forkhead box P3

詳細情報を見る

同義遺伝子名

AIID, enteropathy, MGC141961, JM2, DIETER, XPID, SCURFIN, Scurfin, PIDX, MGC141963, forkhead box P3, polyendocrinopathy, FOXP3, IPEX, Forkhead box protein P3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.46 小脳:5.69 脳幹:5.48 脳梁:5.34 松果体:- 末梢神経:5.19 脊柱:5.25 網膜:- 目:- 動脈:5.56 静脈:5.63 リンパ節:5.37 末梢血:- 脾臓:5.18 胸腺:5.12 骨髄:5.40 脂肪:5.41 骨:- 皮膚:5.62
CAGE 大脳:0.00 小脳:- 脳幹:0 脳梁:0.07 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.34 静脈:2.40 リンパ節:2.64 末梢血:- 脾臓:1.29 胸腺:2.59 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.23 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.34 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.12 骨:- 皮膚:-
EST nodata
GeneChip 子宮:5.30 胎盤:5.22 前立腺:5.13 卵巣:5.31 精巣:5.13 心臓:5.60 骨格筋:5.66 食道:5.40 胃:5.40 腸:5.60 結腸:5.36 肝臓:5.41 肺:5.48 膀胱:- 腎臓:5.46 下垂体:5.37 甲状腺:5.09 副腎:5.65 膵臓:6.07 乳腺:5.15 唾液腺:5.67
CAGE 子宮:0.30 胎盤:0.08 前立腺:0.21 卵巣:0.14 精巣:0.10 心臓:0.03 骨格筋:0 食道:0.46 胃:- 腸:0.33 結腸:0.12     肝臓:0    肺:0.74 膀胱:0.58 腎臓:0.08 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0.36
RNA-seq 子宮:- 胎盤:- 前立腺:0.07 卵巣:0.07 精巣:0.90 心臓:0.04 骨格筋:0.15 食道:- 胃:- 腸:- 結腸:0.02     肝臓:0.19        肺:0.31    膀胱:- 腎臓:0.07 下垂体:- 甲状腺:0.36 副腎:1.39 膵臓:- 乳腺:0.22 唾液腺:-

IDs

Refseq ID NM_001114377
Gene ID 50943
Unigene ID -
Probe set ID 221334_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000049768
GTEx ID ENSG00000049768

オーソログ対応遺伝子

マウス[1]  NM_001199347, NM_001199348, NM_054039
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001782  B cell homeostasis
GO:0043010  camera-type eye development
GO:0021757  caudate nucleus development
GO:0002361  CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0021549  cerebellum development
GO:0021987  cerebral cortex development
GO:0006338  chromatin remodeling
GO:0001816  cytokine production
GO:0009790  embryonic development
GO:0040007  growth
GO:0048286  lung alveolus development
GO:0002262  myeloid cell homeostasis
GO:0046007  negative regulation of activated T cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0002677  negative regulation of chronic inflammatory response
GO:0032792  negative regulation of CREB transcription factor activity
GO:0042036  negative regulation of cytokine biosynthetic process
GO:0050710  negative regulation of cytokine secretion
GO:0035067  negative regulation of histone acetylation
GO:0031064  negative regulation of histone deacetylation
GO:0050777  negative regulation of immune response
GO:0045077  negative regulation of interferon-gamma biosynthetic process
GO:0032689  negative regulation of interferon-gamma production
GO:0032693  negative regulation of interleukin-10 production
GO:0045085  negative regulation of interleukin-2 biosynthetic process
GO:0032703  negative regulation of interleukin-2 production
GO:0032713  negative regulation of interleukin-4 production
GO:0032714  negative regulation of interleukin-5 production
GO:0032715  negative regulation of interleukin-6 production
GO:0048294  negative regulation of isotype switching to IgE isotypes
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0002725  negative regulation of T cell cytokine production
GO:0042130  negative regulation of T cell proliferation
GO:0043433  negative regulation of transcription factor activity
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032720  negative regulation of tumor necrosis factor production
GO:0007389  pattern specification process
GO:0032831  positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0060501  positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0035066  positive regulation of histone acetylation
GO:0033092  positive regulation of immature T cell proliferation in the thymus
GO:0032753  positive regulation of interleukin-4 production
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0002851  positive regulation of peripheral T cell tolerance induction
GO:0002669  positive regulation of T cell anergy
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032914  positive regulation of transforming growth factor-beta1 production
GO:0009791  post-embryonic development
GO:0021758  putamen development
GO:0048302  regulation of isotype switching to IgG isotypes
GO:0006355  regulation of transcription, DNA-dependent
GO:0009615  response to virus
GO:0060013  righting reflex
GO:0007519  skeletal muscle tissue development
GO:0048745  smooth muscle tissue development
GO:0042110  T cell activation
GO:0043029  T cell homeostasis
GO:0002456  T cell mediated immunity
GO:0050852  T cell receptor signaling pathway
GO:0002513  tolerance induction to self antigen
GO:0042297  vocal learning

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0035035  histone acetyltransferase binding
GO:0042826  histone deacetylase binding
GO:0046872  metal ion binding
GO:0051059  NF-kappaB binding
GO:0051525  NFAT protein binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity