
19129219
19131452
19145247
19170196
19247692
19258923
19295429
19345417
19404407
19426920
19428110
19433065
19450680
19463200
19482358
19502235
19536153
19548631
19574175
19593445
19625176
19642896
19692168
19697121
19805480
19828629
19845895
19851330
19858727
19880820
20031576
20031577
20177805
20177960
20211142
20435892
20457620
20459687
20485362
20503287
20525893
20533260
20588308
20817723
20846942
20861350
20947504
20980339
21102463
21200019
21245151
21257209
21288140
21300955
21389130
21411754
21586271
21683060
21725055
21740303
21790247
21803131
21834067
21903422
21988832
22096509
22139419
22213332
22345458
22367195
22401175
22874466
22879909
23040881
23046934
23071666
23128233
23134341
23226549
23255602
23333304
23378427
23487038
23554911
23729439
23746807
23799084
23807161
23811275
23934855
23969696
24396068
24464131
24583282
24721577

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0043374  CD8-positive, alpha-beta T cell differentiation
GO:0007050  cell cycle arrest
GO:0071260  cellular response to mechanical stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0051607  defense response to virus
GO:0006917  induction of apoptosis
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0008285  negative regulation of cell proliferation
GO:0045590  negative regulation of regulatory T cell differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032728  positive regulation of interferon-beta production
GO:0045084  positive regulation of interleukin-12 biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032481  positive regulation of type I interferon production
GO:0002819  regulation of adaptive immune response
GO:0051726  regulation of cell cycle
GO:0045088  regulation of innate immune response
GO:0034124  regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0006366  transcription from RNA polymerase II promoter
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0000790  nuclear chromatin
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0003700  transcription factor activity