interferon regulatory factor 3

詳細情報を見る

同義遺伝子名

interferon regulatory factor 3, IRF3, IRF-3, Interferon regulatory factor 3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:42.70 小脳:12.60 脳幹:- 脳梁:- 松果体:148.30 末梢神経:61.30 脊柱:112.30 網膜:118.60 目:94 動脈:30 静脈:- リンパ節:70.80 末梢血:164 脾臓:189.10 胸腺:103.10 骨髄:- 脂肪:40.30 骨:38.40 皮膚:19.20
GeneChip 大脳:6.30 小脳:6.34 脳幹:6.34 脳梁:6.52 松果体:- 末梢神経:6.45 脊柱:6.41 網膜:- 目:- 動脈:7.03 静脈:6.55 リンパ節:8.08 末梢血:- 脾臓:8.04 胸腺:7.67 骨髄:7.04 脂肪:6.96 骨:- 皮膚:7.07
CAGE 大脳:2.27 小脳:- 脳幹:2.83 脳梁:2.85 松果体:3.67 末梢神経:- 脊柱:3.05 網膜:- 目:- 動脈:3.40 静脈:3.66 リンパ節:3.48 末梢血:- 脾臓:3.36 胸腺:3.22 骨髄:- 脂肪:2.85 骨:- 皮膚:-
RNA-seq 大脳:1.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.65 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.06 骨:- 皮膚:-
EST 子宮:54.70 胎盤:51 前立腺:67.60 卵巣:111.80 精巣:34.60 心臓:25.50 骨格筋:- 食道:- 胃:63.70 腸:- 結腸:50.90     肝臓:-        肺:44    膀胱:- 腎臓:72.80 下垂体:- 甲状腺:- 副腎:50.80 膵臓:35.60 乳腺:9.30 唾液腺:-
GeneChip 子宮:6.97 胎盤:6.59 前立腺:7.18 卵巣:7.11 精巣:6.32 心臓:6.34 骨格筋:5.82 食道:6.96 胃:7.18 腸:6.61 結腸:7.07 肝臓:6.77 肺:7.48 膀胱:- 腎臓:6.94 下垂体:7.14 甲状腺:7.47 副腎:7.23 膵臓:5.67 乳腺:7.32 唾液腺:7.03
CAGE 子宮:3.31 胎盤:3.31 前立腺:3.36 卵巣:2.99 精巣:2.39 心臓:2.87 骨格筋:2.01 食道:3.18 胃:- 腸:3.48 結腸:3.53     肝臓:2.62    肺:3.40 膀胱:3.28 腎臓:3.05 下垂体:3.40 甲状腺:3.36 副腎:- 膵臓:3.20 乳腺:2.79 唾液腺:2.90
RNA-seq 子宮:- 胎盤:- 前立腺:2.73 卵巣:3.78 精巣:2.66 心臓:1.57 骨格筋:1.46 食道:- 胃:- 腸:- 結腸:1.80     肝臓:2.17        肺:3.11    膀胱:- 腎臓:3.08 下垂体:- 甲状腺:3.28 副腎:3.44 膵臓:- 乳腺:2.68 唾液腺:-

IDs

Refseq ID NM_001571
Gene ID 3661
Unigene ID Hs.75254
Probe set ID 202621_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000126456
GTEx ID ENSG00000126456

オーソログ対応遺伝子

マウス[3]  NM_016849
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8524823
9463386
9488451
9566918
9649509
9660935
9803267
9865487
10082512
10492399
10521456
10805757
10920266
11035028
11124948
11162841
11303025
11314014
11724783
11846977
11884139
11907205
11940575
11972054
12062447
12138184
12354379
12473110
12477932
12524442
12582166
12604599
12692549
12702806
12829834
12829839
12883638
14517278
14555995
14555996
14557267
14668346
14702039
14703513
14729983
14739303
14747533
14747536
14982987
15107417
15220448
15251447
15276183
15303122
15315758
15342556
15452220
15489334
15502848
15510218
15582653
15695821
15761153
15764595
15767394
15841462
15919920
15955070
16143103
16153868
16154084
16182584
16189514
16199137
16301520
16344560
16362036
16394098
16501100
16513254
16537515
16585524
16699525
16846591
16940530
16979567
16984921
16988763
17015689
17079289
17079482
17121613
17126870
17138826
17142768
17182689
17215277
17251580
17296604
17328045
17393359
17449641
17526488
17540767
17560375
17599067
17608743
17626075
17641046
17652396
17703412
17761676
17823124
18029348
18082865
18203148
18216110
18252870
18272195
18272581
18362887
18440553
18450748
18539711
18579584
18635538
18636086
18641315
18676680
18711448
18713996
18781139
18818105
18927075
19012493
19017982
19028691
19038458
19124752
19152337
19153595
19170196
19201840
19211751
19213861
19239434
19258923
19265157
19349300
19380831
19426920
19434718
19445677
19454348
19484123
19515829
19553679
19625176
19646728
19656901
19692168
19701189
19706707
19710021
19826915
19854139
19858727
19890046
19893624
19913121
19955181
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20048147
20048166
20154210
20211142
20308324
20331378
20351107
20360684
20380698
20380700
20381110
20418377
20454685
20483755
20485298
20501320
20503287
20511230
20581830
20604809
20628086
20628368
20631144
20711230
20826620
20886096
20933442
20980500
21079688
21084468
21084487
21120614
21182093
21200386
21225257
21228327
21245146
21248248
21281747
21347389
21411754
21419663
21468605
21497908
21632562
21698224
21768204
21782231
21816816
21835786
21859832
21886773
21890473
21903422
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21931555
21935451
21940674
21988832
22027828
22028379
22072751
22079989
22114345
22127978
22158869
22170100
22208359
22294846
22307793
22388039
22394560
22394562
22479513
22588174
22593165
22647704
22705311
22709905
22745372
22843696
22906770
22908223
23027953
23028469
23077293
23122814
23154183
23281696
23303668
23478265
23512614
23532851
23542224
23552418
23596302
23649622
23650567
23755934
23824799
23846693
23929945
23951545
23994473
24036127
24049179
24250222
24257594
24275652
24275658
24335286
24385435
24622840
24726876
24763515
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0071359  cellular response to dsRNA
GO:0019221  cytokine-mediated signaling pathway
GO:0051607  defense response to virus
GO:0006917  induction of apoptosis
GO:0045087  innate immune response
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0050689  negative regulation of defense response to virus by host
GO:0045358  negative regulation of interferon-beta biosynthetic process
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0032480  negative regulation of type I interferon production
GO:0050715  positive regulation of cytokine secretion
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032727  positive regulation of interferon-alpha production
GO:0032728  positive regulation of interferon-beta production
GO:0032481  positive regulation of type I interferon production
GO:0060340  positive regulation of type I interferon-mediated signaling pathway
GO:0006974  response to DNA damage stimulus
GO:0043330  response to exogenous dsRNA
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0006366  transcription from RNA polymerase II promoter
GO:0045351  type I interferon biosynthetic process
GO:0060337  type I interferon-mediated signaling pathway
GO:0019048  virus-host interaction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0003712  transcription cofactor activity
GO:0003700  transcription factor activity