SMAD family member 2

同義遺伝子名

hMAD-2, SMAD2, SMAD-2, MGC22139, Mad-related protein 2, JV18, SMAD 2, Mothers against decapentaplegic homolog 2, SMAD, mothers against DPP homolog 2 (Drosophila), MADH2, MGC34440, hSMAD2, MADR2, Smad-2, JV18-1, Mothers against DPP homolog 2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:6.63

小脳:6.06

脳幹:6.81

脳梁:6.78

松果体:-

末梢神経:7.06

脊柱:7.08

網膜:-

目:-

動脈:6.92

静脈:6.82

リンパ節:6.71

末梢血:-

脾臓:6.88

胸腺:7.62

骨髄:6.80

脂肪:7.30

骨:-

皮膚:7.06

CAGE

大脳:3.43

小脳:-

脳幹:3.67

脳梁:3.75

松果体:3.82

末梢神経:-

脊柱:3.67

網膜:-

目:-

動脈:3.65

静脈:3.53

リンパ節:3.62

末梢血:-

脾臓:3.84

胸腺:4.27

骨髄:-

脂肪:4.00

骨:-

皮膚:-

RNA-seq

大脳:0.32

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.84

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.46

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:7.16

胎盤:7.17

前立腺:7.32

卵巣:7.40

精巣:8.03

心臓:7.01

骨格筋:7.12

食道:6.99

胃:6.77

腸:6.91

結腸:6.83

肝臓:5.93

肺:7.18

膀胱:-

腎臓:6.70

下垂体:6.65

甲状腺:7.16

副腎:6.82

膵臓:7.24

乳腺:6.97

唾液腺:6.86

CAGE

子宮:3.79

胎盤:3.83

前立腺:3.78

卵巣:3.96

精巣:3.85

心臓:3.84

骨格筋:3.19

食道:3.84

胃:-

腸:3.62

結腸:3.57

肝臓:2.92

肺:3.85

膀胱:3.85

腎臓:3.53

下垂体:3.39

甲状腺:3.97

副腎:-

膵臓:3.57

乳腺:3.92

唾液腺:3.50

RNA-seq

子宮:-

胎盤:-

前立腺:0.65

卵巣:1.04

精巣:1.26

心臓:0.33

骨格筋:1.34

食道:-

胃:-

腸:-

結腸:0.19

肝臓:0.50

肺:1.14

膀胱:-

腎臓:0.63

下垂体:-

甲状腺:0.23

副腎:0.38

膵臓:-

乳腺:0.87

唾液腺:-

IDs

Refseq ID	NM_001003652
Gene ID	4087
Unigene ID	-
Probe set ID	203076_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000175387
GTEx ID	ENSG00000175387

オーソログ対応遺伝子

マウス[1]	NM_010754
ラット [0]

染色体

18q21.1 [45,357,922 - 45,457,515]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR003619	MAD homology 1, Dwarfin-type
IPR013019	MAD homology, MH1
IPR001132	SMAD domain, Dwarfin-type
IPR017855	SMAD domain-like
IPR008984	SMAD/FHA domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0032924	activin receptor signaling pathway
GO:0009952	anterior/posterior pattern formation
GO:0045165	cell fate commitment
GO:0007182	common-partner SMAD protein phosphorylation
GO:0048589	developmental growth
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048617	embryonic foregut morphogenesis
GO:0001706	endoderm formation
GO:0007369	gastrulation
GO:0010467	gene expression
GO:0001701	in utero embryonic development
GO:0030073	insulin secretion
GO:0030324	lung development
GO:0001707	mesoderm formation
GO:0008285	negative regulation of cell proliferation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0035265	organ growth
GO:0060021	palate development
GO:0031016	pancreas development
GO:0048340	paraxial mesoderm morphogenesis
GO:0060039	pericardium development
GO:0030513	positive regulation of BMP signaling pathway
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0031053	primary microRNA processing
GO:0051098	regulation of binding
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
GO:0070723	response to cholesterol
GO:0009749	response to glucose stimulus
GO:0007183	SMAD protein complex assembly
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0001657	ureteric bud development
GO:0007352	zygotic determination of dorsal/ventral axis

Cellular Component

GO:0032444	activin responsive factor complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0071141	SMAD protein complex
GO:0005667	transcription factor complex

Molecular Function

GO:0003682	chromatin binding
GO:0070410	co-SMAD binding
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0070411	I-SMAD binding
GO:0046872	metal ion binding
GO:0019902	phosphatase binding
GO:0005515	protein binding
GO:0070412	R-SMAD binding
GO:0046332	SMAD binding
GO:0033613	transcription activator binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0005160	transforming growth factor beta receptor binding
GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0034713	type I transforming growth factor beta receptor binding
GO:0031625	ubiquitin protein ligase binding

SMAD family member 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function