integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

詳細情報を見る

同義遺伝子名

GPIIA, ITGB1, VLAB, MDF2, FNRB, Fibronectin receptor subunit beta, CD29 antigen, Integrin beta-1 precursor, CD29, MSK12, Integrin VLA-4 subunit beta

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:2.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:8.37 小脳:6.93 脳幹:9.03 脳梁:9.13 松果体:- 末梢神経:10.22 脊柱:9.47 網膜:- 目:- 動脈:11.11 静脈:11.03 リンパ節:9.78 末梢血:- 脾臓:10.41 胸腺:9.20 骨髄:8.52 脂肪:10.96 骨:- 皮膚:9.99
CAGE 大脳:3.91 小脳:- 脳幹:4.57 脳梁:4.40 松果体:4.12 末梢神経:- 脊柱:4.99 網膜:- 目:- 動脈:6.66 静脈:5.22 リンパ節:4.81 末梢血:- 脾臓:5.64 胸腺:3.92 骨髄:- 脂肪:6.11 骨:- 皮膚:-
RNA-seq 大脳:4.99 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:6.21 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:6.98 骨:- 皮膚:-
EST 子宮:- 胎盤:3.60 前立腺:- 卵巣:37.30 精巣:- 心臓:12.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:10.98 胎盤:10.42 前立腺:10.53 卵巣:10.65 精巣:9.43 心臓:10.77 骨格筋:9.71 食道:9.54 胃:10.35 腸:10.49 結腸:9.90 肝臓:9.96 肺:10.65 膀胱:- 腎臓:9.68 下垂体:10 甲状腺:10.05 副腎:10.58 膵臓:9.76 乳腺:10.52 唾液腺:9.58
CAGE 子宮:5.82 胎盤:5.90 前立腺:5.62 卵巣:5.43 精巣:4.87 心臓:6.07 骨格筋:5.42 食道:5.65 胃:- 腸:5.29 結腸:5.36     肝臓:5.86    肺:5.79 膀胱:6.09 腎臓:5.37 下垂体:5.12 甲状腺:5.11 副腎:- 膵臓:5.10 乳腺:6.31 唾液腺:4.77
RNA-seq 子宮:- 胎盤:- 前立腺:6.90 卵巣:5.85 精巣:7.07 心臓:6.97 骨格筋:5.48 食道:- 胃:- 腸:- 結腸:3.90     肝臓:6.27        肺:7.42    膀胱:- 腎臓:5.95 下垂体:- 甲状腺:6.36 副腎:4.27 膵臓:- 乳腺:5.07 唾液腺:-

IDs

Refseq ID NM_033668
Gene ID 3688
Unigene ID Hs.643813
Probe set ID 211945_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000150093
GTEx ID ENSG00000150093

オーソログ対応遺伝子

マウス[4]  NM_010578
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0030183  B cell differentiation
GO:0007596  blood coagulation
GO:0007161  calcium-independent cell-matrix adhesion
GO:0055007  cardiac muscle cell differentiation
GO:0001708  cell fate specification
GO:0034329  cell junction assembly
GO:0016477  cell migration
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0033631  cell-cell adhesion mediated by integrin
GO:0007160  cell-matrix adhesion
GO:0006874  cellular calcium ion homeostasis
GO:0006968  cellular defense response
GO:0071479  cellular response to ionizing radiation
GO:0071260  cellular response to mechanical stimulus
GO:0071305  cellular response to vitamin D
GO:0030198  extracellular matrix organization
GO:0000082  G1/S transition of mitotic cell cycle
GO:0008354  germ cell migration
GO:0007156  homophilic cell adhesion
GO:0001701  in utero embryonic development
GO:0007229  integrin-mediated signaling pathway
GO:0007159  leukocyte adhesion
GO:0050900  leukocyte migration
GO:0060135  maternal process involved in female pregnancy
GO:0031345  negative regulation of cell projection organization
GO:0008285  negative regulation of cell proliferation
GO:0045665  negative regulation of neuron differentiation
GO:0043065  positive regulation of apoptosis
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010811  positive regulation of cell-substrate adhesion
GO:0045807  positive regulation of endocytosis
GO:0043410  positive regulation of MAPKKK cascade
GO:0045666  positive regulation of neuron differentiation
GO:0010976  positive regulation of neuron projection development
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0032594  protein transport within lipid bilayer
GO:0051726  regulation of cell cycle
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0050776  regulation of immune response
GO:0014823  response to activity
GO:0042493  response to drug
GO:0034698  response to gonadotropin stimulus
GO:0045214  sarcomere organization
GO:0070830  tight junction assembly
GO:0001894  tissue homeostasis
GO:0019048  virus-host interaction

Cellular Component

GO:0001669  acrosomal vesicle
GO:0034667  alpha3-beta1 integrin complex
GO:0034678  alpha8-beta1 integrin complex
GO:0034679  alpha9-beta1 integrin complex
GO:0005604  basement membrane
GO:0009986  cell surface
GO:0032154  cleavage furrow
GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0030175  filopodium
GO:0005925  focal adhesion
GO:0030056  hemidesmosome
GO:0008305  integrin complex
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0042470  melanosome
GO:0045121  membrane raft
GO:0031594  neuromuscular junction
GO:0005886  plasma membrane
GO:0001726  ruffle
GO:0032587  ruffle membrane
GO:0042383  sarcolemma

Molecular Function

GO:0003779  actin binding
GO:0051393  alpha-actinin binding
GO:0005518  collagen binding
GO:0001968  fibronectin binding
GO:0001948  glycoprotein binding
GO:0005178  integrin binding
GO:0043236  laminin binding
GO:0046872  metal ion binding
GO:0042277  peptide binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0046982  protein heterodimerization activity
GO:0019901  protein kinase binding
GO:0004872  receptor activity