lymphoid enhancer-binding factor 1

同義遺伝子名

LEF1, LEF-1, lymphoid enhancer-binding factor 1, TCF1ALPHA, TCF1-alpha, T cell-specific transcription factor 1-alpha, Lymphoid enhancer-binding factor 1, DKFZp586H0919

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:6.44

小脳:5.45

脳幹:6.36

脳梁:6.07

松果体:-

末梢神経:7.28

脊柱:6.36

網膜:-

目:-

動脈:5.11

静脈:5.31

リンパ節:9.06

末梢血:-

脾臓:7.88

胸腺:12.16

骨髄:7.26

脂肪:5.83

骨:-

皮膚:6.20

CAGE

大脳:1.85

小脳:-

脳幹:2.14

脳梁:2.35

松果体:2.00

末梢神経:-

脊柱:1.88

網膜:-

目:-

動脈:1.57

静脈:4.83

リンパ節:4.18

末梢血:-

脾臓:2.83

胸腺:6.71

骨髄:-

脂肪:1.21

骨:-

皮膚:-

RNA-seq

大脳:0.13

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.32

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.00

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:7.38

胎盤:5.91

前立腺:6.42

卵巣:6.37

精巣:8.02

心臓:4.90

骨格筋:4.88

食道:5.56

胃:5.60

腸:5.59

結腸:5.74

肝臓:5.12

肺:6.07

膀胱:-

腎臓:5.76

下垂体:5.32

甲状腺:6.31

副腎:8.46

膵臓:4.39

乳腺:6.52

唾液腺:4.82

CAGE

子宮:2.52

胎盤:1.86

前立腺:1.91

卵巣:1.87

精巣:2.95

心臓:0.70

骨格筋:0.49

食道:2.01

胃:-

腸:1.52

結腸:1.21

肝臓:0

肺:2.19

膀胱:1.76

腎臓:1.86

下垂体:1.11

甲状腺:2.16

副腎:-

膵臓:1.21

乳腺:2.02

唾液腺:1.58

RNA-seq

子宮:-

胎盤:-

前立腺:0.00

卵巣:0.28

精巣:1.25

心臓:0.03

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.68

肝臓:0.00

肺:0.51

膀胱:-

腎臓:0.45

下垂体:-

甲状腺:0.34

副腎:0.07

膵臓:-

乳腺:0.06

唾液腺:-

IDs

Refseq ID	NM_001130714
Gene ID	51176
Unigene ID	-
Probe set ID	221558_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000138795
GTEx ID	ENSG00000138795

オーソログ対応遺伝子

マウス[1]	NM_010703
ラット [0]

染色体

4q25 [108,968,701 - 109,090,112]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000910	High mobility group, HMG1/HMG2
IPR009071	High mobility group, superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0046632	alpha-beta T cell differentiation
GO:0060033	anatomical structure regression
GO:0060561	apoptosis involved in morphogenesis
GO:0042100	B cell proliferation
GO:0030509	BMP signaling pathway
GO:0007420	brain development
GO:0060326	cell chemotaxis
GO:0071345	cellular response to cytokine stimulus
GO:0071353	cellular response to interleukin-4
GO:0060710	chorio-allantoic fusion
GO:0021542	dentate gyrus development
GO:0030326	embryonic limb morphogenesis
GO:0001837	epithelial to mesenchymal transition
GO:0048069	eye pigmentation
GO:0060325	face morphogenesis
GO:0021873	forebrain neuroblast division
GO:0021879	forebrain neuron differentiation
GO:0021943	formation of radial glial scaffolds
GO:0048699	generation of neurons
GO:0043966	histone H3 acetylation
GO:0043967	histone H4 acetylation
GO:0021854	hypothalamus development
GO:0006917	induction of apoptosis
GO:0030879	mammary gland development
GO:0048747	muscle fiber development
GO:0043066	negative regulation of apoptosis
GO:0043154	negative regulation of caspase activity
GO:0022408	negative regulation of cell-cell adhesion
GO:0043392	negative regulation of DNA binding
GO:0032696	negative regulation of interleukin-13 production
GO:0032713	negative regulation of interleukin-4 production
GO:0032714	negative regulation of interleukin-5 production
GO:0045843	negative regulation of striated muscle tissue development
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001755	neural crest cell migration
GO:0022008	neurogenesis
GO:0030223	neutrophil differentiation
GO:0042475	odontogenesis of dentine-containing tooth
GO:0001649	osteoblast differentiation
GO:0060021	palate development
GO:0048341	paraxial mesoderm formation
GO:0001569	patterning of blood vessels
GO:0043923	positive regulation by host of viral transcription
GO:0090068	positive regulation of cell cycle process
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0022409	positive regulation of cell-cell adhesion
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010628	positive regulation of gene expression
GO:0030854	positive regulation of granulocyte differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0021861	radial glial cell differentiation in the forebrain
GO:0022407	regulation of cell-cell adhesion
GO:0016202	regulation of striated muscle tissue development
GO:0050909	sensory perception of taste
GO:0001756	somitogenesis
GO:0002040	sprouting angiogenesis
GO:0033153	T cell receptor V(D)J recombination
GO:0045063	T-helper 1 cell differentiation
GO:0043586	tongue development
GO:0006366	transcription from RNA polymerase II promoter
GO:0016055	Wnt receptor signaling pathway
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0032993	protein-DNA complex
GO:0005667	transcription factor complex

Molecular Function

GO:0070016	armadillo repeat domain binding
GO:0008013	beta-catenin binding
GO:0070742	C2H2 zinc finger domain binding
GO:0043027	caspase inhibitor activity
GO:0003682	chromatin binding
GO:0008301	DNA bending activity
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0030284	estrogen receptor activity
GO:0030331	estrogen receptor binding
GO:0045295	gamma-catenin binding
GO:0042393	histone binding
GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

lymphoid enhancer-binding factor 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function