platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

同義遺伝子名

PDGFB, FLJ12858, PDGF2, SIS, c-sis, PDGF-2, Platelet-derived growth factor beta polypeptide, SSV, PDGF B-chain, Becaplermin, Platelet-derived growth factor B chain precursor

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:5.90

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:18.90

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:6.80

小脳:6.97

脳幹:6.81

脳梁:6.78

松果体:-

末梢神経:6.73

脊柱:6.72

網膜:-

目:-

動脈:6.81

静脈:6.88

リンパ節:6.79

末梢血:-

脾臓:6.61

胸腺:6.02

骨髄:6.64

脂肪:7.14

骨:-

皮膚:6.78

CAGE

大脳:2.35

小脳:-

脳幹:2.72

脳梁:3.04

松果体:2.23

末梢神経:-

脊柱:2.81

網膜:-

目:-

動脈:2.68

静脈:2.74

リンパ節:1.69

末梢血:-

脾臓:1.62

胸腺:0.94

骨髄:-

脂肪:3.31

骨:-

皮膚:-

RNA-seq

大脳:0.39

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.29

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.32

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:8.50

肝臓:-

肺:-

膀胱:-

腎臓:41.60

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:6.58

胎盤:7.09

前立腺:6.32

卵巣:6.63

精巣:6.39

心臓:7.16

骨格筋:7.01

食道:6.79

胃:6.73

腸:6.80

結腸:6.90

肝臓:6.63

肺:7

膀胱:-

腎臓:6.98

下垂体:6.71

甲状腺:6.84

副腎:6.98

膵臓:7.17

乳腺:6.76

唾液腺:6.70

CAGE

子宮:2.78

胎盤:3.82

前立腺:2.11

卵巣:2.04

精巣:2.33

心臓:3.25

骨格筋:2.70

食道:2.46

胃:-

腸:1.74

結腸:2.60

肝臓:1.07

肺:3.42

膀胱:2.51

腎臓:2.59

下垂体:1.60

甲状腺:2.37

副腎:-

膵臓:1.87

乳腺:3.66

唾液腺:1.67

RNA-seq

子宮:-

胎盤:-

前立腺:1.13

卵巣:0.36

精巣:0.67

心臓:1.39

骨格筋:0.84

食道:-

胃:-

腸:-

結腸:0.73

肝臓:0.08

肺:3.49

膀胱:-

腎臓:1.41

下垂体:-

甲状腺:0.49

副腎:0.87

膵臓:-

乳腺:1.13

唾液腺:-

IDs

Refseq ID	NM_002608
Gene ID	5155
Unigene ID	Hs.197613
Probe set ID	216061_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000100311
GTEx ID	ENSG00000100311

オーソログ対応遺伝子

マウス[2]	NM_011057
ラット[2]	NM_031524

染色体

22q13.1 [39,619,364 - 39,640,756]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0007596	blood coagulation
GO:0048514	blood vessel morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0060326	cell chemotaxis
GO:0016049	cell growth
GO:0030031	cell projection assembly
GO:0071363	cellular response to growth factor stimulus
GO:0071506	cellular response to mycophenolic acid
GO:0006260	DNA replication
GO:0001892	embryonic placenta development
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0030198	extracellular matrix organization
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0007507	heart development
GO:0030097	hemopoiesis
GO:0045087	innate immune response
GO:0002548	monocyte chemotaxis
GO:0030336	negative regulation of cell migration
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
GO:0010544	negative regulation of platelet activation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048011	nerve growth factor receptor signaling pathway
GO:0018105	peptidyl-serine phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0050918	positive chemotaxis
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0051781	positive regulation of cell division
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0050921	positive regulation of chemotaxis
GO:0045737	positive regulation of cyclin-dependent protein kinase activity
GO:0045740	positive regulation of DNA replication
GO:0001938	positive regulation of endothelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048146	positive regulation of fibroblast proliferation
GO:0003104	positive regulation of glomerular filtration
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0045840	positive regulation of mitosis
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0031954	positive regulation of protein amino acid autophosphorylation
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0042493	response to drug
GO:0032355	response to estradiol stimulus
GO:0001666	response to hypoxia
GO:0032868	response to insulin stimulus
GO:0009611	response to wounding
GO:0006929	substrate-bound cell migration
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005788	endoplasmic reticulum lumen
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0000139	Golgi membrane
GO:0031093	platelet alpha granule lumen

Molecular Function

GO:0042056	chemoattractant activity
GO:0005518	collagen binding
GO:0008083	growth factor activity
GO:0048407	platelet-derived growth factor binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0016176	superoxide-generating NADPH oxidase activator activity

platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function