multiple endocrine neoplasia I

詳細情報を見る

同義遺伝子名

Menin, MEN1, multiple endocrine neoplasia-type I (MEN-I), multiple endocrine neoplasia-type I, multiple endocrine neoplasia I, MEAI, SCG2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:28.40 小脳:- 脳幹:6535.90 脳梁:- 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:29.40 動脈:- 静脈:66.60 リンパ節:131.40 末梢血:18.20 脾臓:- 胸腺:25.80 骨髄:- 脂肪:- 骨:- 皮膚:43.20
GeneChip 大脳:6.38 小脳:6.30 脳幹:6.27 脳梁:6.15 松果体:- 末梢神経:6.35 脊柱:6.04 網膜:- 目:- 動脈:6.15 静脈:5.71 リンパ節:6.81 末梢血:- 脾臓:6.75 胸腺:6.79 骨髄:6.30 脂肪:6.34 骨:- 皮膚:6.38
CAGE 大脳:3.02 小脳:- 脳幹:2.91 脳梁:3.04 松果体:3.21 末梢神経:- 脊柱:2.61 網膜:- 目:- 動脈:2.43 静脈:3.00 リンパ節:3.16 末梢血:- 脾臓:2.96 胸腺:3.52 骨髄:- 脂肪:2.55 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:18.20 胎盤:29.10 前立腺:33.80 卵巣:- 精巣:21.60 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:50.90     肝臓:31.70        肺:24.40    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:163.70 副腎:- 膵臓:35.60 乳腺:9.30 唾液腺:-
GeneChip 子宮:6.30 胎盤:6.59 前立腺:6.42 卵巣:6.35 精巣:6.61 心臓:5.86 骨格筋:5.56 食道:6.46 胃:6.34 腸:6.18 結腸:6.37 肝臓:6.63 肺:6.33 膀胱:- 腎臓:6.55 下垂体:6.41 甲状腺:6.72 副腎:6.49 膵臓:6.18 乳腺:6.70 唾液腺:6.55
CAGE 子宮:2.90 胎盤:2.97 前立腺:2.89 卵巣:2.91 精巣:3.18 心臓:2.36 骨格筋:1.99 食道:2.81 胃:- 腸:2.88 結腸:2.91     肝臓:3.18    肺:2.83 膀胱:2.46 腎臓:2.81 下垂体:2.81 甲状腺:3.35 副腎:- 膵臓:3.45 乳腺:2.74 唾液腺:3.08
RNA-seq 子宮:- 胎盤:- 前立腺:0 卵巣:0 精巣:0.04 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0 膵臓:- 乳腺:0 唾液腺:-

IDs

Refseq ID NM_130803
Gene ID 4221
Unigene ID Hs.423348
Probe set ID 202645_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000133895
GTEx ID ENSG00000133895

オーソログ対応遺伝子

マウス[16]  NM_001168488, NM_001168489, NM_001168490, NM_008583
ラット[1]  NM_019208, NM_001168489, NM_001168490, NM_008583

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1968641
8938448
9103196
9215689
9241276
9253601
9341881
9361035
9463336
9465067
9498491
9554741
9671267
9683585
9740255
9747036
9792884
9832038
9843042
9888389
9989505
10090472
10500243
10534569
10647896
10709111
10879731
11027505
11134142
11274402
11302744
11369988
11500056
11526476
11740047
11765049
11765051
11836268
11903322
11956591
12050235
12112656
12145286
12169273
12203793
12213668
12226747
12324758
12417605
12459032
12477932
12505253
12509449
12649288
12746426
12837246
12874027
12915685
14508515
14516745
14559791
14985373
14992727
15026366
15031321
15034196
15054094
15070966
15150273
15199122
15205994
15240620
15254225
15256779
15281352
15292357
15331604
15374998
15489334
15563473
15635078
15640349
15670192
15754732
15944766
15960975
16199523
16239140
16324211
16368411
16465412
16510874
16510875
16595707
16604156
16618927
16651450
16690369
16840830
16951149
16997566
17047380
17050672
17138574
17179192
17188139
17194968
17353931
17356705
17388795
17500065
17526943
17555499
17555500
17623761
17671196
17766243
17766710
17803708
17823710
17853334
17854391
17879353
17940620
17953629
18026121
18029348
18036394
18045958
18082152
18084346
18206547
18249304
18310293
18314630
18398822
18435740
18524795
18549467
18598942
18601604
18616711
18636154
18752793
18775714
18779856
19011561
19068082
19074834
19079338
19170121
19208834
19294466
19309299
19351817
19391077
19407509
19474519
19596783
19654304
19749796
19818711
19837273
19847644
19913121
20058152
20064463
20093773
20301710
20453000
20480190
20507346
20566584
20616437
20628086
20669561
20706287
20710116
20961854
20969866
21078971
21127195
21139048
21184284
21252315
21264250
21266030
21318185
21378168
21627674
21678021
21726266
21768215
21819486
21830623
22026581
22090276
22187299
22275377
22327296
22409234
22490989
22522645
22542456
22543820
22584706
22666734
22761894
22797925
22825745
22829075
22878668
22936661
22939629
23027861
23093699
23188049
23224434
23321498
23391111
23435440
23579270
23648481
23652667
23788249
23850066
23905891
24074368
24101467
24157940
24178797
24276465
24302194
24439903
24457600
24563463
24778252
24816145
24930734

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007420  brain development
GO:0007050  cell cycle arrest
GO:0006338  chromatin remodeling
GO:0006281  DNA repair
GO:0048704  embryonic skeletal system morphogenesis
GO:0010467  gene expression
GO:0030097  hemopoiesis
GO:0034968  histone lysine methylation
GO:0001776  leukocyte homeostasis
GO:0000165  MAPKKK cascade
GO:0060135  maternal process involved in female pregnancy
GO:0045786  negative regulation of cell cycle
GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0046329  negative regulation of JNK cascade
GO:0046621  negative regulation of organ growth
GO:0045668  negative regulation of osteoblast differentiation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0051974  negative regulation of telomerase activity
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0002076  osteoblast development
GO:0002051  osteoblast fate commitment
GO:0060021  palate development
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0051781  positive regulation of cell division
GO:0031062  positive regulation of histone methylation
GO:0045669  positive regulation of osteoblast differentiation
GO:0032092  positive regulation of protein binding
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032925  regulation of activin receptor signaling pathway
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0009411  response to UV
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0000785  chromatin
GO:0032154  cleavage furrow
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0035097  histone methyltransferase complex
GO:0016363  nuclear matrix
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0003682  chromatin binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0000400  four-way junction DNA binding
GO:0018024  histone-lysine N-methyltransferase activity
GO:0005515  protein binding
GO:0030674  protein binding, bridging
GO:0047485  protein N-terminus binding
GO:0070412  R-SMAD binding
GO:0043565  sequence-specific DNA binding
GO:0000403  Y-form DNA binding