nerve growth factor (beta polypeptide)

詳細情報を見る

同義遺伝子名

nerve growth factor, beta polypeptide, NGFB, Beta-nerve growth factor precursor, NGF, HSAN5, Beta-NGF

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:76.40 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:5.40 小脳:5.23 脳幹:5.45 脳梁:5.16 松果体:- 末梢神経:5.37 脊柱:5.01 網膜:- 目:- 動脈:5.86 静脈:6.19 リンパ節:5.13 末梢血:- 脾臓:5 胸腺:4.71 骨髄:5.17 脂肪:5.56 骨:- 皮膚:5.25
CAGE 大脳:0.60 小脳:- 脳幹:0.85 脳梁:0.34 松果体:0.91 末梢神経:- 脊柱:0.78 網膜:- 目:- 動脈:2.99 静脈:1.53 リンパ節:0.52 末梢血:- 脾臓:1.02 胸腺:0.12 骨髄:- 脂肪:0.71 骨:- 皮膚:-
RNA-seq 大脳:0.53 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.86 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.39 骨:- 皮膚:-
EST 子宮:- 胎盤:7.30 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:8.50     肝臓:-        肺:9.80    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.40 胎盤:5.16 前立腺:4.84 卵巣:5.75 精巣:4.87 心臓:5.98 骨格筋:5.62 食道:5.23 胃:5.15 腸:5.26 結腸:5.62 肝臓:5.40 肺:5.29 膀胱:- 腎臓:5.30 下垂体:4.98 甲状腺:4.95 副腎:5.38 膵臓:5.62 乳腺:5.36 唾液腺:5.46
CAGE 子宮:2.19 胎盤:0.77 前立腺:1.44 卵巣:2.48 精巣:1.30 心臓:2.33 骨格筋:0.59 食道:0.73 胃:- 腸:0.21 結腸:1.01     肝臓:1.01    肺:0.74 膀胱:1.76 腎臓:0.74 下垂体:0.90 甲状腺:1.21 副腎:- 膵臓:0 乳腺:1.92 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:1.58 卵巣:2.91 精巣:1.66 心臓:1.56 骨格筋:0.78 食道:- 胃:- 腸:- 結腸:1.58     肝臓:0.92        肺:1.05    膀胱:- 腎臓:0.85 下垂体:- 甲状腺:1.28 副腎:0.86 膵臓:- 乳腺:0.86 唾液腺:-

IDs

Refseq ID NM_002506
Gene ID 4803
Unigene ID Hs.256126
Probe set ID 206814_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134259
GTEx ID ENSG00000134259

オーソログ対応遺伝子

マウス[2]  NM_001112698, NM_013609
ラット[2]  NM_001112698, NM_013609

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1383421
1692298
2025430
2374737
2906326
3871525
6327169
6330750
6648531
6688123
7789166
7806500
8178451
8615794
8808283
8895847
9069267
9182757
9252186
9351801
9575168
9915784
10022904
10322959
10391209
10490030
10629055
10681572
10708862
10712923
10764727
10806167
11157096
11244088
11278287
11487608
11520933
11729324
11738045
11830582
11877300
11935372
12205295
12371150
12376548
12397373
12453472
12477932
12531456
12676754
12676795
12787561
12787574
12900521
12918708
12925217
14587217
14708938
14960584
14970904
14976160
14985763
15128850
15131306
15258592
15361847
15489334
15523689
15544837
15681836
15710408
15721744
15829579
16079148
16153003
16215275
16284401
16313302
16319926
16546643
16630834
16710414
16741963
16786155
16832412
16839849
16919030
16939974
16997282
17081983
17192954
17335080
17487982
17638883
17673289
17703412
17724343
17850422
17854142
17881264
17893397
17905097
17992191
18068123
18179783
18191449
18199526
18203754
18221326
18280641
18300262
18305571
18349121
18420729
18438945
18596692
18635195
18727839
18763222
18780967
18810245
18830907
18922682
18922683
19023688
19038326
19038341
19054925
19063739
19076929
19086053
19120874
19169037
19177265
19183217
19221293
19258923
19264868
19399531
19403065
19475530
19490633
19560628
19598235
19626992
19639490
19649262
19651702
19668232
19695094
19758188
19844736
19874574
19934806
19945432
19950533
19957796
19958603
20119692
20219210
20233324
20360245
20375017
20398908
20503287
20518854
20542022
20680101
20854189
20863878
20881126
20889312
20923384
20978020
21047631
21085492
21153361
21217078
21294249
21321391
21358750
21378097
21387003
21397006
21429417
21596795
21621608
21673280
21693611
21768088
21826717
21893340
22036954
22040304
22105621
22192858
22251933
22272270
22301435
22330829
22411587
22454143
22517242
22537619
22625872
22703891
22731611
22789557
22804708
22932111
22948388
22948508
22954667
23028581
23034254
23086522
23091165
23095849
23128606
23234779
23398122
23535911
23542336
23561736
23574818
23608378
23637956
23769609
23778138
23869086
23883529
23912036
23959444
23973519
23989259
24180625
24212932
24585880

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0007202  activation of phospholipase C activity
GO:0008344  adult locomotory behavior
GO:0008625  induction of apoptosis via death domain receptors
GO:0006954  inflammatory response
GO:0007613  memory
GO:0043066  negative regulation of apoptosis
GO:0045786  negative regulation of cell cycle
GO:0043524  negative regulation of neuron apoptosis
GO:0032455  nerve growth factor processing
GO:0048011  nerve growth factor receptor signaling pathway
GO:0031175  neuron projection development
GO:0007422  peripheral nervous system development
GO:0048015  phosphoinositide-mediated signaling
GO:0043065  positive regulation of apoptosis
GO:0045773  positive regulation of axon extension
GO:0050772  positive regulation of axonogenesis
GO:0010628  positive regulation of gene expression
GO:0051388  positive regulation of nerve growth factor receptor signaling pathway
GO:0045666  positive regulation of neuron differentiation
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0051091  positive regulation of transcription factor activity
GO:0007265  Ras protein signal transduction
GO:0050770  regulation of axonogenesis
GO:0043281  regulation of caspase activity
GO:0046928  regulation of neurotransmitter secretion
GO:0042493  response to drug
GO:0051602  response to electrical stimulus
GO:0051384  response to glucocorticoid stimulus
GO:0032496  response to lipopolysaccharide
GO:0009612  response to mechanical stimulus
GO:0035094  response to nicotine
GO:0010193  response to ozone
GO:0043434  response to peptide hormone stimulus
GO:0009314  response to radiation
GO:0019233  sensory perception of pain
GO:0007264  small GTPase mediated signal transduction
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005768  endosome
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen

Molecular Function

GO:0008083  growth factor activity
GO:0005163  nerve growth factor receptor binding
GO:0005057  receptor signaling protein activity