NK3 homeobox 1

詳細情報を見る

同義遺伝子名

Homeobox protein Nkx-3.1, family 3, NKX3A, NKX3.1, NKX3-1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:12.90

骨髄:19.70

脂肪:-

骨:-

皮膚:9.60

GeneChip

大脳:4.59

小脳:4.47

脳幹:4.67

脳梁:4.53

松果体:-

末梢神経:4.90

脊柱:4.89

網膜:-

目:-

動脈:4.74

静脈:4.63

リンパ節:4.80

末梢血:-

脾臓:5.39

胸腺:4.33

骨髄:4.65

脂肪:4.83

骨:-

皮膚:4.62

CAGE

大脳:0.62

小脳:-

脳幹:0.91

脳梁:0.63

松果体:0.77

末梢神経:-

脊柱:1.02

網膜:-

目:-

動脈:2.61

静脈:0.70

リンパ節:2.32

末梢血:-

脾臓:0.80

胸腺:0.23

骨髄:-

脂肪:0.71

骨:-

皮膚:-

RNA-seq

大脳:0.18

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.03

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.18

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:9.10

胎盤:-

前立腺:326.70

卵巣:37.30

精巣:43.30

心臓:-

骨格筋:20.10

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:14.70

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.65

胎盤:4.08

前立腺:11.44

卵巣:4.86

精巣:8.40

心臓:4.97

骨格筋:5.20

食道:5.57

胃:4.73

腸:4.88

結腸:4.74

肝臓:4.69

肺:4.98

膀胱:-

腎臓:4.58

下垂体:4.71

甲状腺:4.79

副腎:5.65

膵臓:4.38

乳腺:5.05

唾液腺:6.98

CAGE

子宮:0.99

胎盤:0.30

前立腺:4.83

卵巣:1.44

精巣:3.40

心臓:1.26

骨格筋:1.18

食道:0.97

胃:-

腸:0.43

結腸:0.84

肝臓:1.41

肺:1.27

膀胱:0.98

腎臓:0.58

下垂体:0.50

甲状腺:0.85

副腎:-

膵臓:0.58

乳腺:1.36

唾液腺:3.19

RNA-seq

子宮:-

胎盤:-

前立腺:2.35

卵巣:0.41

精巣:1.95

心臓:0.26

骨格筋:1.09

食道:-

胃:-

腸:-

結腸:0.50

肝臓:0.46

肺:0.67

膀胱:-

腎臓:0.13

下垂体:-

甲状腺:0.26

副腎:0.15

膵臓:-

乳腺:0.46

唾液腺:-

IDs

Refseq ID	NM_006167
Gene ID	4824
Unigene ID	Hs.55999
Probe set ID	209706_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000167034
GTEx ID	ENSG00000167034

オーソログ対応遺伝子

マウス[1]	NM_010921
ラット[1]	NM_001034144

染色体

8p21.2 [23,536,206 - 23,540,440]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0030521	androgen receptor signaling pathway
GO:0060442	branching involved in prostate gland morphogenesis
GO:0048754	branching morphogenesis of a tube
GO:0071456	cellular response to hypoxia
GO:0071347	cellular response to interleukin-1
GO:0071383	cellular response to steroid hormone stimulus
GO:0071356	cellular response to tumor necrosis factor
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0007507	heart development
GO:0008584	male gonad development
GO:0001656	metanephros development
GO:0007275	multicellular organismal development
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0010629	negative regulation of gene expression
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
GO:0045930	negative regulation of mitotic cell cycle
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0060037	pharyngeal system development
GO:0043280	positive regulation of caspase activity
GO:0010942	positive regulation of cell death
GO:0051781	positive regulation of cell division
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0045931	positive regulation of mitotic cell cycle
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045860	positive regulation of protein kinase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0043491	protein kinase B signaling cascade
GO:0006355	regulation of transcription, DNA-dependent
GO:0033574	response to testosterone stimulus
GO:0007431	salivary gland development
GO:0001756	somitogenesis

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Molecular Function

GO:0004882	androgen receptor activity
GO:0008656	caspase activator activity
GO:0044212	DNA regulatory region binding
GO:0030284	estrogen receptor activity
GO:0030331	estrogen receptor binding
GO:0042826	histone deacetylase binding
GO:0005515	protein binding
GO:0030295	protein kinase activator activity
GO:0043621	protein self-association
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

NK3 homeobox 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function