Notch homolog 1, translocation-associated (Drosophila)

詳細情報を見る

同義遺伝子名

Notch 1, Neurogenic locus notch homolog protein 1 precursor, hN1, Translocation-associated notch protein TAN-1, TAN1, NOTCH1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:30.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:237.30 目:41.10 動脈:- 静脈:133.30 リンパ節:192.10 末梢血:18.20 脾臓:- 胸腺:12.90 骨髄:137.80 脂肪:161.30 骨:- 皮膚:33.60
GeneChip 大脳:6.45 小脳:5.61 脳幹:6.45 脳梁:7.05 松果体:- 末梢神経:6.40 脊柱:6.55 網膜:- 目:- 動脈:6.24 静脈:6.15 リンパ節:6.78 末梢血:- 脾臓:7.37 胸腺:6.91 骨髄:6.05 脂肪:6.61 骨:- 皮膚:6.83
CAGE 大脳:2.58 小脳:- 脳幹:2.80 脳梁:3.54 松果体:1.77 末梢神経:- 脊柱:2.53 網膜:- 目:- 動脈:2.84 静脈:3.43 リンパ節:3.23 末梢血:- 脾臓:3.36 胸腺:4.13 骨髄:- 脂肪:3.49 骨:- 皮膚:-
RNA-seq 大脳:1.56 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.28 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.13 骨:- 皮膚:-
EST 子宮:45.60 胎盤:14.60 前立腺:33.80 卵巣:37.30 精巣:13 心臓:114.90 骨格筋:- 食道:- 胃:- 腸:- 結腸:76.30     肝臓:-        肺:34.20    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:18.60 唾液腺:-
GeneChip 子宮:6.54 胎盤:6.13 前立腺:6.30 卵巣:6.13 精巣:5.17 心臓:6.19 骨格筋:5.65 食道:6.70 胃:6.31 腸:6.45 結腸:7.06 肝臓:6.41 肺:7.16 膀胱:- 腎臓:6.54 下垂体:5.55 甲状腺:5.98 副腎:6.08 膵臓:5.99 乳腺:6.94 唾液腺:6.59
CAGE 子宮:3.33 胎盤:2.57 前立腺:3.16 卵巣:3.04 精巣:2.40 心臓:2.98 骨格筋:2.41 食道:3.23 胃:- 腸:2.53 結腸:3.42     肝臓:2.65    肺:3.77 膀胱:3.19 腎臓:2.49 下垂体:1.69 甲状腺:2.60 副腎:- 膵臓:2.60 乳腺:3.33 唾液腺:2.66
RNA-seq 子宮:- 胎盤:- 前立腺:2.50 卵巣:2.39 精巣:1.58 心臓:1.37 骨格筋:0.86 食道:- 胃:- 腸:- 結腸:2.61     肝臓:1.28        肺:3.11    膀胱:- 腎臓:1.92 下垂体:- 甲状腺:1.52 副腎:3.12 膵臓:- 乳腺:3.01 唾液腺:-

IDs

Refseq ID NM_017617
Gene ID 4851
Unigene ID Hs.495473
Probe set ID 218902_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000148400
GTEx ID ENSG00000148400

