nitric oxide synthase 2, inducible

詳細情報を見る

同義遺伝子名

Nitric oxide synthase, inducible, iNOS, Inducible NOS, Inducible NO synthase, INOS, Hepatocyte NOS, nitric oxide synthase 2A (inducible, hepatocytes), NOS2A, NOS, HEP-NOS, NOS2, NOS type II

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.70 小脳:4.91 脳幹:4.72 脳梁:4.52 松果体:- 末梢神経:4.46 脊柱:4.43 網膜:- 目:- 動脈:4.66 静脈:4.61 リンパ節:4.53 末梢血:- 脾臓:4.36 胸腺:4.46 骨髄:4.74 脂肪:4.58 骨:- 皮膚:4.71
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:1.10 静脈:0 リンパ節:0.17 末梢血:- 脾臓:0 胸腺:0.12 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.71 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.45 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.14 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.54 胎盤:4.49 前立腺:4.41 卵巣:4.64 精巣:4.69 心臓:4.50 骨格筋:4.72 食道:4.55 胃:4.41 腸:4.82 結腸:5.16 肝臓:4.56 肺:4.56 膀胱:- 腎臓:4.62 下垂体:4.62 甲状腺:4.43 副腎:4.63 膵臓:5.02 乳腺:4.37 唾液腺:4.67
CAGE 子宮:0.09 胎盤:0 前立腺:0 卵巣:0 精巣:0.10 心臓:0 骨格筋:0 食道:0 胃:- 腸:1.52 結腸:0.73     肝臓:0    肺:0.10 膀胱:0 腎臓:0 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.13 卵巣:0.26 精巣:0.27 心臓:0.07 骨格筋:0.11 食道:- 胃:- 腸:- 結腸:0.12     肝臓:0        肺:1.91    膀胱:- 腎臓:0.34 下垂体:- 甲状腺:0.07 副腎:1.93 膵臓:- 乳腺:0.19 唾液腺:-

IDs

Refseq ID NM_000625
Gene ID 4843
Unigene ID -
Probe set ID 210037_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000007171
GTEx ID ENSG00000007171

オーソログ対応遺伝子

マウス[1]  NM_010927
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006527  arginine catabolic process
GO:0007596  blood coagulation
GO:0071346  cellular response to interferon-gamma
GO:0071222  cellular response to lipopolysaccharide
GO:0042742  defense response to bacterium
GO:0050829  defense response to Gram-negative bacterium
GO:0006954  inflammatory response
GO:0002227  innate immune response in mucosa
GO:0051701  interaction with host
GO:0045776  negative regulation of blood pressure
GO:0010629  negative regulation of gene expression
GO:0042177  negative regulation of protein catabolic process
GO:0006809  nitric oxide biosynthetic process
GO:0007263  nitric oxide mediated signal transduction
GO:0018119  peptidyl-cysteine S-nitrosylation
GO:0031284  positive regulation of guanylate cyclase activity
GO:0051712  positive regulation of killing of cells of another organism
GO:0001912  positive regulation of leukocyte mediated cytotoxicity
GO:0045909  positive regulation of vasodilation
GO:0042127  regulation of cell proliferation
GO:0043457  regulation of cellular respiration
GO:0050796  regulation of insulin secretion
GO:0009617  response to bacterium
GO:0001666  response to hypoxia
GO:0006801  superoxide metabolic process

Cellular Component

GO:0030863  cortical cytoskeleton
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005622  intracellular
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005777  peroxisome

Molecular Function

GO:0034618  arginine binding
GO:0005516  calmodulin binding
GO:0050660  FAD binding
GO:0010181  FMN binding
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0050661  NADP or NADPH binding
GO:0003958  NADPH-hemoprotein reductase activity
GO:0004517  nitric-oxide synthase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0005102  receptor binding
GO:0034617  tetrahydrobiopterin binding