オーソログ対応遺伝子

マウス[4]  NM_008714
ラット[2]  NM_001105721

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0042640  anagen
GO:0003180  aortic valve morphogenesis
GO:0060842  arterial endothelial cell differentiation
GO:0003162  atrioventricular node development
GO:0003181  atrioventricular valve morphogenesis
GO:0009912  auditory receptor cell fate commitment
GO:0007409  axonogenesis
GO:0048754  branching morphogenesis of a tube
GO:0003209  cardiac atrium morphogenesis
GO:0003207  cardiac chamber formation
GO:0060317  cardiac epithelial to mesenchymal transition
GO:0003214  cardiac left ventricle morphogenesis
GO:0060038  cardiac muscle cell proliferation
GO:0055008  cardiac muscle tissue morphogenesis
GO:0003213  cardiac right atrium morphogenesis
GO:0003219  cardiac right ventricle formation
GO:0060411  cardiac septum morphogenesis
GO:0060948  cardiac vascular smooth muscle cell development
GO:0003208  cardiac ventricle morphogenesis
GO:0001708  cell fate specification
GO:0003273  cell migration involved in endocardial cushion formation
GO:0071372  cellular response to follicle-stimulating hormone stimulus
GO:0007386  compartment specification
GO:0060982  coronary artery morphogenesis
GO:0003169  coronary vein morphogenesis
GO:0007368  determination of left/right symmetry
GO:0035116  embryonic hindlimb morphogenesis
GO:0060956  endocardial cell differentiation
GO:0003203  endocardial cushion morphogenesis
GO:0003157  endocardium development
GO:0003160  endocardium morphogenesis
GO:0007492  endoderm development
GO:0001837  epithelial to mesenchymal transition
GO:0003198  epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0030900  forebrain development
GO:0007440  foregut morphogenesis
GO:0010467  gene expression
GO:0010001  glial cell differentiation
GO:0003241  growth involved in heart morphogenesis
GO:0031069  hair follicle morphogenesis
GO:0007507  heart development
GO:0001947  heart looping
GO:0006959  humoral immune response
GO:0006955  immune response
GO:0001701  in utero embryonic development
GO:0002437  inflammatory response to antigenic stimulus
GO:0030216  keratinocyte differentiation
GO:0070986  left/right axis specification
GO:0001889  liver development
GO:0030324  lung development
GO:0014031  mesenchymal cell development
GO:0003192  mitral valve formation
GO:0030514  negative regulation of BMP signaling pathway
GO:0045955  negative regulation of calcium ion-dependent exocytosis
GO:0043086  negative regulation of catalytic activity
GO:0090051  negative regulation of cell migration involved in sprouting angiogenesis
GO:0008285  negative regulation of cell proliferation
GO:0010812  negative regulation of cell-substrate adhesion
GO:0060253  negative regulation of glial cell proliferation
GO:0045662  negative regulation of myoblast differentiation
GO:0010832  negative regulation of myotube differentiation
GO:0050768  negative regulation of neurogenesis
GO:0048715  negative regulation of oligodendrocyte differentiation
GO:0030279  negative regulation of ossification
GO:0045668  negative regulation of osteoblast differentiation
GO:0046533  negative regulation of photoreceptor cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0021915  neural tube development
GO:0007220  Notch receptor processing
GO:0007219  Notch signaling pathway
GO:0003344  pericardium morphogenesis
GO:0043065  positive regulation of apoptosis
GO:0048711  positive regulation of astrocyte differentiation
GO:0030513  positive regulation of BMP signaling pathway
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0046427  positive regulation of JAK-STAT cascade
GO:0045618  positive regulation of keratinocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0007221  positive regulation of transcription of Notch receptor target
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060740  prostate gland epithelium morphogenesis
GO:0003184  pulmonary valve morphogenesis
GO:0060768  regulation of epithelial cell proliferation involved in prostate gland development
GO:0003270  regulation of second heart field cardioblast proliferation by Notch signaling pathway
GO:0014807  regulation of somitogenesis
GO:0003256  regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006355  regulation of transcription, DNA-dependent
GO:0032495  response to muramyl dipeptide
GO:0060528  secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0048103  somatic stem cell division
GO:0002040  sprouting angiogenesis
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0035148  tube lumen formation
GO:0060979  vasculogenesis involved in coronary vascular morphogenesis
GO:0060843  venous endothelial cell differentiation
GO:0060412  ventricular septum morphogenesis
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0009986  cell surface
GO:0005829  cytosol
GO:0005789  endoplasmic reticulum membrane
GO:0005576  extracellular region
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0031490  chromatin DNA binding
GO:0019899  enzyme binding
GO:0004857  enzyme inhibitor activity
GO:0005515  protein binding
GO:0004872  receptor activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity